Patents by Inventor Frank R. Gonzales

Frank R. Gonzales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
    Patent number: 5710029
    Abstract: Methods and kits for relating initial amounts of target nucleic acids present in a sample to target-specific amplification products. It has been discovered that the transcription-mediated amplification system is capable of producing a quantitative relationship between target input and target-specific output. Further, the present invention relates to methods for carefully controlling this relationship resulting in an unexpectedly high degree of reproducability. Also described are useful methods for extending the dynamic range of transcription-based amplification systems.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 20, 1998
    Assignee: Gen-Probe Incorporated
    Inventors: Thomas Brendan Ryder, Karen W. Shannon, Daniel Louis Kacian, Richard C. Harvey, Sherrol H. McDonough, Frank R. Gonzales, Maria R. Castillo, Elizabeth R. Billyard, Nancy Lau Liu Shen
  • Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
    Patent number: 5705365
    Abstract: Methods and kits for relating initial amounts of target nucleic acids present in a sample to target-specific amplification products. It has been discovered that the transcription-mediated amplification system is capable of producing a quantitative relationship between target input and target-specific output. Further, the the present invention relates to methods for carefully controlling this relationship resulting in an unexpectedly high degree of reproducability. Also described are useful methods for extending the dynamic range of transcription-based amplification systems.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 6, 1998
    Assignee: Gen-Probe Incorporated
    Inventors: Thomas Brendan Ryder, Karen W. Shannon, Daniel Louis Kacian, Richard C. Harvey, Sherrol H. McDonough, Frank R. Gonzales, Maria R. Castillo, Elizabeth R. Billyard, Nancy Lau Liu Shen