Patents by Inventor Flavio Moroni

Flavio Moroni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazolyl- and oxazolyl-isoquinolinones and methods for using them
    Patent number: 9265769
    Abstract: The present invention relates to substituted thiazolyl- and oxazolyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thiazolyl- and oxazolyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: February 23, 2016
    Inventors: Roberto Pellicciari, Flavio Moroni
  • Thienyl- and furanyl-isoquinolinones and methods for using them
    Patent number: 9079915
    Abstract: The present invention relates to substituted thienyl- and furanyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thienyl and furanyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: July 14, 2015
    Inventors: Roberto Pellicciari, Flavio Moroni, Eric Christian Hansen, Adam Matthew Gilbert, Peter John Larkin
  • Thiazolyl- And Oxazolyl-Isoquinolinones And Methods For Using Them
    Publication number: 20150133443
    Abstract: The present invention relates to substituted thiazolyl- and oxazolyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thiazolyl- and oxazolyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Application
    Filed: November 7, 2014
    Publication date: May 14, 2015
    Inventors: Roberto Pellicciari, Flavio Moroni
  • Thiazolyl- and oxazolyl-isoquinolinones and methods for using them
    Patent number: 8906935
    Abstract: The present invention relates to substituted thiazolyl- and oxazolyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thiazolyl- and oxazolyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: December 9, 2014
    Inventors: Roberto Pellicciari, Flavio Moroni, Adam Gilbert
  • Thienyl- and Furanyl-Isoquinolinones and Methods for Using Them
    Publication number: 20140107117
    Abstract: The present invention relates to substituted thienyl- and furanyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thienyl and furanyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 17, 2014
    Inventors: Roberto Pellicciari, Flavio Moroni
  • Thienyl-and furanyl-isoquinolinones and methods for using them
    Patent number: 8633215
    Abstract: The present invention relates to substituted thienyl- and furanyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thienyl and furanyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: January 21, 2014
    Inventors: Roberto Pellicciari, Flavio Moroni, Eric Christian Hansen, Adam Matthew Gilbert, Peter John Larkin
  • Thiazolyl- and Oxazolyl-Isoquinolinones and Methods for Using Them
    Publication number: 20130059843
    Abstract: The present invention relates to substituted thiazolyl- and oxazolyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thiazolyl- and oxazolyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Application
    Filed: October 18, 2012
    Publication date: March 7, 2013
    Inventors: Roberto Pellicciari, Flavio Moroni, Adam Gilbert
  • Thiazolyl-and oxazolyl-isoquinolinones and methods for using them
    Patent number: 8299090
    Abstract: The present invention relates to substituted thiazolyl- and oxazoyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thiazolyl- and oxazolyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: October 30, 2012
    Inventors: Roberto Pellicciari, Flavio Moroni, Adam Matthew Gilbert
  • THIENO[2,3-C] ISOQUINOLINES FOR USE AS INHIBITORS OF PARP
    Publication number: 20110237617
    Abstract: The present invention relates to compounds for the inhibition of poly(ADP-ribose) polymerase (PARP). In some embodiments, the compounds have the Formula: wherein the constituent variables are as defined herein. The invention further provides methods for the use of the compounds disclosed herein.
    Type: Application
    Filed: November 2, 2010
    Publication date: September 29, 2011
    Inventors: ROBERTO PELLICCIARI, FLAVIO MORONI
  • Thieno[2,3-c] isoquinolines for use as inhibitors of PARP
    Patent number: 7825129
    Abstract: The present invention relates to compounds for the inhibition of poly(ADP-ribose) polymerase (PARP). In some embodiments, the compounds have the Formula: wherein the constituent variables are as defined herein. The invention further provides methods for the use of the compounds disclosed herein.
    Type: Grant
    Filed: November 1, 2005
    Date of Patent: November 2, 2010
    Inventors: Roberto Pellicciari, Flavio Moroni
  • THIENYL-AND FURANYL-ISOQUINOLINONES AND METHODS FOR USING THEM
    Publication number: 20090325951
    Abstract: The present invention relates to substituted thienyl- and furanyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thienyl and furanyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Application
    Filed: June 18, 2009
    Publication date: December 31, 2009
    Inventors: Roberto Pellicciari, Flavio Moroni, Eric Christian Hansen, Adam Matthew Gilbert, Peter John Larkin
  • THIAZOLYL-AND OXAZOLYL-ISOQUINOLINONES AND METHODS FOR USING THEM
    Publication number: 20090318442
    Abstract: The present invention relates to substituted thiazolyl- and oxazoyl-isoquinolinones that act, for example, as modulators of poly(ADP-ribose) polymerase (PARP). The present invention also relates to processes for the preparation of substituted thiazolyl- and oxazolyl-isoquinolinones and to their use in treating various diseases and disorders.
    Type: Application
    Filed: June 18, 2009
    Publication date: December 24, 2009
    Applicant: Wyeth
    Inventors: Roberto PELLICCIARI, Flavio Moroni, Adam Matthew Gilbert
  • Thieno[2,3-c] isoquinolines for use as inhibitors of PARP
    Publication number: 20060094746
    Abstract: The present invention relates to compounds for the inhibition of poly(ADP-ribose) polymerase (PARP). In some embodiments, the compounds have the Formula: wherein the constituent variables are as defined herein. The invention further provides methods for the use of the compounds disclosed herein.
    Type: Application
    Filed: November 1, 2005
    Publication date: May 4, 2006
    Inventors: Roberto Pellicciari, Flavio Moroni
  • Thieno[2,3-c]iosquinolines for use as inhibitors of PARP
    Patent number: 6989388
    Abstract: The present invention relates to compounds for the inhibition of poly(ADP-ribose) polymerase (PARP). In some embodiments, the compounds have the Formula: wherein the constituent variables are as defined herein. The invention further provides methods for the use of the compounds disclosed herein.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: January 24, 2006
    Inventors: Roberto Pellicciari, Flavio Moroni
  • Thieno[2,3-c]iosquinolines for use as inhibitors of parp
    Publication number: 20040082789
    Abstract: Heterocyclic derivatives, including derivatives of thieno[2,3-c]isoquinolin-3-one and their use in therapy as inhibitors of poly(ADP-ribose) polymers (PARP), for use in the prevention and treatment of tissue damage due to ischaemia and reperfusion, degenerative diseases, inflammatory diseases, tumour diseases, leukaemia and/or sarcoma.
    Type: Application
    Filed: December 18, 2003
    Publication date: April 29, 2004
    Inventors: Roberto Pellicciari, Flavio Moroni
  • Kynurenic acid derivatives, their preparation and pharmaceutical compositions containing them
    Patent number: 5250541
    Abstract: Kynurenic acid derivatives useful as therapeutic agents in treating neurological disorders, for example, thiokynurenic acid, 7-chloro-thio-kynurenic acid, 7-trifluoromethyl-thiokynurenic acid, 7-methoxy-thiokynurenic acid and 5-fluoro-thiokynurenic acid.
    Type: Grant
    Filed: February 5, 1992
    Date of Patent: October 5, 1993
    Assignee: Fidia S.p.A.
    Inventors: Flavio Moroni, Roberto Pellicciari