Abstract: The disclosure relates to a microfluidic analysis device and to a method for operating the microfluidic analysis device. The method comprises the following steps: providing a sample containing DNA, performing a PCR pre-amplification of the sample, dividing the sample into at least two reaction compartments, and performing at least one singleplex detection in each of the at least two reaction compartments. The singleplex detection is performed in each case by means of an isothermal amplification system.

Abstract: A mold sensor is configured with an enclosed chamber in which a nutrient-treated substrate is positioned. The mold sensor includes an optical sensor that is configured to measure optical properties in the enclosed chamber. A controller operates the optical sensor and is programmed to detect a presence of mold growing in the chamber based on the optical properties measured by the optical sensor.

Abstract: The present disclosure relates to a method for treating a biological sample contained in a transport medium. At least one complexing agent is added to the transport medium, which complexing agent forms complexes with alkaline-earth metal ions. In the method, a device can be used which comprises, in succession, a porous volume filter and a membrane filter having a pore size in the range of 0.2 ?m to 2.0 ?m.

Abstract: A mold sensor include a housing that defines an enclosed chamber in which a nutrient-treated substrate is positioned. The mold sensor includes a substrate advancement mechanism that is configured to selectively move the substrate to expose a surface of the substrate within the chamber. The mold sensor includes a sensor configured to detect mold growth on the substrate within the chamber.

Abstract: A method for producing a carrier element for receiving a sample liquid is disclosed. The method includes a step of coating a carrier substrate with a light-sensitive polymer layer in order to obtain a coated carrier substrate, in particular wherein the carrier substrate has a hydrophilic surface quality. The method also includes an exposure and development step wherein the coated carrier substrate is exposed and developed in order to obtain a structured polymer layer. The method also includes a fluorination step, wherein the structured polymer layer on the carrier substrate is fluorinated in order to produce the carrier element for receiving the sample liquid, in particular wherein the structured polymer layer obtains a hydrophobic surface quality as a result of the fluorination step.

Abstract: A mold sensor is configured with an enclosed chamber in which a nutrient-treated substrate is positioned. The mold sensor includes a sensing system that is configured to measure a property of the substrate that corresponds to a pH value of the substrate. A controller operates the sensing system and is programmed to detect a presence of mold growing in the chamber by estimating the pH value from the measured property.

Abstract: A system for detecting mold includes a housing defining a chamber and an opening through a surface. The system includes a movable grate for selectively covering the opening. The system includes a substrate treated to promote mold growth. The system includes a mechanism for moving the substrate to move previously unexposed portions into the chamber. The system includes a thermal control system to maintain predetermined environmental conditions in the chamber. The system includes a sensor configured to detect mold growth in the chamber. The system includes a mold suppressor to kill mold in the chamber when activated. The system includes a controller to coordinate operation of the components to detect mold growth in an environment.

Abstract: In an amplification reaction in a microfluidic apparatus, the reaction is carried out using starting substances tagged with fluorophore and quencher. The detection of reaction products occurs according to the disclosure by a separation of fluorophore and quencher occurring in the context of the amplification reaction. For the detection reaction, at least one energy-transferring substance is added and the evaluation occurs on the basis of the fluorescence emission of the fluorophores which occurs.

Abstract: In a method for creating hydrophilic surfaces or surface regions on one or more silicon surfaces of a substrate, a vapour phase of hydrogen peroxide is generated in a reactor by heating an aqueous hydrogen peroxide solution. The substrate having the silicon surface or surfaces to be treated is exposed to the vapour phase, whereby a hydrophilisation of the silicon surfaces in achieved.

Abstract: A mold sensor is configured with an enclosed chamber in which a nutrient-treated substrate is positioned. The mold sensor includes a sensor for measuring electrical properties of the substrate. The substrate includes conductive elements to interface with a controller to measure the electrical properties. The controller operates the sensor and is programmed to detect a presence of mold growing in the chamber based on the electrical properties.

