Patents by Inventor Frédéric Saudou

Frédéric Saudou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTISENSE OLIGONUCLEOTIDES FOR THEIR USE IN AN ANTI-CANCER TREATMENT
    Publication number: 20240158797
    Abstract: An antisense oligonucleotides having the ability to decrease the expression level of the huntingtin protein in glioma cells, for their use in sensitizing the cells to an anti-cancer treatment.
    Type: Application
    Filed: March 18, 2022
    Publication date: May 16, 2024
    Applicants: UNIVERSITÉ GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE
    Inventors: Sandrine HUMBERT, Fabienne AGASSE, Frédéric SAUDOU, Kassem RAYANE
  • ACYL-PROTEIN THIOESTERASE INHIBITOR FOR THE TREATMENT AND/OR PREVENTION OF HUNTINGTON'S DISEASE
    Publication number: 20230181574
    Abstract: Disclosed is an inhibitor of the acyl-protein thioesterase APT1, ML-348, of formula A: for use in the treatment and/or prevention of a disease or disorder in a subject in need thereof. In particular the inhibitor is for use in the treatment and/or prevention of a neurodegenerative disease or disorder, particularly Huntington's disease. Also disclosed is a pharmaceutical composition including at least the APT1 inhibitor and at least one pharmaceutically acceptable excipient. The inhibitor or composition is intended for use as a medicament. Furthermore, the inhibitor or composition is intended for use in the treatment and/or prevention of a disease or disorder related to impaired intracellular trafficking between the endoplasmic reticulum and the Golgi apparatus and between the latter and the plasma membrane.
    Type: Application
    Filed: February 21, 2020
    Publication date: June 15, 2023
    Inventors: Frederic SAUDOU, Amandine VIRLOGEUX
  • TREATMENT OF MECP-2 ASSOCIATED DISORDERS
    Publication number: 20130316961
    Abstract: The invention relates to the use of cystamine, cysteamine, or a salt thereof, or of calcineurin inhibitors for treating a MeCP2-associated disorder such as Rett syndrome.
    Type: Application
    Filed: October 24, 2011
    Publication date: November 28, 2013
    Applicants: UNIVERSITÉ D'AIX-MARSEILLE, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (Institut National de la Santé et de la Recherche Médicale)
    Inventors: Jean-Christophe Roux, Laurent Villard, Frédéric Saudou
  • Use of Huntingtin Protein for the Diagnosis and the Treatment of Cancer
    Publication number: 20110039789
    Abstract: The present invention relates to new methods of treatment of cancer, in particular of breast cancer, and methods of screening of compounds useful in the treatment of cancer. The present invention further provides new prognostic and/or diagnostic markers in human cancer.
    Type: Application
    Filed: August 13, 2010
    Publication date: February 17, 2011
    Applicants: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Sandrine Humbert, Frederic Saudou, John McGuire, Anne Vincent Salomon
  • Method For Treating Huntington's Disease by Inhibiting Dephosphorylation of Huntingtin at S421
    Publication number: 20080300178
    Abstract: The present invention relates to a method for treating patients having Huntington's disease by a drug increasing the phosphorylation of huntingtin at position S421, thereby decreasing the polyQ-huntingtin-induced toxicity.
    Type: Application
    Filed: January 18, 2007
    Publication date: December 4, 2008
    Applicants: Insitut Curie, Centre National De La Recherche Scientifique
    Inventors: Raul Pardo, Sandrine Humbert, Frederic Saudou