Patents by Inventor Frances Yen-Potin

Frances Yen-Potin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LSR receptor, its activity, its cloning, and its applications to the diagnosis, prevention and/or treatment of obesity and related risks or complications
    Publication number: 20040077051
    Abstract: The present invention relates to a new complex receptor polypeptide LSR (Lipolysis Stimulated Receptor), characterized by its functional activities, the cloning of the cDNAs complementary to the messenger RNAs encoding each of the subunits of the multimeric complex, vectors and transformed cells, methods of diagnosis and of selection of compounds which can be used as medicament for the prevention and/or treatment of pathologies and/or of pathogeneses such as obesity and anorexia, hyperlipidemias, atherosclerosis, diabetes, hypertension, and more generally the various pathologies associated with abnormalities in the metabolism of cytokines.
    Type: Application
    Filed: August 27, 2003
    Publication date: April 22, 2004
    Applicant: Genset S.A.
    Inventors: Bernard Bihain, Lydie Bougueleret, Frances Yen-Potin
  • OBG3 globular head and uses thereof
    Publication number: 20040067881
    Abstract: The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. A compound, globular OBG3, has been identified that reduces weight gain in animals. This compound should be effective for reducing body mass and for treating obesity-related diseases and disorders. These obesity-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
    Type: Application
    Filed: November 1, 2002
    Publication date: April 8, 2004
    Applicant: Genset S.A.
    Inventors: Joachim Fruebis, Mary Ruth Erickson, Frances Yen-Potin, Bernard Bihain
  • LSR receptor, activity, cloning, and uses for diagnosing, preventing and/or treating obesity and related risks or complications
    Patent number: 6635431
    Abstract: The present invention relates to a new complex receptor polypeptide LSR (Lipolysis Stimulated Receptor), characterized by its functional activities, the cloning of the cDNAs complementary to the messenger RNAs encoding each of the subunits of the multimeric complex, vectors and transformed cells, methods of diagnosis and of selection of compounds which can be used as medicament for the prevention and/or treatment of pathologies and/or of pathogeneses such as obesity and anorexia, hyperlipidemias, atherosclerosis, diabetes, hypertension, and more generally the various pathologies associated with abnormalities in the metabolism of cytokines.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: October 21, 2003
    Assignees: Genset, S.A., Institute National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Bernard Bihain, Lydie Bougueleret, Frances Yen-Potin
  • APM1 biallelic markers and uses thereof
    Publication number: 20030165967
    Abstract: The invention provides novel APM1 genomic sequences, polypeptides, antibodies, and polynucleotides including biallelic markers derived from the APM1 locus. Primers hybridizing to regions flanking these biallelic markers are also provided. This invention also provides polynucleotides and methods suitable for genotyping a nucleic acid containing sample for one or more biallelic markers of the invention. Additionally, the invention provides methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype. Further, the invention provides diagnostic methods for early detection of obesity-related disorders.
    Type: Application
    Filed: February 28, 2003
    Publication date: September 4, 2003
    Applicant: Genset, S.A.
    Inventors: Lydie Bougueleret, Bernard Bihain, Blake Denison, Frances Yen-Potin
  • APM1 biallelic markers and uses thereof
    Patent number: 6582909
    Abstract: The invention provides novel APM1 genomic sequences, polypeptides, antibodies, and polynucleotides including biallelic markers derived from the APM1 locus. Primers hybridizing to regions flanking these biallelic markers are also provided. This invention also provides polynucleotides and methods suitable for genotyping a nucleic acid containing sample for one or more biallelic markers of the invention. Additionally, the invention provides methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype. Further, the invention provides diagnostic methods for early detection of obesity-related disorders.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: June 24, 2003
    Assignee: Genset, S.A.
    Inventors: Lydie Bougueleret, Bernard Bihain, Blake Denison, Frances Yen-Potin
  • OBG3 globular head and uses thereof for decreasing body mass
    Patent number: 6579852
    Abstract: The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. A compound, globular OBG3, has been identified that reduces weight gain in animals. This compound should be effective for reducing body mass and for treating obesity-related diseases and disorders. These obesity-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: June 17, 2003
    Assignee: Genset S.A.
    Inventors: Joachim Fruebis, Mary Ruth Erickson, Frances Yen-Potin, Bernard Bihain
  • Apolipoprotein A-IV-related protein: polypeptide, polynucleotide sequences and biallelic markers thereof
    Publication number: 20030032783
    Abstract: The invention provides the genomic sequence of AA4RP, AA4RP cDNAs and AA4RP polypeptides. Further the invention provides polynucleotides including biallelic markers derived from the AA4RP gene and from genomic regions flanking the gene. This invention also provides polynucleotides and methods suitable for genotyping a nucleic acid containing sample for one or more biallelic markers of the invention. Further, the invention provides methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype. The invention also relates to diagnostic methods for determining whether an individual is at risk of developing a lipid metabolism related disorder and/or a liver related disorder, or whether said individual suffers from a lipid metabolism related disorder and/or a liver related disorder as a result of a polymorphism in the AA4RP gene.
    Type: Application
    Filed: April 25, 2001
    Publication date: February 13, 2003
    Inventors: Frances Yen-Potin, Blake Denison, Jean Baptiste Dumas Milne Edwards, Bernard Bihain, Barbara Bour, Aymeric Duclert, Lydie Bougueleret
  • Lipoprotein-regulating medicaments
    Publication number: 20020165154
    Abstract: Methods and pharmaceutical compositions useful for modulating lipoprotein levels in vivo. The invention stems from the discovery that activity of the Lipolysis Stimulated Receptor (LSR) can be inhibited or enhanced by exogenous agents, including polypeptides.
    Type: Application
    Filed: January 29, 2002
    Publication date: November 7, 2002
    Inventors: Bernard Bihain, Lydie Bougueleret, Frances Yen-Potin
  • Lipoprotein-regulating medicants
    Publication number: 20020151498
    Abstract: Methods and pharmaceutical compositions useful for modulating lipoprotein levels in vivo. The invention stems from the discovery that activity of the Lipolysis Stimulated Receptor (LSR) can be inhibited or enhanced by exogenous agents, including polypeptides.
    Type: Application
    Filed: February 5, 2002
    Publication date: October 17, 2002
    Applicant: GENSET, S.A.
    Inventors: Bernard Bihain, Lydie Bougueleret, Frances Yen-Potin
  • OBG3 globular head and uses thereof for decreasing body mass
    Publication number: 20020091080
    Abstract: The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. A compound, globular OBG3, has been identified that reduces weight gain in animals. This compound should be effective for reducing body mass and for treating obesity-related diseases and disorders. These obesity-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
    Type: Application
    Filed: July 19, 2001
    Publication date: July 11, 2002
    Inventors: Joachim Fruebis, Mary Ruth Erickson, Frances Yen-Potin, Bernard Bihain
  • Lipoprotein-regulating medicaments
    Patent number: 6344441
    Abstract: Methods and pharmaceutical compositions useful for modulating lipoprotein levels in vivo. The invention stems from the discovery that activity of the Lipolysis Stimulated Receptor (LSR) can be inhibited or enhanced by exogenous agents, including polypeptides.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: February 5, 2002
    Assignee: Genset
    Inventors: Bernard Bihain, Lydie Bougueleret, Frances Yen-Potin