Patents by Inventor Frank A. Laski

Frank A. Laski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mammalian suppressor genes
    Patent number: 4687737
    Abstract: A method of suppressing a nonsense codon in a gene in a mammalian cell by preparing an oligonucleotide primer having a mismatched anticodon region corresponding to the nonsense codon; preparing a DNA template for production of a tRNA molecule enabling the insertion of an amino acid when the nonsense codon is translated; forming a suppressor gene from said template and primer by site specific mutagenesis; and transforming the suppressor gene into the cell.
    Type: Grant
    Filed: July 2, 1985
    Date of Patent: August 18, 1987
    Assignee: Massachusetts Institute of Technology
    Inventors: Phillip A. Sharp, Mario R. Capecchi, Uttam L. RajBhandary, Frank A. Laski