Patents by Inventor Fred R. Kohn

Fred R. Kohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified antibody variable domains
    Patent number: 5766886
    Abstract: Methods are described for identifying the amino acid residues of an antibody variable domain which may be modified without diminishing the native affinity of the domain for antigen while reducing its immunogenicity with respect to a heterologous species and for preparing so modified antibody variable domains which are useful for administration to heterologous species. Antibody variable regions prepared by the methods of the invention are also described.
    Type: Grant
    Filed: August 13, 1993
    Date of Patent: June 16, 1998
    Assignee: Xoma Corporation
    Inventors: Gary M. Studnicka, Roger G. Little, II, Dianne M. Fishwild, Fred R. Kohn