Abstract: The present invention relates to methods for assessing one's risk for suffering from severe COVID or long COVID symptoms. Also provided are methods for reducing the risk of developing severe COVID and/or long COVID symptoms.

Abstract: The present invention resides in the discovery that altered abundance of fungal species in the gut and feces of both fecal microbiota transplantation (FMT) donors and recipients may influence the outcome of FMT treatment. Thus, novel methods are provided for identifying subjects as suitable donor or recipients for FMT, for assessing the likelihood of FMT treatment success, and for enhancing FMT treatment efficacy. Also provided are kits and compositions for FMT with enhanced efficacy.

Abstract: Methods are provided for treating metabolic diseases by way of modulating recipients' gastrointestinal tract microorganism profile such as by fecal microbiota transplantation (FMT) treatment. Also provided are methods for assessing a patient's risk of developing obesity and/or related metabolic diseases. Further provided are kits and compositions for use in these methods.

Abstract: Provided are methods for treating symptoms of autism spectrum disorder (ASD) in a human child. Methods for determining risk for A SD in human children, methods for assessing developmental age of children and for treating children in need thereof, kits and compositions for use in these methods are also provided.

Abstract: Methods and compositions for treating and/or preventing a bacterial infection in a subject are provided, in which the subject is administered a fecal sample obtained from a donor subject via fecal microbiota transplantation (FMT). The fecal sample contains bacteriophages that target the bacteria causing the infection. In some embodiments, the fecal sample containing the bacteriophages can be obtained from a donor subject who previously had the same infection but is now cured.

Abstract: An adaptive radio frequency including an input, an output, at least one fixed passive inductor and at least one variable active inductor connected between the input and the output.

Abstract: Methods are provided for treating COVID-19 patients to facilitate their recovery from the disease as well as for prognosis of severity of COVID-19 among patients who have been infected by SARS-CoV-2. Also provided are kits and compositions for use in these methods.

Abstract: A probiotic composition comprising Bifidobacterium bifidum and Bifidobacterium longum, and may further comprising Bifidobacterium adolescentis and Lactobacillus rhamnosus is provided. A prebiotic composition comprising xylooligosaccharide, galactooligosaccharide, and corn dietary fiber, and a dietary composition comprising the probiotic composition and the prebiotic composition are provided. Use of the foregoing compositions in the preparation of a dietary product or a drug for assisting in preventing and/or treating a pathogen infection of an individual, enhancing the therapeutic effect of a pathogen infection of an individual, improving the immunity of an individual, or balancing the gut microecology of an individual is provided. The foregoing compositions can be used in patients suffering from COVID-19.

Abstract: The present invention provides for compositions and methods for treating long COVID symptoms or reducing the risk of developing such symptoms.

Abstract: Certain microorganism species in a composition for use in fecal microbiota transplantation (FMT), including fecal material obtained from an FMT donor, can affect the outcome of FMT treatment such as regulating the bodyweight and cholesterol level in FMT recipients. Thus, methods are provided for identifying subjects as suitable donor to optimize FMT outcome and for pretreating donors and/or recipients for optimized FMT outcome. Also provided are kits and compositions for improving FMT outcome, including for bodyweight and/or cholesterol reduction.

Abstract: Methods are provided for identifying subjects as suitable donor or recipients for FMT, for assessing the likelihood of FMT treatment success, and for enhancing FMT treatment efficacy. Also provided are kits and compositions for FMT with enhanced efficacy.

Abstract: The present disclosure provides compositions and methods related to the modulation of the inflammation response activated by a host's immune system. In particular, the present disclosure provides novel inhibitors of proteins that exhibit pro-inflammatory activity (e.g., RIPK1, RIPK3, ZBP1, TRIF, CUL1, SKP1, and NF-?B, among others), as well as corresponding therapeutic compositions and methods of treatment using these inhibitors.

Abstract: Systems and methods for fault tolerant content delivery. A request is received from a user for customized content on the network, the request for customized content comprising an identifier for the content and identification information. The request is forwarded from the user for the customized content over the network. Generic content corresponding to the customized content is stored in a cache for future use. The generic content is sent to the user if no customized content is received in response to the forwarded request from the user.

