Abstract: A hermetically sealed container and a medicament bearing insert assembly therefor are disclosed. The medicament bearing insert assembly is protected by a severable overcap. A pocket within the insert assembly is provided with a pierceable membrane. Rupture of the membrane by a built-in plunger causes the medicament to drop out of the pocket and into the container where it is mixed with the container contents.

Abstract: A hermetically sealed container and a medicament bearing insert assembly therefor are disclosed. The medicament bearing insert assembly is protected by a severable overcap. A pocket within the insert assembly is provided with a pierceable membrane. Rupture of the membrane by a built-in plunger causes the medicament to drop out of the pocket and into the container where it is mixed with the container contents.

Abstract: A sterilizing method is provided for use with a container filling machine having components defining passages through which a fluid product flows. In one method aspect, sterilizing steam is passed through the components unitl the components have been sterilized. As the system cools and the steam condenses, the system is pressurized with gas to prevent the internal pressure in the system from decreasing below the ambient atmospheric pressure. In a further method aspect, the sterilizing process is controlled in response to sensing the temperature of one or more of the components. In yet another aspect, a common source of sterilizing steam is provided for being directed into the product filling system and simultaneously into an associated process gas supply system to sterilize both systems generally concurrently in a single pass.