Abstract: A swaging system for attaching surgical needles to sutures and testing the attachment strength includes a frame, a bottom swaging die mounted on the frame, and a top swaging die mounted on the frame and being moveable up and down along a swaging axis that is aligned with the bottom swaging die. The bottom swaging die includes a hinge mechanism with a bottom plate mounted to the frame and a top plate overlying the bottom plate. The top and bottom plates are pivotally connected for enabling the top plate to pivot relative to the bottom plate. The bottom swaging die includes a swaging tool that extends toward the top swaging die along the swaging axis, and a load cell disposed between the top and bottom plates for monitoring load. The system includes a control system having one or more pull test programs stored therein for conducting pull tests on armed surgical needles to determine if the armed surgical needles are acceptable or unacceptable.

Abstract: The application relates to means, which derive from TAL effectors and TALENs. The structure of the means of the application is especially adapted for partial or full deletion of at least one DNA tandem repeat, more particularly for partial or full deletion of at least one DNA tandem repeat in a double-stranded DNA, more particularly for partial or full deletion of at least one DNA tandem repeat, which is contained in a double-stranded DNA and, which forms a complex secondary structure, such as a hairpin, a triple helix or a tetraplex secondary structure. The means of the application are notably useful in the treatment and/or prevention and/or palliation of a disease or disorder involving at least one DNA tandem repeat, such as DM1, SCA8, SCA12, HDL2, SBMA, HD, DRPLA, SCA1, SCA2, SCA3, SCA6, SCA7, SCA17, PSACH, DM2, SCA10, SPD1, OPMD, CCD, HPE5, HFG syndrome, BPES, EIEE1, FRAXA, FXTAS and FRAXE.

Abstract: A self-centering handle assembly is provided for a vehicle door. The handle assembly includes a pivoting handle base coupled to the vehicle door at a pivot axis, and includes a front face having a first and second opposing ends. The first and seconds ends are configured for a selective pivotal movement in opposite directions about the pivot axis. First and second drive arms are provided extending a distance from a rear portion of the handle base and configured for coordinated movement with the respective first and second ends of the handle base. A bell crank is provided, coupled to the handle assembly, and configured to rotate about a second pivot axis. Rotation of the bell crank is driven by movement of the first and second drive arms. A biasing member is in contact with the bell crank and urges the bell crank to a return to a self-centering, rest position.

Abstract: A flush mounted handle assembly for a vehicle is provided, operable with both power and manual modes of opening and closing a slide door. The flush mounted handle assembly may include a case configured to be fixed in a recess of a power slide door of a vehicle. A dual-directional handle base may be provided, pivotally coupled to the case. The handle base may have a first end and a second opposing end. The first and seconds ends may be configured for a selective pivotal movement in opposite directions about a pivot axis. A bell crank may be provided, coupled to the case, and configured to rotate upon engagement with the handle base in order to actuate a switch assembly and to coordinate different operations of the power slide door.

Abstract: A flush mounted handle assembly is provided for a power slide door of a vehicle. The handle assembly includes a case fixed to the door, the case defining a rear wall and opposing side portions. A bell crank is provided configured to coordinate selective power and manual operational modes of the assembly. The assembly includes a handle base having a first end and a second opposing end. The first and seconds ends are configured for selective pivotal movement in opposite directions about a fixed pivot axis to engage the bell crank. A pair of weighted paddles is provided, each rotatable about an axis independent from the handle base axis. One or more paddle biasing members is provided to bias the weighted paddles against the handle base, minimizing movement of the handle base in the manual operational mode upon an impact, or during an unintended rotational movement of the handle base.

Abstract: Systems and methods are provided for preventing the unintentional operation of a flush mounted handle assembly for a power slide door of a vehicle. A dual-directional handle base may be provided, pivotally coupled to a case fixed in a recess of a power slide door of a vehicle. The handle base may have a first end and a second opposing end. The first and seconds ends may be configured for a selective pivotal movement in opposite directions about a pivot axis. A bell crank may be provided, coupled to the case, and configured to rotate upon engagement with the handle base in order to actuate a switch assembly sending a signal to an ECU. Methods may include determining, at the ECU, that the signal was not transmitted as a result of a vehicle impact. After such determination, the method includes activating operation of the power slide door.

Abstract: Executing a command on an optimal smart device. One aspect of the present invention provides a method for executing a command. The method includes: receiving a command at a plurality of smart devices; determining a score for each smart device of the plurality of smart devices; communicating the score between each smart device of the plurality of smart devices; comparing the score between each smart device of the plurality of smart devices; and executing the command at one smart device of the plurality of smart devices based on comparing the score between each smart device.

Abstract: Total knee replacements for hinged knee implants include a tibial member, a femoral member, a hinge assembly having a laterally extending axle configured to hingedly attach the femoral member to the tibial member, and a lock mechanism in communication with the hinge assembly. The lock mechanism is configured to (i) lock the femoral member in alignment with the tibial member for a full extension or other defined stabile walking configuration to thereby allow an arthrodesis or stiff knee gait and (ii) unlock to allow the femoral and tibial members to pivot relative to each other for flexion or bending when not ambulating.

