Patents by Inventor Francisco Lopez-Jimenez
Francisco Lopez-Jimenez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240081653Abstract: Systems, methods, devices, and techniques for estimating a heart disease prediction of a mammal. An electrocardiogram (ECG) procedure is performed on a mammal, and a computer system obtains ECG data that describes results of the ECG over a period of time. The system provides a predictive input that is based on the ECG data to a predictive model, such as a neural network or other machine-learning model. In response, the predictive model processes the input to generate an estimated heart disease predictive characteristic of the mammal. The system outputs the estimated heart disease prediction of the mammal for presentation to a user.Type: ApplicationFiled: October 31, 2023Publication date: March 14, 2024Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventors: Itzhak Zachi Attia, Paul A. Friedman, Francisco Lopez-Jimenez, Suraj Kapa
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Publication number: 20230089991Abstract: Systems, methods, devices, and techniques for estimating a heart disease prediction of a mammal. An electrocardiogram (ECG) procedure is performed on a mammal, and a computer system obtains ECG data that describes results of the ECG over a period of time. The system provides a predictive input that is based on the ECG data to a predictive model, such as a neural network or other machine-learning model. In response, the predictive model processes the input to generate an estimated heart disease predictive characteristic of the mammal. The system outputs the estimated heart disease prediction of the mammal for presentation to a user.Type: ApplicationFiled: November 7, 2022Publication date: March 23, 2023Inventors: Itzhak Zachi Attia, Paul A. Friedman, Francisco Lopez-Jimenez, Suraj Kapa
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Publication number: 20220218289Abstract: Apparatuses and methods are provided to predict or diagnose an ischemic event, such as a stroke or a transient ischemic attack (TIA). A machine-learning model such as a neural network is generated that allows for recognition of an ECG consistent with an ischemic event. A system is trained and used to process a recording of ECG data from a patient to generate a prediction indicating a likelihood that the patient will experience a stroke. In other examples, a system is trained and used to process a recording of ECG data from a patient and detect an ischemic event for the patient who did not appear to have such an ischemic event.Type: ApplicationFiled: March 31, 2022Publication date: July 14, 2022Applicant: Mayo Foundation for Medical Education and ResearchInventors: Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Peter A. Noseworthy, Suraj Kapa, Francisco Lopez-Jimenez
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Publication number: 20220189634Abstract: Provided herein are methods, systems, and computer program products for the detection of pulmonary hypertension comprising receiving voltage-time data of a plurality of leads of an electrocardiograph of a subject; generating a feature vector from the voltage-time data; providing the feature vector to a pretrained learning system; and receiving from the pretrained learning system an indication of the presence or absence of pulmonary hypertension in the subject.Type: ApplicationFiled: October 13, 2021Publication date: June 16, 2022Inventors: Tyler Wagner, Samir Awasthi Awasthi, Venkataramanan Soundararajan, Murali Aravamudan, Corinne Carpenter, Katherine Carlson, Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Surai Kapa, Francisco Lopez-Jimenez, Hilary M. Dubrock
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Patent number: 11317872Abstract: Apparatuses and methods are provided to predict or diagnose an ischemic event, such as a stroke or a transient ischemic attack (TIA). A machine-learning model such as a neural network is generated that allows for recognition of an ECG consistent with an ischemic event. A system is trained and used to process a recording of ECG data from a patient to generate a prediction indicating a likelihood that the patient will experience a stroke. In other examples, a system is trained and used to process a recording of ECG data from a patient and detect an ischemic event for the patient who did not appear to have such an ischemic event.Type: GrantFiled: December 14, 2018Date of Patent: May 3, 2022Assignee: Mayo Foundation for Medical Education and ResearchInventors: Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Peter A. Noseworthy, Suraj Kapa, Francisco Lopez-Jimenez
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Publication number: 20210401347Abstract: Systems and methods for assessing the condition of a heart of an individual. A system obtains electrocardiogram (ECG) data that describes a result of an ECG of the individual. The ECG data can be provided to a machine-learning model, which processes the data and generates an output indicative of the condition of the heart. The output relates to a level of troponin in a bloodstream of the individual. The system can then provide the output of the machine-learning model to a post-processing resource.Type: ApplicationFiled: June 24, 2021Publication date: December 30, 2021Inventors: Paul A. Friedman, Itzhak Zachi Attia, Allan S. Jaffe, Suraj Kapa, Francisco Lopez-Jimenez, Yader B. Sandoval Pichardo
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Publication number: 20210361217Abstract: Systems, methods, devices, and other techniques for estimating the age and sex of a person through analysis of an electrocardiogram (ECG) recording for the person. Some aspects include recording an ECG of a person, processing data representing the ECG with an age-estimation neural network to generate an estimated age of the person, and outputting an indication of the estimated age of the person. Other aspects include processing the ECG with a sex prediction neural network to generate a predicted sex of the person and outputting an indication of the predicted sex of the person.Type: ApplicationFiled: January 11, 2019Publication date: November 25, 2021Applicant: Mayo Foundation for Medical Education and ResearchInventors: Itzhak Zachi Attia, Paul A. Friedman, Suraj Kapa, Francisco Lopez-Jimenez
