Patents by Inventor Franco Delle Monache

Franco Delle Monache has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chalcones and esters thereof with antiproliferative activity in uterus, ovary and breast tumors
    Patent number: 5808137
    Abstract: The present invention relates to the use of some natural or synthetic chalcones and the esters thereof with straight or branched aliphatic acids, saturated and unsaturated, containing up to 22 carbon atoms in the therapy and prevention of the uterus, ovary and breast tumors, as well as the formulations containing them. Chalcones such as isocordoin, cordoin, 2-hydroxyderricin, 2',4'-dihydroxychalcone, 4,2',4'-trihydroxychalcone have a marked affinity to the estrogen receptors of type II and an antiproliferative activity on uterus, ovary and breast tumor cell lines. These molecules proved to be useful both in therapy and in the prevention of such tumors.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: September 15, 1998
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Salvatore Mancuso, Franco Delle Monache