Patents by Inventor Fred Rothstein

Fred Rothstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
    Patent number: 7125552
    Abstract: The method for immune serum globulin purification relates to the purification of immune globulins from blood plasma with a high degree of efficiency and a high rate of recovery. The immune globulin source is Cohn's fraction I+II+III or II+III prepared from plasma or plasma intermediates by precipitation of the paste at pH 6.7 to 6.8 in the presence of 20% ethanol and 80% purified water. A glycine extraction is followed by an anion exchange chromatography column step to achieve a significantly high yield and high purity of the concentrated protein.
    Type: Grant
    Filed: May 13, 2005
    Date of Patent: October 24, 2006
    Assignee: Hemacare Corporation
    Inventors: Joshua Levy, Fred Rothstein, Bahman Shimiaei
  • Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
    Publication number: 20050209442
    Abstract: The method for immune serum globulin purification relates to the purification of immune globulins from blood plasma with a high degree of efficiency and a high rate of recovery. The immune globulin source is Cohn's fraction I+II+III or II+III prepared from plasma or plasma intermediates by precipitation of the paste at pH 6.7 to 6.8 in the presence of 20% ethanol and 80% purified water. A glycine extraction is followed by an anion exchange chromatography column step to achieve a significantly high yield and high purity of the concentrated protein.
    Type: Application
    Filed: May 13, 2005
    Publication date: September 22, 2005
    Inventors: Joshua Levy, Fred Rothstein, Bahman Shimiaei
  • Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
    Patent number: 6893639
    Abstract: The method for immune serum globulin purification relates to the purification of immune globulins from blood plasma with a high degree of efficiency and a high rate of recovery. The immune globulin source is Cohn's fraction I+II+III or II+III prepared from plasma or plasma intermediates by precipitation of the paste at pH 5.7 to 5.8 in the presence of 20% ethanol and 80% purified water. A glycine extraction is followed by an anion exchange chromatography column step to achieve a significantly high yield and high purity of the concentrated protein.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: May 17, 2005
    Assignee: Hemacare Corporation
    Inventors: Joshua Levy, Fred Rothstein, Bahman Shimiaei
  • Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
    Publication number: 20050080238
    Abstract: The method for immune serum globulin purification relates to the purification of immune globulins from blood plasma with a high degree of efficiency and a high rate of recovery. The immune globulin source is Cohn's fraction I+II+III or II+III prepared from plasma or plasma intermediates by precipitation of the paste at pH 5.7 to 5.8 in the presence of 20% ethanol and 80% purified water. A glycine extraction is followed by an anion exchange chromatography column step to achieve a significantly high yield and high purity of the concentrated protein.
    Type: Application
    Filed: October 4, 2004
    Publication date: April 14, 2005
    Inventors: Joshua Levy, Fred Rothstein, Bahman Shimiaei
  • Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
    Publication number: 20030078384
    Abstract: The method for immune serum globulin purification relates to the purification of immune globulins from blood plasma with a high degree of efficiency and a high rate of recovery. The immune globulin source is Cohn's fraction I+II+III or II+III prepared from plasma or plasma intermediates by precipitation of the paste at pH 6.7 to 6.8 in the presence of 20% ethanol and 80% purified water. A glycine extraction is followed by an anion exchange chromatography column step to achieve a significantly high yield and high purity of the concentrated protein.
    Type: Application
    Filed: October 19, 2001
    Publication date: April 24, 2003
    Inventors: Joshua Levy, Fred Rothstein, Bahman Shimiaei
  • Method for isolating biomolecules from a biological sample with linear polymers
    Patent number: 5599719
    Abstract: A method, composition, and kit for isolating biomolecules from a biological sample wherein the sample is mixed with a soluble, linear polymer, such as polyvinylpyrrolidone, to form a precipitate. The biomolecule of interest is found in the precipitate or is isolated from the supernatant.
    Type: Grant
    Filed: August 26, 1993
    Date of Patent: February 4, 1997
    Assignee: Middlesex Sciences, Inc.
    Inventors: James E. Woiszwillo, Fred Rothstein