Patents by Inventor Francisco Dean Toste

Francisco Dean Toste has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Palladium and boron co-catalyzed addition of oxygen nucleophiles to vinyl epoxides
    Patent number: 6307067
    Abstract: Nucleophilic oxygen species, such as primary alcohols, carboxylates, and water, are added to vinyl epoxides in a highly regioselective and enantioselective manner, providing a convenient route to enantiomerically enriched 1,2-diols and oxygen-containing heterocycles. The reaction employs a chiral Pd(0) complex and a borane or borate as co-catalysts Also described are similar additions of nitrogen nucleophiles, and the addition of carbonates to vinyl epoxides using a chiral Pd(0) catalyst.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: October 23, 2001
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Ernest John McEachern, Francisco Dean Toste, Barry Martin Trost