Patents by Inventor Frank Guo-Bin Wang

Frank Guo-Bin Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted therapeutic agent release devices and methods of making and using the same
    Patent number: 8101200
    Abstract: Generally, the present invention provides devices and methods for delivering high, efficacious concentrations of therapeutic agents, i.e., medicaments such as drugs, antibiotics, etc., to specific sites in a patient's body, such as tumors and infected lesions. In one aspect of the present invention there are provided devices to accomplish the aforesaid delivery of therapeutic agents and methods to accomplish the delivery by positioning a device in the body using minimally invasive techniques such as, for example, catheterization or via trochar. The devices may contain a carrier substrate and a coating on the substrate. The carrier substrate provides structural integrity to the device and the coating thereon contains at least one layer of polymeric material containing one or more medicaments. Optionally, there may be a non-medicated binder coat between the carrier substrate and the medicated polymer layer. The medicated polymer layer may contain a hydrophilic/hydrophobic polymer composition.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: January 24, 2012
    Inventors: Richard J. Whitbourne, Daniel Hullihen, Michael R. Violante, Frank Guo-Bin Wang, Xianping Zhang
  • Targeted therapeutic agent release devices and methods of making and using the same
    Publication number: 20020018795
    Abstract: Generally, the present invention provides devices and methods for delivering high, efficacious concentrations of therapeutic agents, i.e., medicaments such as drugs, antibiotics, etc., to specific sites in a patient's body, such as tumors and infected lesions. In one aspect of the present invention there are provided devices to accomplish the aforesaid delivery of therapeutic agents and methods to accomplish the delivery by positioning a device in the body using minimally invasive techniques such as, for example, catheterization or via trochar. The devices may contain a carrier substrate and a coating on the substrate. The carrier substrate provides structural integrity to the device and the coating thereon contains at least one layer of polymeric material containing one or more medicaments. Optionally, there may be a non-medicated binder coat between the carrier substrate and the medicated polymer layer. The medicated polymer layer may contain a hydrophilic/hydrophobic polymer composition.
    Type: Application
    Filed: April 12, 2001
    Publication date: February 14, 2002
    Inventors: Richard J. Whitbourne, Daniel Hullihen, Michael R. Violante, Frank Guo-Bin Wang, Xianping Zhang