Patents by Inventor Frank RUTSCH

Frank RUTSCH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING ALLOGRAFT VASCULOPATHY, MOYAMOYA DISEASE, MOYAMOYA SYNDROME AND INTIMAL PROLIFERATION
    Publication number: 20240016951
    Abstract: The present disclosure provides compositions and methods for treating allograft vasculopathy, for treating Moyamoya Diseases (MMD) and Moyamoya Syndrome (MMS), for treating inhibiting or preventing unwanted intimal proliferation in a subject by administering an ectonucleotide pyrophosphatase phosphodiesterase-1 (ENPP1) agent or an ectonucleotide pyrophosphatase phosphodiesterase-3 (ENPP3).
    Type: Application
    Filed: December 30, 2022
    Publication date: January 18, 2024
    Inventors: Damon Banks, Catherine A. Nester, Edward Skolnik, Markus Walz, Frank Rutsch, Yvonne Nitschke
  • COMPOSITIONS AND METHODS FOR TREATING PERIPHERAL ARTERY DISEASE
    Publication number: 20230372455
    Abstract: The present disclosure provides compositions and methods for treating Peripheral Artery Diseases in a subject by administering an ectonucleotide pyrophosphatase phosphodiesterase-1 (ENPP1) agent or an ectonucleotide pyrophosphatase phosphodiesterase-3 (ENPP3).
    Type: Application
    Filed: November 23, 2022
    Publication date: November 23, 2023
    Inventors: David Thompson, Frank Rutsch, Yvonne Nitschke
  • COMPOSITIONS AND METHODS FOR INHIBITING VASCULAR SMOOTH MUSCLE CELL PROLIFERATION
    Publication number: 20230330307
    Abstract: The present disclosure provides compositions and methods for treating vascular smooth muscle cell proliferation in a subject that does not have a deficiency of ectonucleotide pyrophosphatase phosphodiesterase-1 (ENPP1) resulting in a pathological disease of calcification or ossification by administering an ENPP1 agent or an ENPP3 agent.
    Type: Application
    Filed: November 23, 2022
    Publication date: October 19, 2023
    Inventors: Frank Rutsch, David Thompson, Yvonne Nitschke, Robert Terkeltaub
  • METHODS OF TREATING MYOINTIMAL PROLIFERATION
    Publication number: 20220354933
    Abstract: The present invention provides a method of treating myointimal proliferation by administering a recombinant human soluble ectonucleotide pyrophosphatase phosphodiesterase (hsNPP1), active fragment or fusion protein thereof.
    Type: Application
    Filed: May 18, 2022
    Publication date: November 10, 2022
    Inventors: Yan YAN, Anumeha SHAH, Ashmita SAIGAL, Herman GRIFFIN, Susan Faas MCKNIGHT, Andre MAROZSAN, Kim ASKEW, Yvonne NITSCHKE, Frank RUTSCH
  • Methods of treating myointimal proliferation
    Patent number: 11364284
    Abstract: The present invention provides a method of treating myointimal proliferation by administering a recombinant human soluble ectonucleotide pyrophosphatase phosphodiesterase (hsNPP1), active fragment or fusion protein thereof.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: June 21, 2022
    Assignees: Inozyme Pharma, Inc., Westfaelische Wilhelms-Universitaet Muenster
    Inventors: Yan Yan, Anumeha Shah, Ashmita Saigal, Herman Griffin, Susan Faas McKnight, Andre Marozsan, Kim Askew, Yvonne Nitschke, Frank Rutsch
  • METHODS OF TREATING MYOINTIMAL PROLIFERATION
    Publication number: 20200306349
    Abstract: The present invention provides a method of treating myointimal proliferation by administering a recombinant human soluble ectonucleotide pyrophosphatase phosphodiesterase (hsNPP1), active fragment or fusion protein thereof.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 1, 2020
    Inventors: Yan YAN, Anumeha SHAH, Ashmita SAIGAL, Herman GRIFFIN, Susan Faas MCKNIGHT, Andre MAROZSAN, Kim ASKEW, Yvonne NITSCHKE, Frank RUTSCH