Abstract: One or more systems and/or methods for determining a query date range and/or searching a content corpus are provided. A set of content items (e.g., digital images, videos, etc.), associated with an event, may be identified from a content corpus. The set of content items may be evaluated to identify temporal features (e.g., digital time stamps) for the set of content items. A query date range for the event may be determined based upon the temporal features (e.g., users may capture photos that are related to Christmas from December 4th to December 27th). In an example, responsive to receiving a search query, associated with the event, the search query may be adjusted based upon the query date range to create an adjusted search query. The content corpus may be searched using the adjusted search query to create search query results for the search query.

Abstract: Methods and systems for predicting content consumption are provided herein. An application log of a user, comprising a user's application data, and a viewing log of the user, comprising the user's viewing data (e.g., television programs watched by the user), may be evaluated over a time period to construct a model. The model may comprise a correlation between the viewing log and the application log during the time period (e.g., what applications the user interacts with while watching a program). Second application data, regarding application usage of a second user, may be extracted. The model may be applied to the second application data to identify an expected viewing action of the second user (e.g., what program the second user is likely to watch during the time period based upon applications used by the second user). The second user may be provided with content related to the expected viewing action.

Abstract: Total joint replacements for implants include a first member configured to attach to a first bone, a second member configured to reside in an adjacent second hone and a locking mechanism. The locking mechanism is configured to (i) lock the first and second members in alignment for full extension or other defined stabilized configuration and (ii) unlock to allow the first and second members to pivot relative to each other for flexion or bending.

Abstract: Total joint replacements for implants include a first member configured to attach to a first bone, a second member configured to reside in an adjacent second bone and a locking mechanism. The locking mechanism is configured to (i) lock the first and second members in alignment for full extension or other defined stabilized configuration and (ii) unlock to allow the first and second members to pivot relative to each other for flexion or bending.

Abstract: Executing a command on an optimal smart device. One aspect of the present invention provides a method for executing a command. The method includes: receiving a command at a plurality of smart devices; determining a score for each smart device of the plurality of smart devices; communicating the score between each smart device of the plurality of smart devices; comparing the score between each smart device of the plurality of smart devices; and executing the command at one smart device of the plurality of smart devices based on comparing the score between each smart device.

Abstract: Total knee replacements for hinged knee implants include a tibial member, a femoral member, a hinge assembly having a laterally extending axle configured to hingedly attach the femoral member to the tibial member, and a lock mechanism in communication with the hinge assembly. The lock mechanism is configured to (i) lock the femoral member in alignment with the tibial member for a full extension or other defined stabile walking configuration to thereby allow an arthrodesis or stiff knee gait and (ii) unlock to allow the femoral and tibial members to pivot relative to each other for flexion or bending when not ambulating.

Abstract: In a hierarchical multiple-node supply chain, a commodity is sold a first time at a first end of the supply chain and is resold multiple times across the supply chain before being sold a final time at a second end of the supply chain opposite the first end. A user who is a buyer and/or a seller within the supply chain is interacted with by exchanging text messages with a mobile phone device of the user to provide the user with a current price of the commodity for a type of the user within the supply chain, and to receive from the user an actual price of the commodity in a current transaction in which the user was involved. The type of the user includes a node within the supply chain to which the user corresponds.

Abstract: Total knee replacements for hinged knee implants include a tibial member, a femoral member, a hinge assembly having a laterally extending axle configured to hingedly attach the femoral member to the tibial member, and a lock mechanism in communication with the hinge assembly. The lock mechanism is configured to (i) lock the femoral member in alignment with the tibial member for a full extension or other defined stabile walking configuration to thereby allow an arthrodesis or stiff knee gait and (ii) unlock to allow the femoral and tibial members to pivot relative to each other for flexion or bending when not ambulating.

Abstract: An actuator system for a machine includes a linear hydraulic actuator connected to a dipper of the machine, and a hydraulic system fluidly connected to the actuator and configured to selectively direct fluid to the actuator. A component of the hydraulic system is mounted on the dipper. The system also includes an overcenter link coupled to a door of the dipper and biased to maintain the door in a closed position. A piston assembly of the actuator is configured to move the overcenter link in a first direction, via contact between the piston assembly and the overcenter link, thereby transitioning the door from the closed position to an open position.

Abstract: An actuator system for a machine includes a hydraulic actuator connected to a dipper of the machine, and a hydraulic system fluidly connected to the actuator and configured to selectively direct fluid to the actuator. A component of the hydraulic system is mounted on the dipper. The system also includes an overcenter link coupled to a door of the dipper and biased to maintain the door in a closed position. The actuator is operable to move the overcenter link in a first direction, thereby transitioning the door from the closed position to an open position.

Abstract: A hydraulic system for a power shovel may have a cylinder operatively connectable to a dipper door of the power shovel, a reservoir located at and fluidly connected to the cylinder, and an accumulator located at and fluidly connected to the cylinder in parallel with the reservoir. The hydraulic system may further have a control valve disposed between the cylinder, the reservoir, and the accumulator. The control valve may be movable to selectively direct fluid from the cylinder into the accumulator and fluid from the reservoir into the cylinder.