Patents by Inventor Francois Lescure
Francois Lescure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220087945Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.Type: ApplicationFiled: November 11, 2021Publication date: March 24, 2022Applicant: Da VolterraInventors: Francois LESCURE, Jean DE GUNZBURG
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Patent number: 11202761Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.Type: GrantFiled: July 26, 2018Date of Patent: December 21, 2021Assignee: DA VOLTERRAInventors: Francois Lescure, Jean De Gunzburg
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Publication number: 20180369156Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.Type: ApplicationFiled: July 26, 2018Publication date: December 27, 2018Applicant: Da VolterraInventors: Francois LESCURE, Jean DE GUNZBURG
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Patent number: 10052288Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.Type: GrantFiled: July 5, 2017Date of Patent: August 21, 2018Assignee: DA VOLTERRAInventors: Francois Lescure, Jean De Gunzburg
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Patent number: 9968562Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.Type: GrantFiled: February 23, 2011Date of Patent: May 15, 2018Assignee: DA VOLTERRAInventors: Francois Lescure, Jean De Gunzburg
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Publication number: 20170296478Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.Type: ApplicationFiled: July 5, 2017Publication date: October 19, 2017Inventors: Francois Lescure, Jean De Gunzburg
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Patent number: 9366490Abstract: In the field of feeding ammunition to a firearm there is disclosed a flexible chute including successive sections (2) linked by portions of walls (111, 112, 131) at the transverse faces thereof and including at least one tubular section (2) of axis G with a first portion of wall (111, 112) integral with one of the two transverse faces thereof and a second portion (131) of wall integral with the other transverse face, characterized in that the projections of these portions of wall, perpendicular to a transverse plane of the section, are at least partially separate.Type: GrantFiled: September 19, 2013Date of Patent: June 14, 2016Assignee: ETAT FRANCAIS REPRESENTE PAR LE DELEGUE GENERAL POUR L'ARMEMENTInventor: Jean-Francois Lescure
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Publication number: 20150233658Abstract: In the field of feeding ammunition to a firearm there is disclosed a flexible chute including successive sections (2) linked by portions of walls (111, 112, 131) at the transverse faces thereof and including at least one tubular section (2) of axis G with a first portion of wall (111, 112) integral with one of the two transverse faces thereof and a second portion (131) of wall integral with the other transverse face, characterized in that the projections of these portions of wall, perpendicular to a transverse plane of the section, are at least partially separate.Type: ApplicationFiled: September 19, 2013Publication date: August 20, 2015Applicant: ETAT FRANCAIS REPRESENTE PAR LE DELEGUE GENERAL POUR L'ARMEMENTInventor: Jean-Francois Lescure
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Publication number: 20130052269Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.Type: ApplicationFiled: February 23, 2011Publication date: February 28, 2013Applicant: DA VOLTERRAInventors: Francois Lescure, Jean De Gunzburg
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Publication number: 20120058936Abstract: Oral drug delivery formulations which specifically administer antibacterial agents to the ileum, caecum, and/or the colon, without significant administration elsewhere in the gastrointestinal tract, are disclosed. The formulations include, as actives, a combination of a macrolide or aminoglysoside, or quinolone antibacterial and an anti-Gram-negative lipopeptide (polymyxin) antibacterial agent or other peptide antibacterials effective against Gram-negative bacteria. The formulations can be used to treat infections or unwanted colonization in the colon, and to provide effective decontamination of the colonic flora from unwanted or potentially pathogenic bacteria.Type: ApplicationFiled: March 12, 2010Publication date: March 8, 2012Applicants: ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS, DA VOLTERRA, UNIVERSITE PARIS DIDEROT - PARIS 7Inventors: Antoine Andremont, Jean De Gunzburg, Francois Lescure
