Abstract: The differential adiabatic compensation calorimeter comprises sample and reference containers, sample and reference temperature sensors connected back-to-back, in series, sample and reference compensating heaters coupled to the sample and reference containers, and a temperature-controlled chamber. In this differential adiabatic mixing and reaction calorimeter, the sample heat-sink heat loss to the sample container is compensated so that the exothermic reaction is conducted in an adiabatic state, resulting in an undistorted adiabatic process gaining the highest adiabatic temperature rise that corresponds to the theoretical value and an experimentally measured time to maximum rate value. The calorimeter is designed for measuring the time-resolved adiabatic temperature rise, the rate of temperature rise, the time to maximum temperature peak and time to maximum rate of an exothermic chemical reaction.