Abstract: Described herein are methods and computer systems for classification of CD8 T-cell topology using a patient response-based linear cutoff model. A plurality of histology images of tissue samples in a plurality of patients are received by a computer system. An image analysis of the plurality of histology images is performed to obtain a CD8+ T-cell abundance in the tumor parenchyma and stroma in each of the plurality of histology images. Real inflammation scores and tumor infiltration scores are determined based on a polar coordinate transformation of the CD8+ T-cell abundance in the tumor parenchyma and stroma. Based on the real inflammation scores and tumor infiltration scores, a feature space is generated, and linear boundaries or linear cutoffs between a plurality of classifications in the feature space are identified based on the real inflammation scores, the tumor infiltration scores, and patient response data.

Abstract: RF transistor amplifier circuits are provided that comprise a circuit board and an RF transistor amplifier die. The RF transistor amplifier die is flip-chip mounted on an upper surface of the circuit board so that a gate terminal, a drain terminal and a source terminal of the die face the upper surface of the circuit board. These RF transistor amplifier circuits further include a heatsink mounted on an upper surface of the RF transistor amplifier die and a plurality of surface mount circuit elements mounted on the upper surface of the circuit board so that a footprint of the heatsink vertically overlaps each of the plurality of surface mount circuit elements.

Abstract: The present invention is to provide a method for personalizing a calendar by collecting web page information according to data entries in the calendar, which is applicable to a network system including a server and a terminal device connected to the server through the Internet and installed with calendar software. The method is designed that, after a user writes predetermined data entry into a calendar created by the calendar software and shown on the terminal device, the terminal device automatically collects web page information matching with the data entry from the Internet by way of the calendar software and the server. Once the web page information collected is properly sorted, the terminal device imbeds the web page information into the calendar or adds the web page information to the calendar as a plugin, thereby creating a personalized calendar which enables the user to obtain the desired information conveniently and rapidly.

Abstract: A computer-implemented system is provided, including a network consisting of the Internet, PSTN, and CATV network. The network is connected to multiple users' client systems, and also to multiple service provider systems. Each user has a user profile stored in a User Preference Database, while each service provider has service parameters defining the type of its service stored in a Service Database, both of which are connected to the network. The system further includes a Gatekeeper Server, which establishes voice communication among the client systems and the service provider systems. In operation, upon receiving a user's request for service, the Gatekeeper Server identifies one or more service providers whose service parameters match the user's request for service and the user's profile. Upon the user's selection of one such service provider, the Gatekeeper server automatically selects and establishes a preferred mode of voice connection between the user and the selected service provider.

Abstract: The present invention provides a method, system, and software for dynamically generating a customized menu page on a display of a client system coupled to a network, such as the Internet. The menu page includes a number of selectable icons, each associated with a particular Web site, service, Web guide channel, etc., that the user is likely to wish to access. The menu page is “customized” in the sense that each menu page is generated based on each user's network log history and preferences, as stored in a user preference database, so as to present only those information sources/services that he/she would want to access. The menu is “dynamically” generated in the sense that the user preference database is constantly updated so as to present a menu page that reflects the user's most recent preferences and history.