Patents by Inventor Frances G. Crawford

Frances G. Crawford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying MHC-presented peptide epitopes for T cells
    Publication number: 20040110253
    Abstract: Described are three basic components: (1) methods for the display of functional MHC molecules with covalently attached antigenic peptides on the surface of baculovirus and baculovirus infected insect cells; (2) methods for the identification and physical isolation of baculovirus or baculovirus infected insect cells bearing a displayed MHC/peptide combination that is recognized by a particular T cell antigen receptor; and (3) methods for producing libraries of baculovirus or baculovirus infected insect cells displaying a particular MHC molecule and many different potential antigenic peptides.
    Type: Application
    Filed: August 13, 2003
    Publication date: June 10, 2004
    Inventors: John W. Kappler, Frances G. Crawford, Philippa Marrack
  • Specific hybridoma cell line and monocolonal antibodies produced from such specific hybridoma cell line and method of using such monoclonal antibodies to detect carcinoembryonic antigens
    Patent number: 4873313
    Abstract: A specific hybridoma cell line produces monoclonal antibodies which are effective in detecting carcinoembryonic antigens (CEA). The specific hydribome line and monoclonal antibodes are designated as T84.66-A3.1-H11. The monoclonal antibodies are preferably applied to tissues and fluids to detect the degree of binding of such monoclonal antibodies to such carcinoembryonic antigens.
    Type: Grant
    Filed: April 18, 1985
    Date of Patent: October 10, 1989
    Assignee: Beckman Research Institute of City of Hope
    Inventors: Frances G. Crawford, John E. Shively, Charles W. Todd, Y. H. Joy Yang