Patents by Inventor Frauke Hildegard Elisabeth Alves

Frauke Hildegard Elisabeth Alves has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MCK-10 a novel receptor tyrosine kinase
    Patent number: 6897029
    Abstract: The present invention relates to the novel family of receptor tyrosine kinases, herein referred to as MCK-10, to nucleotide sequences and expression vectors encoding MCK-10, and to methods of inhibiting MCK-10 activity. The invention relates to differentially spliced isoforms of MCK-10 and to other members of the MCK-10 receptor tyrosine kinase family. Genetically engineered host cells that express MCK-10 may be used to evaluate and screen drugs involved in MCK-10 activation and regulation. The invention relates to the use of such drugs, in the treatment of disorders, including cancer, by modulating the activity of MCK-10.
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: May 24, 2005
    Assignee: Max Planck Gesellschaft zur Forderung der Wissenschaften
    Inventors: Axel Ullrich, Frauke Hildegard Elisabeth Alves
  • DNA encoding MCK-10, a novel receptor tyrosine kinase
    Patent number: 6051397
    Abstract: The present invention relates to the novel family of receptor tyrosine kinases, herein referred to as MCK-10, to nucleotide sequences and expression vectors encoding MCK-10, and to methods of inhibiting MCK-10 activity. The invention relates to differentially spliced isoforms of MCK-10 and to other members of the MCK-10 receptor tyrosine kinase family. Genetically engineered host cells that express MCK-10 may be used to evaluate and screen drugs involved in MCK-10 activation and regulation. The invention relates to the use of such drugs, in the treatment of disorders, including cancer, by modulating the activity of MCK-10.
    Type: Grant
    Filed: November 16, 1993
    Date of Patent: April 18, 2000
    Assignee: Max Planck Gesellschaft zur Forderung der Wissenschaften
    Inventors: Axel Ullrich, Frauke Hildegard Elisabeth Alves
  • Recombinant DNA encoding CCK 2, a receptor tyrosine kinase
    Patent number: 5677144
    Abstract: A recombinant nucleic acid molecule encoding a receptor tyrosine kinase identified herein as CCK-2, and specific functional fragments thereof are provided. Also, provided is a nucleic acid encoding a chimeric protein comprising all or a specific part of CCK-2, as well as a process of employing the disclosed nucleic acids to produce the proteins encoded thereby.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: October 14, 1997
    Inventors: Axel Ullrich, Frauke Hildegard Elisabeth Alves