Patents by Inventor Finn Bauer
Finn Bauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230398222Abstract: The present invention relates to a method for producing an amorphous solid dispersion of at least one active pharmaceutical ingredient in a polymer matrix. The Invention further relates to a pharmaceutical composition using polymers as an excipient and particularly to an improved pharmaceutical composition comprising polyvinyl alcohol grades with different degrees of hydrolysis, which is suitable to stabilize active pharmaceutical ingredients.Type: ApplicationFiled: October 20, 2021Publication date: December 14, 2023Applicant: MERCK PATENT GMBHInventors: Thomas KIPPING, Finn BAUER, Nicole DI GALLO, Anja-Nadine KNUETTEL, Alessandro Giuseppe ELIA
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Publication number: 20230390204Abstract: The present invention relates to pharmaceutical compositions using polymers as an excipient. Particularly, the invention relates to a pharmaceutical composition comprising polyvinyl alcohol which is suitable to enhance solubility of poorly soluble active pharmaceutical ingredients in aqueous media. The present invention also relates to a method for enhancing solubility of poorly soluble active pharmaceutical ingredients.Type: ApplicationFiled: October 27, 2021Publication date: December 7, 2023Applicant: Merck Patent GmbHInventors: Thomas KIPPING, Finn BAUER, Nicole DI GALLO, Anja-Nadine KNUETTEL, Alessandro Giuseppe ELIA
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Patent number: 11510988Abstract: The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands and exposed on the surface of the carrier system for use in targeted delivery and/or antigen display systems. Optionally one or more further bioactive agents may be encapsulated or embedded within or attached to or adsorbed onto the carrier system. The present invention is further directed to methods of their preparation and their uses in medical applications, such as targeted delivery of bioactive agents to specific tissues or cells and antigen display systems for the study, diagnosis, and treatment of traits, diseases and conditions that respond to said bioactive agents.Type: GrantFiled: January 11, 2018Date of Patent: November 29, 2022Assignee: Merck Patent GmbHInventors: Michael Platscher, Raymond Behrendt, Viola Groehn, Simone Hoertner, Marco Passafaro, Finn Bauer
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Patent number: 11040012Abstract: The present invention relates to premixes for the production of active compound-containing tablets which comprise polyvinyl alcohols (PVAs). The invention also relates to active compound-containing tablets which comprise a corresponding premix.Type: GrantFiled: July 3, 2015Date of Patent: June 22, 2021Assignee: Merck Patent GmbHInventors: Roberto Ognibene, Finn Bauer, Thorsten Wedel, Guenter Moddelmog
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Patent number: 10874615Abstract: The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.Type: GrantFiled: August 25, 2016Date of Patent: December 29, 2020Assignee: Merck Patent GmbHInventors: Finn Bauer, Thorsten Wedel, Guenter Moddelmog, Gudrun Birk, Roberto Ognibene, Dieter Lubda
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Patent number: 10828258Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.Type: GrantFiled: July 11, 2018Date of Patent: November 10, 2020Assignee: Merck Patent GmbHInventors: Roberto Ognibene, Finn Bauer, Thorsten Wedel, Guenter Moddelmog
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Publication number: 20200246270Abstract: The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.Type: ApplicationFiled: April 21, 2020Publication date: August 6, 2020Applicant: Merck Patent GmbHInventors: Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG, Gudrun BIRK, Roberto OGNIBENE, Dieter LUBDA
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Publication number: 20200214984Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.Type: ApplicationFiled: March 17, 2020Publication date: July 9, 2020Applicant: Merck Patent GmbHInventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
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Publication number: 20190038562Abstract: The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the preparation of such formulations. The invention additionally relates to the use of these novel pharmaceutical administration forms as medicaments for the treatment of diseases which require delayed release of the active ingredient, such as hypertension, or asthmatic diseases.Type: ApplicationFiled: August 25, 2016Publication date: February 7, 2019Applicant: Merck Patent GmbHInventors: Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG, Gudrun BIRK, Roberto OGNIBENE, Dieter LUBDA
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Publication number: 20180318224Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.Type: ApplicationFiled: July 11, 2018Publication date: November 8, 2018Applicant: Merck Patent GmbHInventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
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Publication number: 20180250233Abstract: The present invention relates to formulations having extended release of active ingredient, comprising an active ingredient from BCS Class I having high solubility and high permeability in a polyvinyl alcohol-containing matrix, from which the active ingredient is released at a controlled rate over a therapeutically relevant time period independently of the composition of the release medium.Type: ApplicationFiled: August 25, 2016Publication date: September 6, 2018Applicant: MERCK PATENT GMBHInventors: Finn BAUER, Thorsten WEDEL, Gudrun BIRK, Roberto OGNIBENE, Dieter LUBDA, Guenter MODDELMOG
