Abstract: Systems and methods of are disclosed for providing visual feedback to a subject during magnetic resonance imaging, where the visual feedback is associated with input provided by the subject to a magnetic resonance compatible touch panel. A video camera is employed to record video images of the interaction between the subject and the touch panel, and the video images are processed to generate a real-time video signal including a rendering of the input provided to the touch panel and the interaction between the subject's hands and the touch panel. The real-time video signal is provided to the subject as visual feedback, and is displayed within a time duration that is sufficiently fast to avoid the detection of the visual feedback as an error signal with the subject's brain in relation to the sense of proprioception. A measurement of the force applied to the touch panel by the subject may be recorded and employed when rendering the real-time video.

Abstract: Systems and methods are provided for performing an intraoperative assessment of brain function based on input that is obtained using a touch panel device, in response to a task, and in the presence of an intervention that is applied to a selected region of the brain. The intervention may be stimulation of the selected region of the brain, such as direct cortical stimulation. In some embodiments, a measure is determined based on the input received from the touch panel. The measure may be a performance measure, related to the performance of the task, and/or a functional measure, associated with an inferred function of the selected region of the brain. In some embodiments, an image of the brain that is registered to an intraoperative reference frame may be annotated or otherwise modified within the selected region based on the measure.

Abstract: Systems and methods are provided for performing an intraoperative assessment of brain function based on input that is obtained using a touch panel device, in response to a task, and in the presence of an intervention that is applied to a selected region of the brain. The intervention may be stimulation of the selected region of the brain, such as direct cortical stimulation. In some embodiments, a measure is determined based on the input received from the touch panel. The measure may be a performance measure, related to the performance of the task, and/or a functional measure, associated with an inferred function of the selected region of the brain. In some embodiments, an image of the brain that is registered to an intraoperative reference frame may be annotated or otherwise modified within the selected region based on the measure.

Abstract: Systems and methods of are disclosed for providing visual feedback to a subject during magnetic resonance imaging, where the visual feedback is associated with input provided by the subject to a magnetic resonance compatible touch panel. A video camera is employed to record video images of the interaction between the subject and the touch panel, and the video images are processed to generate a real-time video signal including a rendering of the input provided to the touch panel and the interaction between the subject's hands and the touch panel. The real-time video signal is provided to the subject as visual feedback, and is displayed within a time duration that is sufficiently fast to avoid the detection of the visual feedback as an error signal with the subject's brain in relation to the sense of proprioception. A measurement of the force applied to the touch panel by the subject may be recorded and employed when rendering the real-time video.

Abstract: The present invention provides a method and device to record and visualize drawing and writing movements during functional magnetic resonance imaging (fMRI) of brain activity. The system includes a touch-sensitive tablet, an elevated mounting platform, a stylus, and a controller box, as well as the necessary cabling and software. All equipment residing inside the magnet room is non-ferromagnetic and does not interfere with scanner operation and does not affect fMRI data quality. Individuals lying inside the scanner interact with device in a natural, intuitive way, similar to writing with pen and paper. Drawing motions captured by the tablet are displayed through a pair of fMRI-compatible goggles or by using a projector and screen. Other visual stimuli can be concurrently presented with the drawing motions for the purpose of assessing specific aspects of human behavior. The system allows for a plurality of experiments to be performed, all while brain activity is measured and recorded.

Abstract: An optical image-based tracking system determines the position and orientation of objects such as biological materials or medical devices within or on the surface of a human body undergoing Magnetic Resonance Imaging (MRI). Three-dimensional coordinates of the object to be tracked are obtained initially using a plurality of MR-compatible cameras. A calibration procedure converts the motion information obtained with the optical tracking system coordinates into coordinates of an MR system. A motion information file is acquired for each MRI scan, and each file is then converted into coordinates of the MRI system using a registration transformation. Each converted motion information file can be used to realign, correct, or otherwise augment its corresponding single MR image or a time series of such MR images.