Patents by Inventor Franklin P. Bymaster

Franklin P. Bymaster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for providing neuro-protective effects
    Publication number: 20030022889
    Abstract: The present invention provides a method for treating ALS and for providing a neuro-protective effect comprising administering a therapeutically effective of olanzapinc or a pharmaceutically acceptable salt or solvate thereof.
    Type: Application
    Filed: August 27, 2002
    Publication date: January 30, 2003
    Inventors: Franklin P. Bymaster, Gary D. Tollefson
  • Combination therapy for treatment of psychoses
    Patent number: 6147072
    Abstract: The invention relates to a method of treating psychosis, acute mania, mild anxiety states or depression in combination with psychotic episodes by administering to a patient a combination of an atypical antipsychotic and a serotonin reuptake inhibitor.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: November 14, 2000
    Assignee: Eli Lilly and Company
    Inventors: Franklin P. Bymaster, Kenneth W. Perry, Gary D. Tollefson
  • Method for treating bipolar disorder
    Patent number: 6117890
    Abstract: The present invention provides a method for treating or alleviating the symptoms of bipolar disorder, comprising administering an effective amount of xanomeline (3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine) .
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: September 12, 2000
    Assignee: Eli Lilly and Company
    Inventors: Franklin P Bymaster, Harlan E Shannon
  • Method for treating excessive aggression
    Patent number: 6090829
    Abstract: The present invention provides a method of treating conduct disorder in a human using a compound of formula (I) ##STR1##
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: July 18, 2000
    Assignee: Eli Lilly and Company
    Inventors: Neil C Bodick, Franklin P Bymaster, Harlan E Shannon
  • Method for treating disruptive behavior disorders with xanomeline
    Patent number: 6043258
    Abstract: This invention relates to the use of xanomeline for the treatment of Disruptive Behavior Disorder and Attention Deficit Hyperactivity Disorder.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: March 28, 2000
    Assignee: Eli Lilly and Company
    Inventors: Franklin P Bymaster, Harlan E Shannon
  • Method for treating mental retardation
    Patent number: 6034108
    Abstract: The present invention is directed to a method for using 3-(4-hexyloxy-1,2,5-thiadiazol-3yl)-1,2,5,6-tetrahydro-1-methylpyridine, i.e., xanomeline, for the treatment of autism and mental retardation.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: March 7, 2000
    Assignee: Eli Lilly and Company
    Inventors: Franklin P Bymaster, Harlan E Shannon
  • Method for treating anxiety with muscarinic cholinergic receptor agonists
    Patent number: 5888999
    Abstract: The present invention relates a method for treating anxiety using azacyclic and azabicyclic pyrazine compounds.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: March 30, 1999
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5852036
    Abstract: The present invention provides a method for treating anxiety in humans using compounds which modulate a muscarinic receptor.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: December 22, 1998
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5852037
    Abstract: The present invention provides a method for treating anxiety in humans using azacyclic or azabicyclic compounds.
    Type: Grant
    Filed: October 22, 1996
    Date of Patent: December 22, 1998
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5763457
    Abstract: The present invention relates a method for treating anxiety using azacyclic and azabicyclic oxadiazole compounds.
    Type: Grant
    Filed: October 22, 1996
    Date of Patent: June 9, 1998
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5726193
    Abstract: The present invention provides a method for treating anxiety in humans using heterocyclic compounds.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: March 10, 1998
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5708014
    Abstract: The present invention provides a method for treating anxiety in humans using of Formula I herein disclosed compounds.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: January 13, 1998
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Transdermal formulation
    Patent number: 5605701
    Abstract: The present invention provides a method for treating a condition associated with muscarinic receptor modulation using a 3-[4-(butylthio)-1,2,5-thiadiazol-3-yl]-1-azabicyclo-[2.2.2]octane transdermal formulation. The invention provides desired transdermal 3-[3-(hexylthio)-1,2,5-thiadiazol-4-yl]-1,2,5,6-tetrahydro-1-methylpyridin e patch formulations.
    Type: Grant
    Filed: February 17, 1995
    Date of Patent: February 25, 1997
    Assignee: Eli Lilly and Company
    Inventors: Franklin P. Bymaster, Harlan E. Shannon, Lisa A. Shipley, Kirti H. Valia
  • Method for treating anxiety
    Patent number: 5574029
    Abstract: The present invention provides a method for treating anxiety in a human in need thereof, comprising administering an antianxiety amount of a muscarinic agonist compound of the general formula ##STR1## wherein X R.sup.43, R.sup.44, R.sup.45 and R.sup.46 are defined in the disclosure.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: November 12, 1996
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5574053
    Abstract: The present invention provides a method for treating anxiety in humans using a compound of the formula ##STR1## as described in the specification which modulates a muscarinic receptor.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: November 12, 1996
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5574028
    Abstract: The present invention provides a method for treating anxiety in a human in need thereof, comprising administering to the human an antianxiety amount of a muscarinic agonist compound of the general formula ##STR1## wherein Z is a 5-membered heterocyclic ring as defined in the disclosure.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: November 12, 1996
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5488056
    Abstract: The present invention provides a method for treating anxiety in humans using heterocyclic compounds.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: January 30, 1996
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon
  • Method for treating anxiety
    Patent number: 5484794
    Abstract: The present invention provides a method for treating anxiety in humans using heterocyclic compounds.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: January 16, 1996
    Assignee: Eli Lilly and Company
    Inventors: Neil C. Bodick, Franklin P. Bymaster, Walter W. Offen, Harlan E. Shannon