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Publication number: 20180207101Abstract: The present invention relates to premixes for the production of active compound-containing tablets which comprise polyvinyl alcohols (PVAs). The invention also relates to active compound-containing tablets which comprise a corresponding premix.Type: ApplicationFiled: July 3, 2015Publication date: July 26, 2018Applicant: Merck Patent GmbHInventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
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Publication number: 20180133334Abstract: The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands and exposed on the surface of the carrier system for use in targeted delivery and/or antigen display systems. Optionally one or more further bioactive agents may be encapsulated or embedded within or attached to or adsorbed onto the carrier system. The present invention is further directed to methods of their preparation and their uses in medical applications, such as targeted delivery of bioactive agents to specific tissues or cells and antigen display systems for the study, diagnosis, and treatment of traits, diseases and conditions that respond to said bioactive agents.Type: ApplicationFiled: January 11, 2018Publication date: May 17, 2018Applicant: Merck Patent GmbHInventors: Michael PLATSCHER, Raymond BEHRENDT, Viola GROEHN, Simone HOERTNER, Marco PASSAFARO, Finn BAUER
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Patent number: 9878044Abstract: The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands and exposed on the surface of the carrier system for use in targeted delivery and/or antigen display systems. Optionally one or more further bioactive agents may be encapsulated or embedded within or attached to or adsorbed onto the carrier system. The present invention is further directed to methods of their preparation and their uses in medical applications, such as targeted delivery of bioactive agents to specific tissues or cells and antigen display systems for the study, diagnosis, and treatment of traits, diseases and conditions that respond to said bioactive agents.Type: GrantFiled: March 11, 2013Date of Patent: January 30, 2018Assignee: MERCK PATENT GMBHInventors: Michael Wilhelm Platscher, Raymond Behrendt, Viola Groehn, Simone Rachel Hoertner, Marco Silvio Passafaro, Finn Bauer
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Patent number: 9796666Abstract: The present invention is directed to a new class of lipids, more specifically ether-lipids having a polar headgroup, as well as vesicles comprising these lipids, methods of their preparation as well as their uses in medical applications, wherein the ether-lipids are represented by general formula IType: GrantFiled: March 11, 2013Date of Patent: October 24, 2017Assignee: MERCK PATENT GmbHInventors: Michael Wilhelm Platscher, Raymond Behrendt, Viola Groehn, Simone Rachel Hoertner, Marco Silvio Passafaro, Finn Bauer
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Publication number: 20170216213Abstract: The present invention relates to directly compressible co-mixtures for the production of tablets having delayed release of active compound which comprise polyvinyl alcohols (PVAs) and microcrystalline celluloses (MCCs).Type: ApplicationFiled: July 3, 2015Publication date: August 3, 2017Applicant: Merck Patent GmbHInventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
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Publication number: 20170209380Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.Type: ApplicationFiled: July 3, 2015Publication date: July 27, 2017Applicant: Merck Patent GmbHInventors: Roberto OGNIBENE, Finn BAUER, Thorsten WEDEL, Guenter MODDELMOG
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Publication number: 20150030669Abstract: The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands and exposed on the surface of the carrier system for use in targeted delivery and/or antigen display systems. Optionally one or more further bioactive agents may be encapsulated or embedded within or attached to or adsorbed onto the carrier system. The present invention is further directed to methods of their preparation and their uses in medical applications, such as targeted delivery of bioactive agents to specific tissues or cells and antigen display systems for the study, diagnosis, and treatment of traits, diseases and conditions that respond to said bioactive agents.Type: ApplicationFiled: March 11, 2013Publication date: January 29, 2015Applicant: MERCK PATENT GMBHInventors: Michael Wilhelm Platscher, Raymond Behrendt, Viola Groehn, Simone Rachel Hoertner, Marco Silvio Passafaro, Finn Bauer
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Publication number: 20150030670Abstract: The present invention is directed to a new class of lipids, more specifically ether-lipids having a polar headgroup, as well as vesicles comprising these lipids, methods of their preparation as well as their uses in medical applications, wherein the ether-lipids are represented by general formula IType: ApplicationFiled: March 11, 2013Publication date: January 29, 2015Applicant: MERCK PATENT GmbHInventors: Michael Wilhelm Platscher, Raymond Behrendt, Viola Groehn, Simone Rachel Hoertner, Marco Silvio Passafaro, Finn Bauer