Patents by Inventor Francis Egiste Joseph Paolucci

Francis Egiste Joseph Paolucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the immunoassay of antithrombin III activated by a glycosaminoglycan, corresponding monoclonal antibodies and method for obtaining them
    Patent number: 5891647
    Abstract: A method that assays activated antithrombin III (AT III) is useful for monitoring the effect in vivo of an agent that activates AT III. It involves the steps of contacting AT III with a solution sample containing the agent, wherein the agent is a sulfated glycosaminoglycan or a sulfated oligosaccharide, followed by contacting the sample with i) a first monoclonal antibody that preferentially binds AT III activated by the agent, as opposed to binding native AT III, and ii) a second monoclonal antibody that preferentially binds denatured AT III as opposed to either AT III activated by the agent or native AT III.
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: April 6, 1999
    Assignee: Pasteur Sanofi Diagnostics
    Inventors: Jean-Claude Lormeau, Renee Georgette Milleblandine, Francis Egiste Joseph Paolucci, Bernard Pau