Patents by Inventor Frédéric Pinston
Frédéric Pinston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230236542Abstract: A focus adjustment method for acquiring an image of a surface of interest of a sample by a holographic imager includes the steps of: placing the sample including at least one reference object having a known shape and described by characterising parameters having at least position parameters acquiring an image and determining the position of the reference object with respect to the acquisition plane, by applying a light diffraction model involving the spatial parameters of the reference object estimated by approximating the appearance of the reference object in the holographic image acquired, and determining the position of the surface of interest with respect to the acquisition plane from a position of the reference object and focus adjustment of the image acquisition.Type: ApplicationFiled: June 23, 2021Publication date: July 27, 2023Applicants: Biomerieux, Universite Jean Monnet Saint Etienne, Centre National de la Recherche Scientifique (CNRS)Inventors: Nicolas Faure, Frédéric Pinston, Corinne Fournier, Loïc Denis, Thomas Olivier
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Patent number: 10870876Abstract: A method for detecting a presence or an absence of at least one zone of inhibition, the method including a step consisting in depositing a volume of the sample in liquid form along a deposition zone extending along an axis at the surface of the agar culture medium and a step consisting in depositing a determined amount of a chemical agent at the surface of the agar culture medium, the deposit defining a potential zone of inhibition, the axis of the zone of deposition of the sample intersecting the potential zone of inhibition.Type: GrantFiled: July 6, 2016Date of Patent: December 22, 2020Assignee: BIOMERIEUXInventors: Laurent Drazek, Agnés Dupont-Fillard, Frédéric Pinston, Hervé Rostaing
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Patent number: 10865376Abstract: A method detects the presence or absence of at least one first inhibition zone having a culture of biological particles on a culture medium in the presence of a chemical agent. The method of detection has a first step of seeding the culture medium with the biological particles, a second step in which the culture medium receives the chemical agent, a third step of incubation of the culture medium, and a fourth step of measurement of the first inhibition zone of the culture medium, which includes a first phase of taking an image of the first inhibition zone by ombroscopy.Type: GrantFiled: June 29, 2015Date of Patent: December 15, 2020Assignee: BIOMERIEUXInventors: Laurent Drazek, Frédéric Pinston
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Patent number: 10746662Abstract: A method and system incorporating a process for analyzing a sample to be tested to determine the presence of or to quantify an analyte in the sample. The process employs a reaction which produces a reaction medium derived from the sample that possesses fluorescence properties, in response to illumination by a light source. The process includes illuminating the sample and detecting a fluorescent signal, introducing the reaction medium, and illuminating the sample and detecting a second fluorescent signal from the sample. The process further includes processing the two signals to determine which portion of the fluorescent signal is produced solely by the reaction medium.Type: GrantFiled: December 6, 2018Date of Patent: August 18, 2020Assignee: BIOMERIEUXInventors: Bruno Colin, Laurent Drazek, Frederic Pinston
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Patent number: 10655159Abstract: A locating method and system of determining a microorganism concentration of a fluid in a Petri dish is disclosed. The Petri dish includes a culture medium on which a seeding device is rotatable relative to the Petri dish. The seeding device distributes the fluid and includes at least one point of contact with the culture medium. The point of contact is associated with a contact zone.Type: GrantFiled: March 11, 2019Date of Patent: May 19, 2020Assignee: BIOMERIEUXInventors: Laurent Drazek, Corine Fulchiron, Frederic Pinston, Herve Rostaing
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Patent number: 10465225Abstract: A locating method and system of determining a microorganism concentration of a fluid in a Petri dish is disclosed. The Petri dish includes a culture medium on which a seeding device is rotatable relative to the Petri dish. The seeding device distributes the fluid and includes at least one point of contact with the culture medium. The point of contact is associated with a contact zone.Type: GrantFiled: January 20, 2014Date of Patent: November 5, 2019Assignee: BiomerieuxInventors: Laurent Drazek, Corine Fulchiron, Frederic Pinston, Herve Rostaing
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Publication number: 20190270958Abstract: An extraction system includes a support bar including a sample well, a reagent well, at least one washing well, and at least one protection and retention housing; a pipetting element removably mounted on the support bar and extending at least partially into the at least one protection and retention housing; and a filtering and transfer device configured to capture and accumulate microorganisms contained in the sample and transfer the captured and accumulated microorganisms, the filtering and transfer device being removably mounted on the support bar and extending at least partially into the at least one protection and retention housing. The filtering and transfer device includes a hollow body having an elongated shape and including a proximal end portion and a distal end portion; and a filtering element fixed to the distal end portion of the hollow body.Type: ApplicationFiled: November 15, 2017Publication date: September 5, 2019Applicant: BIOMÉRIEUXInventors: Patrick BROYER, Marie-Hélène CHARLES, Jérôme BLAZE, Nadine PERROT, Frédéric PINSTON, Hervé ROSTAING
