Abstract: A system for controlling nonlinear plants which may be effected with gain scheduled feedback controllers. Several linear sub-controllers having various gains may be put together as one unit. The overall controller may be changed by switching from one sub-controller to another according to an exogenous or endogenous parameter. The signal to the switch may reflect operational ranges of the plant occurring at certain times and indicate the gain desired from the system relative to the output and input signals of the plant at those times. The advantages of the present approach may include a guarantee of nominal and robust stability both global and local, a permitting of the use of control structures that are familiar to industrial practitioners, and no requirement of advanced mathematical techniques for its implementation.

Abstract: A multivariable controller that models the interaction between groups of sensors and groups of actuators during the operation of an engine. By accounting for the interactive effects that a group of actuators has on a sensor or group of sensors, improved system performance may be achieved. When emission sensors are used, such as NOX and/or PM sensors, the multivariable controller may help control the various engine actuators to reduce emissions of the engine.

Abstract: Methods and systems for controlling a diesel engine using a combined fuel and air-side controller are disclosed. An illustrative method may include the steps of providing a combined fuel and air-side controller adapted to coordinate both the fuel and air-side control of an engine, sensing one or more parameters, and outputting a fuel profile signal and one or more air-side control signals for controlling at least a part of the fuel-side and at least a part of the air-side of the engine. By centrally coordinating both the fuel and air-side control of the engine, the system can be configured to anticipate future fuel and/or air-side needs of the engine, thus improving system response, performance, and/or emissions.

Abstract: Systems and methods for controlling an engine using feedback from one or more sensors are disclosed. An illustrative control system for controlling a diesel engine may include one or more post-combustion sensors adapted to directly sense at least one constituent of exhaust gasses emitted from the exhaust manifold of the engine, and a state observer for estimating the internal state of the diesel engine based on feedback signals received from the post-combustion sensors and from subsequent use of the estimated state in a controller that sends the actuator setpoints. The post-combustion sensors can be configured to directly measure emissions such as oxides of nitrogen (NOx) and/or particulate matter (PM) within the exhaust stream, and provide such information to a state observer that, in turn, updates an internal dynamical state based on these measurements.

Abstract: Methods and systems for controlling a diesel engine using a combined fuel and air-side controller are disclosed. An illustrative method may include the steps of providing a combined fuel and air-side controller adapted to coordinate both the fuel and air-side control of an engine, sensing one or more parameters, and outputting a fuel profile signal and one or more air-side control signals for controlling at least a part of the fuel-side and at least a part of the air-side of the engine. By centrally coordinating both the fuel and air-side control of the engine, the system can be configured to anticipate future fuel and/or air-side needs of the engine, thus improving system response, performance, and/or emissions.

Abstract: Systems and methods for using pedal position and/or pedal change rate in the fuel side and/or air side control of an engine. By knowing the pedal position and/or pedal rate, an engine controller may anticipate future fuel and/or air needs of the engine, and adjust the fuel profile and/or air profile to meet those anticipated needs. This may help improve the responsiveness, performance and emissions of the engine.

Abstract: The present invention relates to the use of a TNF Receptor together with a steroid hormone to produce a pharmaceutical composition for the treatment of lethal bacterial and viral infections as well as autoimmune and inflammatory diseases. It also relates to said pharmaceutical compositions for the simultaneous separate or sequential use of its active ingredients for the above specified treatment. In particular, it relates to the use of TBP-1, together with dehydroepiandrosterone (DHEA) or its metabolites to produce a pharmaceutical composition for the treatment of septic shock.

Abstract: A multivariable controller that models the interaction between groups of sensors and groups of actuators during the operation of an engine. By accounting for the interactive effects that a group of actuators has on a sensor or group of sensors, improved system performance may be achieved. When emission sensors are used, such as NOX and/or PM sensors, the multivariable controller may help control the various engine actuators to reduce emissions of the engine.

Abstract: The present invention relates to the use of a TNF Receptor together with a steroid hormone to produce a pharmaceutical composition for the treatment of lethal bacterial and viral infections as well as autoimmune and inflammatory diseases. It also relates to said pharmaceutical compositions for the simultaneous, separate or sequential use of its active ingredients for the above specified treatment. In particular, it relates to the use of TBP-1 together with dehydroepiandrosterone (DHEA) or its metabolites to produce a pharmaceutical composition for the treatment of septic shock.

Abstract: The present invention refers to the use of Compound B as angiogenic agent in combination with human growth factors.

Abstract: The present invention refers to the use of Compound B as angiogenic agent in combination with human growth factors.

Abstract: Tumor necrosis factor antagonists are administered in therapeutically effective doses to treat and/or prevent endometriosis. The antagonists of this invention typically are selected among various classes of molecules but preferably are soluble TNF receptors. The antagonists are useful for the regression of endometriotic lesions and, if combined with other active ingredients, for amelioration of related disorders, like infertility.

Abstract: Tumor necrosis factor antagonists are administered in therapeutically effective doses to treat and/or prevent endometriosis. The antagonists of this invention typically are selected from among several classes but preferably are soluble TNF receptors. The antagonists are useful for the regression of endometriotic lesions and, if combined with other active ingredients, for amelioration of related disorders, like infertility.

Abstract: The present invention refers to the use of Compound B as angiogenic agent in combination with human growth factors.

Abstract: The present invention relates to the use of a TNF Receptor together with a steroid hormone to produce a pharmaceutical composition for the treatment of lethal bacterial and viral infections as well as autoimmune and inflammatory diseases. It also relates to said pharmaceutical compositions for the simultaneous, separate or sequential use of its active ingredients for the above specified treatment. In particular, it relates to the use of TBP-1 together with dehydroepiandrosterone (DHEA) or its metabolites to produce a pharmaceutical composition for the treatment of septic shock.

Abstract: The present invention relates to the use of Component B as cicatrizant, in particular in the treatment of wounds, ulcers and other traumatic lesions to any of the tissues in the body.

Abstract: The toxic effects caused by anthraquinone drugs, particularly by antitumor anthraquinone drugs, are inhibited or reduced by administering Orgotein in a quantity sufficient to inhibit or reduce the superoxide radicals which are produced by the above mentioned drugs.

Abstract: The association of a fibrinolytic agent and of a diffusion factor has been shown very useful in the treatment of myocardial infarction. It has been shown that it is very useful to administer urokinase and hyaluronidase in the quantity ratio of at least 8 to 1, the quantity of each compound being expressed in the appropriate international units.