Abstract: The present invention relates to a formulation sized for injection comprising a biodegradable polyesteramide co-polymer comprising at least a diol of bicyclic-1,4:3,6-dianhydrohexitol and analgesics for use in the treatment of arthritic disorders. More specific the invention relates to a formulation comprising injectable microparticle according to claim 1 wherein the polyesteramide co-polymer further comprises a diacid, a diol different from bicyclic-1,4:3,6-dianhydrohexitol and at least two different amino-acids. The formulation is used to treat pain or inflammation in a patient comprising administering to said patient a therapeutically effective amount of the formulation once or twice a year.

Abstract: It is an object of the invention is a fuel cell system architecture provides a good weight distribution, improved trunk space without reducing the security against front-end and rear end collision.

Abstract: It is an object of the invention is a fuel cell system architecture provides a good weight distribution, improved trunk space without reducing the security against front-end and rear end collision.

Abstract: A system and method for reducing the nitrogen oxides found in the exhaust produced by a vehicle engine, the system comprising a NOx trap and a first adding means for adding a reducing agent to the exhaust gas. The first adding means is positioned downstream of the engine and either upstream of or within the NOx trap.

Abstract: The present invention relates to a formulation sized for injection comprising a biodegradable polyesteramide co-polymer comprising at least a diol of bicyclic-1,4:3,6-dianhydrohexitol and analgesics for use in the treatment of arthritic disorders. More specific the invention relates to a formulation comprising injectable microparticle according to claim 1 wherein the polyesteramide co-polymer further comprises a diacid, a diol different from bicyclic-1,4:3,6-dianhydrohexitol and at least two different amino-acids. The formulation is used to treat pain or inflammation in a patient comprising administering to said patient a therapeutically effective amount of the formulation once or twice a year.

Abstract: A method of controlling pressure of a fuel system of a hybrid vehicle including an engine fed with fuel stored in a tank made of plastics material, and an electric motor, the method including, when the engine is stopped, relaxing pressure inside the fuel tank in full or in part after a given safety duration and as a function of at least one stress accumulation parameter, each stress accumulation parameter being associated with an element of the fuel system and being defined by information concerning temperature, information concerning exposure duration, and information concerning a level of stress on the element.

Abstract: The present invention relates to a process for the manufacturing of a multilayer construct comprising layering at least one drug loaded film from which each film comprises a polymer and at least a drug manufactured by the steps of dissolving the polymer in an organic solvent, mixing the dissolved polymer with the drug, laminating the mixture between at least two polymeric sheets, whereby at least one sheet is permeable to the organic solvent, removing the sheets to provide the drug loaded film, layering the drug loaded film and fusing the drug loaded films into a multilayer construct. The present invention also relates to the multilayer construct obtainable by the process according to the present invention and to the use of the multilayer construct in ophthalmology, cardiovascular, pain management, musculoskeletal, cancer treatment or in vaccine delivery.

Abstract: A method of controlling pressure of a fuel system of a hybrid vehicle including an engine fed with fuel stored in a tank made of plastics material, and an electric motor, the method including, when the engine is stopped, relaxing pressure inside the fuel tank in full or in part after a given safety duration and as a function of at least one stress accumulation parameter, each stress accumulation parameter being associated with an element of the fuel system and being defined by information concerning temperature, information concerning exposure duration, and information concerning a level of stress on the element.

Abstract: This invention concerns an autonomus media termination centric signaling architecture that takes advantage of both a peer-to-peer signaling protocol such as the SIP and Master/Slave protocols such as MGCP/Megaco/NCS. More specifically, the present invention describes an Internet telephony agent comprising a user agent call manager including a user agent stack for communication with a peer, a master stack, and a multi-protocol call manager for communication between the user agent stack and the master stack; and a media termination coupled to the user agent call manager including a hardware manager, and a slave stack for communication between the master stack and the hardware manager. The user call manager and the media termination of Internet telephony agent may be tightly coupled or loosely coupled, allowing the inter-operation of the Internet telephony agent with both SIP and MGCP/Megaco/NCS media terminations.