Abstract: A circuit of an output stage of a push-pull driver having dynamic biasing may include a stacked configuration of field effect transistors (PFETs) having a first PFET, a second PFET, and a third PFET, whereby the first PFET is connected to a first supply voltage, the third PFET is connected to an output of a switchable voltage bias generator circuit, and the second PFET is electrically connected between the first PFET and the third PFET. A transmission gate may be connected to a second supply voltage, whereby the transmission gate electrically connects the second supply voltage to an electrical connection between the first PFET and the second PFET based on a first operating state for preventing a voltage breakdown condition associated with the stacked configuration of PFETs. The third PFET is bias controlled via the switching of the output of the switchable voltage bias generator circuit.

Abstract: A circuit of an output stage of a push-pull driver having dynamic biasing may include a stacked configuration of field effect transistors (PFETs) having a first PFET, a second PFET, and a third PFET, whereby the first PFET is connected to a first supply voltage, the third PFET is connected to an output of a switchable voltage bias generator circuit, and the second PFET is electrically connected between the first PFET and the third PFET. A transmission gate may be connected to a second supply voltage, whereby the transmission gate electrically connects the second supply voltage to an electrical connection between the first PFET and the second PFET based on a first operating state for preventing a voltage breakdown condition associated with the stacked configuration of PFETs. The third PFET is bias controlled via the switching of the output of the switchable voltage bias generator circuit.

Abstract: Methods and systems to provide supplemental content to a user who is viewing video or other content. The user's device (through which he will access the video) then provides an identifier of that video to a server or other computing facility. Here, the video identifier is used to identify supplemental content that corresponds to the user's video. The supplemental content is then provided to the user device for the user's consumption. The supplemental content may be structured in such a way that pieces of the supplemental content are accessible at particular points in the video. The piece(s) of the supplemental content available at a particular point in the video will be related to one or more objects that are present at this point. This allows a user to access one or more pieces of supplemental content in a context-specific manner, at a point in the video where the piece(s) of supplemental content are relevant.

Abstract: Methods and systems to improve the efficiency of a content delivery system. A local distribution node is introduced to the network, between the content provider and the end user device (i.e., the leaf node). The local distribution node is responsible for servicing a localized subset of the leaf nodes that would otherwise be serviced by a conventional server of the content delivery system. Requests for content are received at the local distribution node from leaf nodes, and content is received at the local distribution node for transmission to the leaf node(s). Content may be cached at the local distribution node to allow faster service of subsequent requests for this content. Caching may also be used to make the channel surfing process more efficient. If demand is high, a leaf node may be promoted to serve as an additional local distribution node. Leaf nodes may also share content among themselves.

Abstract: Methods and systems to improve the efficiency of a content delivery system. A local distribution node is introduced to the network, between the content provider and the end user device (i.e., the leaf node). The local distribution node is responsible for servicing a localized subset of the leaf nodes that would otherwise be serviced by a conventional server of the content delivery system. Requests for content are received at the local distribution node from leaf nodes, and content is received at the local distribution node for transmission to the leaf node(s). Content may be cached at the local distribution node to allow faster service of subsequent requests for this content. Caching may also be used to make the channel surfing process more efficient. If demand is high, a leaf node may be promoted to serve as an additional local distribution node. Leaf nodes may also share content among themselves.

Abstract: Methods and systems to improve the efficiency of a content delivery system. A local distribution node is introduced to the network, between the content provider and the end user device (i.e., the leaf node). The local distribution node is responsible for servicing a localized subset of the leaf nodes that would otherwise be serviced by a conventional server of the content delivery system. Requests for content are received at the local distribution node from leaf nodes, and content is received at the local distribution node for transmission to the leaf node(s). Content may be cached at the local distribution node to allow faster service of subsequent requests for this content. Caching may also be used to make the channel surfing process more efficient. If demand is high, a leaf node may be promoted to serve as an additional local distribution node. Leaf nodes may also share content among themselves.

Abstract: Methods and systems to indicate events of interest to a user. IN an embodiment, an event processor queries each of a plurality of event data sources, then receives event data from one or more event data source. The event processor then identifies an event to be indicated to a user device based on the event data. The identified event to the user through a user device. The event processor may receive, via the user device, feedback regarding the identified event. This feedback may be used to train future event identification. The event processor may be implemented at a computing device that is remote from the user, such as a server. Alternatively, the event processor may be implemented internal to the user device.