Abstract: Provided are methods for increasing the amount or activity of FMR1 RNA, and in certain instances of increasing the amount of FMRP protein, in an animal. Such methods are useful to prevent or ameliorate at least one symptom of a Fragile X-Spectrum disorder. Such Fragile X-Spectrum disorders include FXS, FXTAS, and FXPOI.

Abstract: Methods, systems, and devices for the visualization of the region of a 3-dimensional space obstructed from a viewing location by an ellipsoid are disclosed. In an embodiment, the obstructed region may be defined from primitive elements which are combined using Boolean operations. The primitive elements chosen may be represented using both implicit functions and/or parametric surfaces. In an embodiment, the implicit function representation may be used to quickly determine points on candidate surfaces which may be obstructed from view. In an embodiment, the parametric representation may be used to provide ray-surface intersection solutions enabling visualization of the boundary surface of the obstruction region.

Abstract: Methods, systems, and devices for the visualization of the region of a 3-dimensional space obstructed from a viewing location by an ellipsoid are disclosed. In an embodiment, the obstructed region may be defined from primitive elements which are combined using Boolean operations. The primitive elements chosen may be represented using both implicit functions and/or parametric surfaces. In an embodiment, the implicit function representation may be used to quickly determine points on candidate surfaces which may be obstructed from view. In an embodiment, the parametric representation may be used to provide ray-surface intersection solutions enabling visualization of the boundary surface of the obstruction region.

Abstract: A casting is made from a low melting point alloy having a solidus temperature in the range of 35.degree.-300.degree. C. by subjecting a charge of molten alloy to pre-pressurization then delivering the charge at a flow rate of 0.1 to 1 kg/sec into a die and maintaining the metal in the die under pressure for a time in excess of that required to fill the die.

Abstract: A ruthenium catalyst of improved performance for the dimerisation and hydrodimerisation of olefinically unsaturated compounds, especially acrylonitrile, is obtained by co-precipitating a ruthenium compound with an aluminium oxide and/or hydroxide.