Patents by Inventor Frederic A. Fellouse
Frederic A. Fellouse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220235123Abstract: The invention provides novel synthetic antibodies directed against VEGF and uses thereof.Type: ApplicationFiled: November 18, 2021Publication date: July 28, 2022Inventors: FREDERIC FELLOUSE, JASON MOFFAT, SACHDEV SIDHU, CHANIYILPARAMPI NANAPPAN RAMCHAND, RAVIKANT HARIT, REENA ARORA, AJU ANTONY, SANTHI VINODH
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Patent number: 11254738Abstract: The invention provides novel synthetic antibodies directed against VEGF and uses thereof.Type: GrantFiled: September 7, 2017Date of Patent: February 22, 2022Assignees: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO BANTING INSTITUTE, SAKSIN LIFESCIENCES PVT. LTD.Inventors: Frederic Fellouse, Jason Moffat, Sachdev Sidhu, Cn Ramchand, Ravikant Harit, Reena Arora, Aju Antony, Santhi Vinodh
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Publication number: 20190202904Abstract: The invention provides novel synthetic antibodies directed against VEGF and uses thereof.Type: ApplicationFiled: September 7, 2017Publication date: July 4, 2019Applicant: University of TorontoInventors: Frederic FELLOUSE, Jason MOFFAT, Sachdev SIDHU, CN RAMCHAND, Ravikant HARIT, Reena ARORA, Aji ANTONY, Santhi VINODH
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Publication number: 20170073405Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: ApplicationFiled: April 25, 2016Publication date: March 16, 2017Inventors: Germaine FUH, Hans-Peter GERBER, Wei-Ching LIANG, Frederic FELLOUSE, Sachdev S. SIDHU, Christian WIESMANN
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Patent number: 9353177Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: GrantFiled: March 3, 2015Date of Patent: May 31, 2016Assignee: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Publication number: 20150232549Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: ApplicationFiled: March 3, 2015Publication date: August 20, 2015Inventors: Germaine FUH, Hans-Peter GERBER, Wei-Ching LIANG, Frederic FELLOUSE, Sachdev S. SIDHU, Christian WIESMANN
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Publication number: 20150175689Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: ApplicationFiled: January 23, 2015Publication date: June 25, 2015Inventors: Germaine FUH, Hans-Peter GERBER, Wei-Ching LIANG, Frederic FELLOUSE, Sachdev S. SIDHU, Christian WIESMANN
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Patent number: 9018357Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: GrantFiled: June 25, 2013Date of Patent: April 28, 2015Assignee: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Patent number: 8975381Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: GrantFiled: June 27, 2013Date of Patent: March 10, 2015Assignee: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Patent number: 8957187Abstract: The invention provides antibodies or antigen binding fragments thereof to DR5 and HER-2. The antibodies and/or antigen binding fragments thereof comprise variant CDRs comprising highly restricted amino acid sequence diversity. The invention also provides these polypeptides as fusion polypeptides to heterologous polypeptides such as at least a portion of phage or viral coat proteins, tags and linkers. In addition, compositions and methods of use for treatment of cancer and immune related conditions are provided.Type: GrantFiled: December 1, 2006Date of Patent: February 17, 2015Assignee: Genentech, Inc.Inventors: Sachdev S. Sidhu, Sara C. Birtalan, Frederic A. Fellouse
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Publication number: 20130315918Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: ApplicationFiled: June 27, 2013Publication date: November 28, 2013Applicant: Genentech, Inc.Inventors: GERMAINE FUH, HANS-PETER GERBER, WEI-CHING LIANG, FREDERIC FELLOUSE, SACHDEV S. SIDHU, CHRISTIAN WIESMANN
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Publication number: 20130266581Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: ApplicationFiled: June 25, 2013Publication date: October 10, 2013Inventors: Germaine FUH, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Patent number: 8512699Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: GrantFiled: June 15, 2010Date of Patent: August 20, 2013Assignee: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Patent number: 8492527Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: GrantFiled: December 22, 2011Date of Patent: July 23, 2013Assignee: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Publication number: 20120322982Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: ApplicationFiled: December 22, 2011Publication date: December 20, 2012Applicant: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Patent number: 8101177Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naive libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: GrantFiled: July 27, 2010Date of Patent: January 24, 2012Assignee: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Patent number: 8092797Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: GrantFiled: February 4, 2010Date of Patent: January 10, 2012Assignee: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Publication number: 20110020346Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: ApplicationFiled: July 27, 2010Publication date: January 27, 2011Applicant: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Publication number: 20110014198Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: ApplicationFiled: June 15, 2010Publication date: January 20, 2011Applicant: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann
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Patent number: 7811785Abstract: Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.Type: GrantFiled: January 27, 2006Date of Patent: October 12, 2010Assignee: Genentech, Inc.Inventors: Germaine Fuh, Hans-Peter Gerber, Wei-Ching Liang, Frederic A. Fellouse, Sachdev S. Sidhu, Christian Wiesmann