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Publication number: 20190203258Abstract: A locating method and system of determining a microorganism concentration of a fluid in a Petri dish is disclosed. The Petri dish includes a culture medium on which a seeding device is rotatable relative to the Petri dish. The seeding device distributes the fluid and includes at least one point of contact with the culture medium. The point of contact is associated with a contact zone.Type: ApplicationFiled: March 11, 2019Publication date: July 4, 2019Inventors: Laurent DRAZEK, Corine FULCHIRON, Frederic PINSTON, Herve ROSTAING
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Publication number: 20190107492Abstract: A method and system incorporating a process for analyzing a sample to be tested to determine the presence of or to quantify an analyte in the sample. The process employs a reaction which produces a reaction medium derived from the sample that possesses fluorescence properties, in response to illumination by a light source. The process includes illuminating the sample and detecting a fluorescent signal, introducing the reaction medium, and illuminating the sample and detecting a second fluorescent signal from the sample. The process further includes processing the two signals to determine which portion of the fluorescent signal is produced solely by the reaction medium.Type: ApplicationFiled: December 6, 2018Publication date: April 11, 2019Inventors: Bruno COLIN, Laurent DRAZEK, Frederic PINSTON
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Patent number: 10168284Abstract: A method of analyzing a sample to be tested to determine the presence of or to quantify an analyte in the sample, employing a reaction which produces a reaction medium derived from the sample and which possesses fluorescence properties, the reaction medium being located within a well, the reaction medium and the well forming an analysis assembly which possesses fluorescent properties in response to illumination by a light source producing a light signal, the light source being movable along a surface S1 of the well.Type: GrantFiled: December 23, 2013Date of Patent: January 1, 2019Assignee: BiomerieuxInventors: Bruno Colin, Laurent Drazek, Frédéric Pinston
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Publication number: 20180208958Abstract: A method for detecting a presence or an absence of at least one zone of inhibition, the method including a step consisting in depositing a volume of the sample in liquid form along a deposition zone extending along an axis at the surface of the agar culture medium and a step consisting in depositing a determined amount of a chemical agent at the surface of the agar culture medium, the deposit defining a potential zone of inhibition, the axis of the zone of deposition of the sample intersecting the potential zone of inhibition.Type: ApplicationFiled: July 6, 2016Publication date: July 26, 2018Applicant: BIOMÉRIEUXInventors: Laurent DRAZEK, Agnés DUPONT-FILLARD, Frédéric PINSTON, Hervé ROSTAING
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Publication number: 20170304816Abstract: The present invention relates to a disposable device (100) for amplifying at least one target nucleic acid present in a liquid and biological sample of interest, which consists of a solid body (2), at least one fluid channel (3) connecting an inlet (4), via which all or part of the sample of interest can be drawn up and/or discharged, and an outlet (5), which is itself connected to a means for the drawing up/discharging of the said sample of interest, the fluid channel (3) further comprising from the inlet (4) to the outlet (5): a first compartment (8) containing all or part of the thermostable constituents, a means (15) for mixing the constituents with the sample of interest, a second compartment (9) containing all or part of the non-thermostable constituents, and in addition, at least one zone intended for heating the said sample of interest (6) mixed with the said amplification constituents in order to allow the amplification of the target nucleic acid.Type: ApplicationFiled: July 7, 2017Publication date: October 26, 2017Inventors: Patrick Broyer, Laurent Drazek, Agnès Dupont Filliard, Michel Guy, Frédéric Pinston, Magaly Ponsard-Fillette, Thierry Kollaroczy
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Patent number: 9745612Abstract: The present invention relates to a method of sampling biological material on a reference surface, such as the surface of an agar medium, with the aid of a sampling tool, said method making it possible to steer the displacement of the sampling tool towards the reference surface, from a first position towards a second position, and/or of the reference surface towards the sampling tool, from a first position towards a second position, said second position being a contact position in which the sampling tool and the reference surface are in contact, said method comprising the following steps: a) illuminating the sampling tool in said first position in order to make the sampling tool visible and to project an image of the sampling tool onto the reference surface, b) acquiring an image of both the sampling tool and its image projected onto the reference surface, c) processing the image obtained in step b) in order to determine if, on the processed image, the gap between the sampling tool and its projected image isType: GrantFiled: November 16, 2012Date of Patent: August 29, 2017Assignee: bioMérieuxInventors: Dominique Decaux, Régis Montvernay, Frédéric Pinston
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Patent number: 9726602Abstract: A method for observing biological species on a culture medium contained in a container having at least one translucent face, the method including the steps of: a) directing a light beam onto one portion of the translucent face, so as to define at least one illuminated region and at least one non-illuminated region of the face; and b) acquiring an image of a portion of the surface of the culture medium illuminated by the light beam, the acquisition being carried out through at least one of the non-illuminated regions of the translucent face and along an optical acquisition axis forming a non-zero angle (a) with the direction of propagation of the light beam.Type: GrantFiled: October 28, 2013Date of Patent: August 8, 2017Assignees: Commissariat a L'Energie Atomique et aux Energies Alternatives, BiomerieuxInventors: Mathieu Dupoy, Mathieu Debourdeau, Frédéric Pinston
