Patents by Inventor Francis E. Kenny

Francis E. Kenny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vascular magnetic resonance imaging agent comprising nanoparticles
    Patent number: 5314679
    Abstract: The preparation and isolation of biodegradable superparamagnetic MR imaging contrast agents for the vascular compartment is described. These aggregates are comprised of individual biodegradable superparamagnetic metal oxide crystals which aggregates have an overall mean diameter less than about 4000 angstroms. The preferred vascular imaging contrast agent is comprised of aggregates of iron oxide crystals having an overall mean diameter less than about 500 angstroms. These contrast agents may be associated with a macromolecular species, which assist, among other things, in the preparation of these extremely small materials, and may be dispersed or dissolved in a physiologically acceptable medium. Preferred media also stabilize the materials against further aggregation even under harsh sterilization conditions.
    Type: Grant
    Filed: December 22, 1992
    Date of Patent: May 24, 1994
    Assignee: Advanced Magnetics Inc.
    Inventors: Jerome M. Lewis, Edward T. Menz, Francis E. Kenny, Ernest V. Groman, Lee Josephson
  • Vascular magnetic imaging method and agent comprising biodegradeable superparamagnetic metal oxides
    Patent number: 5055288
    Abstract: The preparation and isolation of biodegradable superparamagnetic MR imaging contrast agents for the vascular compartment is described. These aggregates are comprised of individual biodegradable superparamagnetic metal oxide crystals which aggregates have an overall mean diameter less than about 4000 angstroms. The preferred vascular imaging contrast agent is comprised of aggregates of iron oxide crystals having an overall mean diameter less than about 500 angstroms. These contrast agents may be associated with a macromolecular species, which assist, among other things, in the preparation of these extremely small materials, and may be dispersed or dissolved in a physiologically acceptable medium. Preferred media also stabilize the materials against further aggregation even under harsh sterilization conditions.
    Type: Grant
    Filed: August 16, 1988
    Date of Patent: October 8, 1991
    Assignee: Advanced Magnetics, Inc.
    Inventors: Jerome M. Lewis, Edward T. Menz, Francis E. Kenny, Ernest V. Groman, Lee Josephson