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Publication number: 20200397313Abstract: Systems, methods, devices, and techniques for estimating an ejection-fraction characteristic of a mammal. An electrocardiogram (ECG) procedure is performed on a mammal, and a computer system obtains ECG data that describes results of the ECG over a period of time. The system provides a predictive input that is based on the ECG data to an ejection-fraction predictive model, such as a neural network or other machine-learning model. In response, the ejection-fraction predictive model processes the input to generate an estimated ejection-fraction characteristic of the mammal. The system outputs the estimated ejection-fraction characteristic of the mammal for presentation to a user.Type: ApplicationFiled: October 4, 2018Publication date: December 24, 2020Applicant: Mayo Foundation for Medical Education and ResearchInventors: Itzhak Zachi Attia, Paul A. Friedman, Francisco Lopez-Jimenez, Suraj Kapa
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Publication number: 20200069416Abstract: A replacement heart valve device including a stent member that is to be compressible and expandable, and a dry valve directly sutured to the stent member. The dry valve includes two to four leaflets made of a treated pericardium tissue that has been gas sterilized.Type: ApplicationFiled: April 10, 2019Publication date: March 5, 2020Inventors: David PANIAGUA, R. David FISH, Eduardo INDUNI, Carlos MEIJA, Francisco LOPEZ-JIMENEZ
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Publication number: 20190209300Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.Type: ApplicationFiled: March 31, 2017Publication date: July 11, 2019Inventors: David PANIAGUA, R. FISH, Eduardo INDUNI, Carlos MEIJA, Francisco LOPEZ-JIMENEZ
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Publication number: 20190183431Abstract: Apparatuses and methods are provided to predict or diagnose an ischemic event, such as a stroke or a transient ischemic attack (TIA). A machine-learning model such as a neural network is generated that allows for recognition of an ECG consistent with an ischemic event. A system is trained and used to process a recording of ECG data from a patient to generate a prediction indicating a likelihood that the patient will experience a stroke. In other examples, a system is trained and used to process a recording of ECG data from a patient and detect an ischemic event for the patient who did not appear to have such an ischemic event.Type: ApplicationFiled: December 14, 2018Publication date: June 20, 2019Applicant: Mayo Foundation for Medical Education and ResearchInventors: Itzhak Zachi Attia, Paul A. Friedman, Samuel J. Asirvatham, Peter A. Noseworthy, Suraj Kapa, Francisco Lopez-Jimenez
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Publication number: 20170265997Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.Type: ApplicationFiled: March 31, 2017Publication date: September 21, 2017Inventors: David PANIAGUA, R. David FISH, Eduardo INDUNI, Carlos MEIJA, Francisco LOPEZ-JIMENEZ
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Patent number: 8308797Abstract: The present invention comprises a percutaneously implantable replacement heart valve device and a method of making same. The replacement heart valve device comprises a stent member made of stainless steel or self-expanding nitinol, a biological tissue artificial valve means disposed within the inner space of the stent member. An implantation and delivery system having a central part which consists of a flexible hollow tube catheter that allows a metallic wire guide to be advanced inside it. The endovascular stented-valve is a glutaraldehyde fixed bovine pericardium which has two or three cusps that open distally to permit unidirectional blood flow.Type: GrantFiled: July 10, 2004Date of Patent: November 13, 2012Assignee: Colibri Heart Valve, LLCInventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. David Fish
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Patent number: 8109995Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.Type: GrantFiled: August 8, 2008Date of Patent: February 7, 2012Assignee: Colibri Heart Valve LLCInventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. David Fish
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Publication number: 20090030511Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of gluteraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.Type: ApplicationFiled: August 8, 2008Publication date: January 29, 2009Inventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. David Fish
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Publication number: 20050113910Abstract: The present invention comprises a percutaneously implantable replacement heart valve device and a method of making same. The replacement heart valve device comprises a stent member made of stainless steel or self-expanding nitinol, a biological tissue artificial valve means disposed within the inner space of the stent member. An implantation and delivery system having a central part which consists of a flexible hollow tube catheter that allows a metallic wire guide to be advanced inside it. The endovascular stented-valve is created from a glutaraldehyde fixed biocompatible tissue material which has two or three cusps that open distally to permit unidirectional blood flow.Type: ApplicationFiled: July 10, 2004Publication date: May 26, 2005Inventors: David Paniagua, Eduardo Induni, Carlos Mejia, Francisco Lopez-Jimenez, R. Fish