Abstract: A mold sensor is configured with an enclosed chamber in which a nutrient-treated substrate is positioned. The mold sensor includes a sensing system that is configured to measure properties of pressure waves within the enclosed chamber. A controller operates the sensing system and is programmed to detect a presence of mold growing in the chamber based on the characteristics of the pressure wave response within the chamber.

Abstract: A centrifuge unit for a microfluidic device for processing liquid samples includes a centrifuge cup and at least one centripetal force-dependent valve function.

Abstract: A microfluidic device is for processing and aliquoting a sample liquid. The microfluidic device has a dividing chamber for receiving a starting volume of the sample liquid. The dividing chamber has a plurality of cavities for receiving sub-volumes of the sample liquid, the sub-volumes being usable for analytical reactions. The microfluidic device also has a microfluidic network for using the dividing chamber in a fluid-mechanical manner and at least one pump device for pumping fluids within the device. The at least one pump device and the microfluidic network are configured to pump the sample liquid, as a first phase, and a sealing liquid, as a second phase, through the microfluidic network and into the dividing chamber in order to seal the sub-volumes of the sample liquid in the cavities using the sealing liquid.

Abstract: The disclosure relates to a method and a device for obtaining a breath sample of a test person, wherein the test person inhales a droplet mist which is preferably colder than the ambient temperature. The material exhaled and/or ejected by the test person is collected as a breath sample in one or more collection vessels.

Abstract: A device to electrochemically sequence DNA that includes a redox species includes at least one edge electrode, at least one stack of insulator material, and a pair of DNA translocation electrodes including a DNA translocation working electrode and a DNA translocation counter electrode, where the thickness of the at least one edge electrode is about 0.5 nanometers, and the thickness of the at least one stack of insulator material is about 10 nanometers. Methods of electrochemically sequencing a strand of DNA are also provided.

Abstract: The disclosure relates to a process for producing a base of an analysis cell for analyzing a biochemical material. Here, carbon-rich precursor molecules and low-carbon precursor molecules are deposited on a substrate in a defined mixing ratio in order to form a precursor layer, wherein the low-carbon precursor molecules have a defined size and a hydrophobic end group. In a further step, the precursor layer is post-treated in a suitable manner in order to produce the base as a layer with at least one pore having a pore size dependent on the defined size and a pore count dependent on the defined mixing ratio.

Abstract: The disclosure relates to a method for producing a sequencing unit for sequencing a biochemical material. In this case, at least one sequencing pore for sequencing the biochemical material in a precursor layer is created in a thermal lithography process in order to produce a pre-structured layer. The pre-structured layer is then converted into a graphene layer by heating to a conversion temperature in order to produce the sequencing unit. The sequencing pore is reduced to a size suitable for sequencing, depending on the transformation temperature.

Abstract: A blood pressure and cardiac monitoring system includes a sensing assembly, a processor, a memory, a communication interface, and any suitable computer implemented modules communicatively coupled to each other via a bus. The sensing assembly comprises of a first sensor (single or multi-axes) located at a first axis of a target generating a first time-dependent motion waveform representative of one or more contractile properties of the target's heart and a second sensor (single or multi-axes) located at a second axis of the target generating a second time dependent motion waveform representative of the target's blood flow. The first and second sensor can be integrated in a multi-axes sensor which sense both the axes. The processor is configured to receive the first time dependent motion waveform and the second time dependent motion waveform, and to determine a first time difference between a vital sign present in the first time dependent motion waveform and the second time dependent motion waveform.

Abstract: A microfluidic device includes an array unit and a nanostructure connected to the array unit, wherein the array unit comprises array cells with substances for a polymerase chain reaction. The array cells include nucleotides with stop properties according to the Sanger sequencing method and primers for an asymmetric polymerase chain reaction. The nanostructure is configured to determine lengths of nucleotide strands formed by the polymerase chain reaction.

Abstract: A device for preparing sample material is designed as a rotary device by means of which a defined quantity of liquid can be drawn in into a sample receiving chamber for the sample material or can be expelled from the sample receiving chamber for the sample material, by means of a rotary motion.