Abstract: Substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division, also are disclosed.

Abstract: Substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division, also are disclosed.

Abstract: A fresh market tomato harvester comprises a leading knife for severing tomato plants, an inclined ascending conveyor for transporting the cut plants upwardly onto the harvester, a shaker bed for removing the tomatoes from the vines, transverse cross conveyors for receiving the tomatoes after they have been shaken from the vines and for transporting them laterally outward, longitudinally extending side sorting belts for receiving the tomatoes and transporting them rearwardly past workers who remove stems and other foreign matter as well as overripe fruit, sizing conveyors for automatically classifying the tomatoes by size and rejecting undersized tomatoes, and, optionally, a washing station for removing gummy matter and dust. The elevator carries arcuate tines, each of which is covered with surgical tubing which extends beyond the end of the metal tine to provide a resilient yielding structure.