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Patent number: 9707554Abstract: The present invention relates to a disposable device (100) for amplifying at least one target nucleic acid present in a liquid and biological sample of interest, which consists of a solid body (2), at least one fluid channel (3) connecting an inlet (4), via which all or part of the sample of interest can be drawn up and/or discharged, and an outlet (5), which is itself connected to a means for the drawing up/discharging of the said sample of interest, the fluid channel (3) further comprising from the inlet (4) to the outlet (5): a first compartment (8) containing all or part of the thermostable constituents, a means (15) for mixing the constituents with the sample of interest, a second compartment (9) containing all or part of the non-thermostable constituents, and in addition, at least one zone intended for heating the said sample of interest (6) mixed with the said amplification constituents in order to allow the amplification of the target nucleic acid.Type: GrantFiled: September 17, 2010Date of Patent: July 18, 2017Assignee: bioMérieux, S.A.Inventors: Patrick Broyer, Laurent Drazek, Agnès Dupont Filliard, Michel Guy, Frédéric Pinston, Magaly Ponsard-Fillette, Thierry Kollaroczy
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Publication number: 20170137772Abstract: A method detects the presence or absence of at least one first inhibition zone having a culture of biological particles on a culture medium in the presence of a chemical agent. The method of detection has a first step of seeding the culture medium with the biological particles, a second step in which the culture medium receives the chemical agent, a third step of incubation of the culture medium, and a fourth step of measurement of the first inhibition zone of the culture medium, which includes a first phase of taking an image of the first inhibition zone by ombroscopy.Type: ApplicationFiled: June 29, 2015Publication date: May 18, 2017Applicant: bioMérieuxInventors: Laurent DRAZEK, Frédéric PINSTON
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Patent number: 9606046Abstract: An imaging system for generating images of biological samples having a surface, the system comprising: a sample support for supporting a biological sample in use; a plurality of illumination sources, the plurality of illumination sources being arranged around the sample support and each adapted to illuminate the biological sample, in use, from a different direction; an image capture device for capturing illumination which has impinged on the biological sample to thereby form an image of the sample; wherein at least one of the illumination sources direction is not perpendicular to the surface of the sample.Type: GrantFiled: May 7, 2012Date of Patent: March 28, 2017Assignee: bioMérieuxInventors: Dominique Decaux, Frédéric Pinston, Denis Desseree, Guillaume Boissier, Corine Fulchiron, Lorette Lapierre, Lorène Allano, Léontine Jacolin, Christophe Tachier
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Patent number: 9576181Abstract: A method for defining an isolation area around an object of interest in a cell culture vessel, the method comprising the steps of: —obtaining one or more images of the cell culture vessel using one or more of a plurality of illumination sources, each illumination source being capable of illuminating the vessel from a different direction; —selecting an image or combination of images for further processing; —applying a circular object detection transformation to identify one or more objects of interest being substantially circular objects in the cell culture vessel, which circular objects of interest are representative of isolated colonies in the cell culture vessel and determining the center of an object of interest; —applying a binarizing step to obtain a binarized image of the object of interest and other objects, wherein the center of the binarized image corresponds to the center of the object of interest; —iteratively forming concentric circles with increasing radius, wherein the concentric circles are cenType: GrantFiled: November 7, 2013Date of Patent: February 21, 2017Assignees: BioMerieux, Commissariat a l'Energie Atomique et aux Energies AlternativesInventors: Loréne Allano, Guillaume Sutra, Lorette Munoz, Corine Fulchiron, Dominique Decaux, Frédéric Pinston
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Publication number: 20160216212Abstract: A method of analysing a sample to be tested to determine the presence of or to quantify an analyte in the sample, employing a reaction which produces a reaction medium derived from the sample and which possesses fluorescence properties, the reaction medium being located within a well, the reaction medium and the well forming an analysis assembly which possesses fluorescent properties in response to illumination by a light source producing a light signal, the light source being movable along a surface S1 of the well.Type: ApplicationFiled: December 23, 2013Publication date: July 28, 2016Inventors: BRUNO COLIN, LAURENT DRAZEK, FRÉDÉRIC PINSTON
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Patent number: 9400242Abstract: A method for enhancing an image of a biological sample, which biological sample has been grown in a vessel on a culture medium.Type: GrantFiled: May 7, 2012Date of Patent: July 26, 2016Assignees: bioMérieux, Commissariat à l'Energie Atomique et aux Energies AlternativesInventors: Lorène Allano, Léontine Jacolin, Dominique Decaux, Frédéric Pinston, Denis Desseree, Guillaume Boissier, Christophe Tachier, Corine Fulchiron, Lorette Lapierre, Guillaume Sutra