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Patent number: 6420468Abstract: Nanoparticles formed from a random polymer of at least one compound of formula (I) in which A represents a group or a group; R1 and R2, identical or different, represent a linear or branched C1-C6 alkyl group; n=1, 2, 3, 4 or 5, having a diameter of less than 500 nm and an average molecular mass (Mw) between about 8000 and 100000, the nanoparticles being formed from homogeneous molecular species, and optionally containing a biologically active material.Type: GrantFiled: January 29, 2001Date of Patent: July 16, 2002Assignee: VirsolInventors: Nicole Bru-Magniez, Xavier Guillon, Pascal Breton, Patrick Couvreur, François Lescure, Claude Roques-Carmes, Gérard Riess
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Publication number: 20010006989Abstract: The invention relates to a method for the preparation of nanoparticles formed from a random polymer of at least one compound of formula (I) 1Type: ApplicationFiled: January 29, 2001Publication date: July 5, 2001Applicant: VIRSOLInventors: Nicole Bru-Magniez, Xavier Guillon, Pascal Breton, Patrick Couvreur, Francois Lescure, Claude Roques-Carmes, Gerard Riess
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Patent number: 6211273Abstract: The invention relates to a method for the preparation of nanoparticles formed from a random polymer of at least one compound of formula (I) in which A represents a group or a group; R1 and R2, identical or different, represents a linear or branched C1-C6 alkyl group; n=1, 2, 3, 4 or 5, characterised in that the monomer is dissolved beforehand in a water-miscible aprotic organic solvent forming, with the polymerisation medium, a non-solvent mixture of the polymer formed.Type: GrantFiled: April 16, 1999Date of Patent: April 3, 2001Assignee: VirsolInventors: Nicole Bru-Magniez, Xavier Guillon, Pascal Breton, Patrick Couvreur, François Lescure, Claude Roques-Carmes, Gérard Riess
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Patent number: 5604326Abstract: A striker device for a firearm of the type having a loading chamber for a munition includes a detonator cap provided with a percussion cap and a translationally movable assembly comprised of a striker equipped with a striker tip and associated with a part or valve in which the striker is axially guided and that is itself guided in axial displacement in a passage of a striker body located to the rear of the loading chamber. The striker and valve are respectively mounted by the front and rear faces of striker body and joined to each other by a removable connector of the bayonet type.Type: GrantFiled: December 21, 1994Date of Patent: February 18, 1997Assignee: Giat IndustriesInventor: Jean-Francois Lescure
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Patent number: 5535661Abstract: A mechanism for transmitting torque between a drive shaft and an output shaft including a mechanical control element which causes an angular phase offset between the shafts. The mechanism includes a coupling element joining the shafts together. The coupling element includes a member capable of angular travel relative to a first of the shafts which, when mechanically controlled, provides the angular phase offset and control of the travel causing mutual drive of the shafts.Type: GrantFiled: December 27, 1994Date of Patent: July 16, 1996Assignee: Giat IndustriesInventors: Jean-Francois Lescure, Julien Jimenez
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Patent number: 5353678Abstract: An automatic gun for firing telescoped cylindrical ammunition, the gun comprising a sleeve for supporting a barrel, a breech, and a rear box which are all rigidly connected together by beams, the gun including a chamber disposed between the breech and the barrel and mounted to swing by pivoting about an eccentric shaft, and further including means carried by the breech and the rear box to feed ammunition to the chamber.Type: GrantFiled: May 20, 1993Date of Patent: October 11, 1994Assignee: Giat IndustriesInventors: Marc Rochelle, Jean-Francois Lescure, Julien Jimenez
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Patent number: 5231243Abstract: Control and safety device for an externally powered automatic weapon include at least one rotor driven by a motor and have a stop cooperating with a locking part. The device has both a detent lever to control firing and a second lever subjected to the action of a rotating finger driven by the recoil of the weapon. The detent lever and the second lever are connected to the locking part by a system of slides and links which automatically stop the rotor by way of the locking part if ammunition should malfunction.Type: GrantFiled: June 18, 1992Date of Patent: July 27, 1993Assignee: Giat IndustriesInventor: Jean-Francois Lescure