Patents by Inventor Fionula M. Brennan

Fionula M. Brennan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TNF.alpha. receptor-derived binding protein
    Patent number: 5633145
    Abstract: A polypeptide is provided which is capable of binding human TNF.alpha. and which has the first three cysteine-rich subdomains, but not the fourth cysteine-rich subdomain, of the extracellular binding domain of a receptor selected from the group consisting of the 55 kD and 75 kD receptors for human TNF.alpha.. The ability of the polypeptide to bind TNF.alpha. means that it can be used for treating diseases mediated by TNF.alpha. activity, such as rheumatoid arthritis.
    Type: Grant
    Filed: May 10, 1993
    Date of Patent: May 27, 1997
    Assignee: The Mathilda and Terence Kennedy Institute of Rheumatology
    Inventors: Marc Feldmann, Patrick W. Gray, Martin J. C. Turner, Fionula M. Brennan