Patents by Inventor Francesca Cordeiro

Francesca Cordeiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Diagnosis
    Publication number: 20230047141
    Abstract: The invention relates to methods for determining the stage of a disease, particularly an ocular neurodegenerative disease such as Alzheimer's, Parkinson's, Huntington's and glaucoma, comprising the steps of identifying the status of microglial cells in the retina and relating that status to disease stage. Methods for identifying cells in the eye are also provided, as are labelled markers and the use thereof.
    Type: Application
    Filed: January 22, 2021
    Publication date: February 16, 2023
    Inventors: Maria Francesca Cordeiro, John Maddison
  • Composition
    Publication number: 20210220270
    Abstract: The present invention provides a pharmaceutical composition comprising a peroxisome proliferator activated receptor (PPAR) modulator and an polymeric nanocarrier component, wherein the polymeric nanocarrier component is capable of solubilising the PPAR modulator in an aqueous medium and, wherein in the polymeric nanocarrier component is a micelle forming non-ionic surfactant. Uses of the same in therapy are also provided.
    Type: Application
    Filed: June 27, 2019
    Publication date: July 22, 2021
    Inventor: Maria Francesca CORDEIRO
  • COMPOSITION COMPRISING VEGF ANTAGONISTS AND A CATIONIC PEPTIDE AND USES THEREOF
    Publication number: 20210145921
    Abstract: The invention relates compositions comprising a small cationic peptide and a VEGF antagonist, and the use of such compositions in the treatment or prevention of conditions characterised by VEGF dysfunction, for example vasculoproliferative conditions, particularly in the eye.
    Type: Application
    Filed: August 23, 2018
    Publication date: May 20, 2021
    Inventors: Francesca CORDEIRO, Benjamin Michael DAVIS, Ljuban GRGIC, Satyanarayana SOMAVARAPU
  • Carrier comprising a vitamin E derivative
    Patent number: 9545392
    Abstract: A pharmaceutical composition is provided comprising a vitamin E derivative, an anionic phopholipid-binding protein, an anionic phospholipid and a sterol. Also provided is a method for preparing a composition for delivering a cargo to a subject comprising a) forming liposomes from a vitamin E derivative, an anionic phospholipid-binding protein such as annexin, an anionic phospholipid such as phosphatidylserine and a sterol; and b) encapsulating the cargo in the liposomal composition.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: January 17, 2017
    Assignee: UCL BUSINESS PLC
    Inventors: Francesca Cordeiro, Stephen Moss, Katy Coxon, James Duggan
  • Pharmaceutical composition comprising a Vitamin E derivative and a cell death marker
    Patent number: 9539203
    Abstract: The invention relates to a carrier for delivering agents to the posterior region of the eye, the carrier comprising a Vitamin E derivative, especially tocopherol. The carrier may also comprise a cell death marker, such as an annexin.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: January 10, 2017
    Assignee: UCL BUSINESS PLC
    Inventors: Francesca Cordeiro, Stephen Moss
  • Quantifying cell death
    Patent number: 9014457
    Abstract: The invention relates to methods of diagnosis, particularly methods of staging and diagnosing neurodegenerative diseases using images of cell death in the eye.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: April 21, 2015
    Assignee: UCL Business PLC
    Inventors: Stephen Moss, Maria Francesca Cordeiro, Steven Dakin
  • Composition comprising a cell death marker and a wavelength-optimized label
    Patent number: 8771645
    Abstract: The invention relates to the use of a cell death marker labelled with a wavelength-optimised label for identifying cell death in the eye. Suitable cell death markers are the Annexins and fragments and derivatives thereof. The invention also relates to a pharmaceutical composition comprising a cell death marker labelled with a wavelength-optimised label and a method for monitoring cell death in the eye using a cell death marker labelled with a wavelength-optimised label.
    Type: Grant
    Filed: December 15, 2008
    Date of Patent: July 8, 2014
    Assignee: UCL Business PLLC
    Inventors: Francesca Cordeiro, Stephen Moss, Frederick Fitzke
  • QUANTIFYING CELL DEATH
    Publication number: 20120243769
    Abstract: The invention relates to methods of diagnosis, particularly methods of staging and diagnosing neurodegenerative diseases using images of cell death in the eye.
    Type: Application
    Filed: November 5, 2010
    Publication date: September 27, 2012
    Applicant: UCL BUSINESS PLC
    Inventors: Stephen Moss, Maria Francesca Cordeiro, Steven Dakin
  • CARRIER
    Publication number: 20120115771
    Abstract: A pharmaceutical composition is provided comprising a vitamin E derivative, an anionic phopholipid-binding protein, an anionic phospholipid and a sterol. Also provided is a method for preparing a composition for delivering a cargo to a subject comprising a) forming liposomes from a vitamin E derivative, an anionic phospholipid-binding protein such as annexin, an anionic phospholipid such as phosphatidylserine and a sterol; and b) encapsulating the cargo in the liposomal composition.
    Type: Application
    Filed: March 29, 2010
    Publication date: May 10, 2012
    Applicant: UCL BUSINESS PLC
    Inventors: Francesca Cordeiro, Stephen Moss, Katy Coxon, James Duggan
  • MARKER
    Publication number: 20100284922
    Abstract: The invention relates to the use of a cell death marker labelled with a wavelength-optimised label for identifying cell death in the eye. Suitable cell death markers are the Annexins and fragments and derivatives thereof. The invention also relates to a pharmaceutical composition comprising a cell death marker labelled with a wavelength-optimised label and a method for monitoring cell death in the eye using a cell death marker labelled with a wavelength-optimised label.
    Type: Application
    Filed: December 15, 2008
    Publication date: November 11, 2010
    Applicant: UCL Business plc
    Inventors: Francesca Cordeiro, Stephen Moss, Frederick Fitzke
  • CARRIER
    Publication number: 20100278747
    Abstract: The invention relates to a carrier for delivering agents to the posterior region of the eye, the carrier comprising a Vitamin E derivative, especially tocopherol. The carrier may also comprise a cell death marker, such as an annexin.
    Type: Application
    Filed: December 19, 2008
    Publication date: November 4, 2010
    Applicant: UCL BUSINESS PLC
    Inventors: Francesca Cordeiro, Stephen Moss