Abstract: The present invention is related to dalcetrapib or dalcetrapib-thiol, or a combination thereof for use in the prevention and/or treatment of disorders characterized by inefficient transport and delivery of oxygen to peripheral tissues. The invention in particular relates to pharmaceutical formulations, regimens, methods of treatment and uses thereof.

Abstract: The present invention is related to a combination useful in the prevention and/or treatment of red blood cell disorders, in particular, acute and chronic complications associated with red blood cell dysfunction, increased red blood cell cholesterol and decreased plasma levels of lipophilic antioxidant (sickle cell disease, thalassemia, diabetes). The invention in particular relates to pharmaceutical formulations, regimens, methods of treatment and uses thereof.

Abstract: The present invention relates to an immunogenic composition for fish comprising nodavirus virus-like particles (VLPs) formed with nodavirus capsid protein assembly, for use as a vaccine. This composition is suitable for administration to fish via the intramuscular or intraperitoneal route, or by bath and/or via the oral route. The invention also relates to the use of such VPLs for the manufacturing of a vaccine for treating or preventing fish against a nodavirus infection. Fish farming baths and concentrates comprising the nodavirus VLP composition, as well as fish farming methods, are also encompassed in the present invention.