Patents by Inventor Frederic Louis Lizzi
Frederic Louis Lizzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8152723Abstract: An ultrasound system is provided which includes a therapy ultrasound transducer and a diagnostic ultrasound transducer and operates in accordance with a method to direct the application of the therapy ultrasound. The method includes operating the diagnostic ultrasound transducer to acquire a first ultrasound image; simultaneously operating the diagnostic ultrasound transducer and therapy ultrasound transducer for a second interval to acquire a second ultrasound image; and determining a difference in the first and second images indicative of the pattern of the therapy ultrasound transducer signal. The difference in the images, which result from enhanced non-linearities and propagation distortions induced by the high intensity therapy ultrasound, can be obtained by subtracting the two images.Type: GrantFiled: July 22, 2009Date of Patent: April 10, 2012Assignee: Riverside Research InstituteInventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng
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Publication number: 20090287082Abstract: An ultrasound system is provided which includes a therapy ultrasound transducer and a diagnostic ultrasound transducer and operates in accordance with a method to direct the application of the therapy ultrasound. The method includes operating the diagnostic ultrasound transducer to acquire a first ultrasound image; simultaneously operating the diagnostic ultrasound transducer and therapy ultrasound transducer for a second interval to acquire a second ultrasound image; and determining a difference in the first and second images indicative of the pattern of the therapy ultrasound transducer signal. The difference in the images, which result from enhanced non-linearities and propagation distortions induced by the high intensity therapy ultrasound, can be obtained by subtracting the two images.Type: ApplicationFiled: July 22, 2009Publication date: November 19, 2009Inventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng
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Patent number: 7217242Abstract: Methods are provided for enhancing the image of brachytherapy seeds implanted in tissue using a transrectal ultrasound apparatus. In a first arrangement the resonance of the seeds is determined and the seeds are insonified using acoustic signals having a resonance frequency of the seeds to cause the seeds to vibrate. The vibrating seeds have enhanced detection using a Doppler ultrasound device. In a second arrangement the acoustic signature of the seeds is determined and used to enhance the imaging of the seeds using a correlation function. In a third arrangement images are taken of the tissue and implanted seeds prior to and during the application of mechanical stress to the tissue. A correlation between the unstressed and stressed tissue can cause enhanced imaging of the seeds.Type: GrantFiled: March 12, 2003Date of Patent: May 15, 2007Assignee: Riverside Research InstituteInventors: Sheikh Kaisar Alam, Ernest Joseph Feleppa, Frederic Louis Lizzi
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Publication number: 20040158152Abstract: An ultrasound system is provided which includes a therapy ultrasound transducer and a diagnostic ultrasound transducer and operates in accordance with a method to direct the application of the therapy ultrasound. The method includes operating the diagnostic ultrasound transducer to acquire a first ultrasound image; simultaneously operating the diagnostic ultrasound transducer and therapy ultrasound transducer for a second interval to acquire a second ultrasound image; and determining a difference in the first and second images indicative of the pattern of the therapy ultrasound transducer signal. The difference in the images, which result from enhanced non-linearities and propagation distortions induced by the high intensity therapy ultrasound, can be obtained by subtracting the two images.Type: ApplicationFiled: February 5, 2004Publication date: August 12, 2004Inventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng
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Patent number: 6726627Abstract: An ultrasound system is provided which includes a therapy ultrasound transducer and a diagnostic ultrasound transducer and operates in accordance with a method to direct the application of the therapy ultrasound. The method includes operating the diagnostic ultrasound transducer to acquire a first ultrasound image; simultaneously operating the diagnostic ultrasound transducer and therapy ultrasound transducer for a second interval to acquire a second ultrasound image; and determining a difference in the first and second images indicative of the pattern of the therapy ultrasound transducer signal. The difference in the images, which result from enhanced non-linearities and propagation distortions induced by the high intensity therapy ultrasound, can be obtained by subtracting the two images.Type: GrantFiled: January 24, 2003Date of Patent: April 27, 2004Assignee: Riverside Research InstituteInventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng
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Publication number: 20040039284Abstract: Methods are provided for enhancing the image of brachytherapy seeds implanted in tissue using a transrectal ultrasound apparatus. In a first arrangement the resonance of the seeds is determined and the seeds are insonified using acoustic signals having a resonance frequency of the seeds to cause the seeds to vibrate. The vibrating seeds have enhanced detection using a Doppler ultrasound device. In a second arrangement the acoustic signature of the seeds is determined and used to enhance the imaging of the seeds using a correlation function. In a third arrangement images are taken of the tissue and implanted seeds prior to and during the application of mechanical stress to the tissue. A correlation between the unstressed and stressed tissue can cause enhanced imaging of the seeds.Type: ApplicationFiled: March 12, 2003Publication date: February 26, 2004Applicant: Riverside Research InstituteInventors: Sheikh Kaisar Alam, Ernest Joseph Feleppa, Frederic Louis Lizzi
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Patent number: 6533726Abstract: An ultrasound system is provided which includes a therapy ultrasound transducer and a diagnostic ultrasound transducer and operates in accordance with a method to direct the application of the therapy ultrasound. The method includes operating the diagnostic ultrasound transducer to acquire a first ultrasound image; simultaneously operating the diagnostic ultrasound transducer and therapy ultrasound transducer for a second interval to acquire a second ultrasound image; and determining a difference in the first and second images indicative of the pattern of the therapy ultrasound transducer signal. The difference in the images, which result from enhanced non-linearities and propagation distortions induced by the high intensity therapy ultrasound, can be obtained by subtracting the two images.Type: GrantFiled: August 8, 2000Date of Patent: March 18, 2003Assignee: Riverside Research InstituteInventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng
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Patent number: 6423007Abstract: The concentration and/or radii of a contrast agent in a fluid can be estimated by acquiring ultrasound spectral data, performing spectral analysis to generate a linear estimation of the power spectrum, and correlating at least one spectral parameter to a predetermined distribution function for the contrast agent. If the mean radius squared of particles is known, then the concentration of contrast agent particles can be calculated. If the concentration is constant, then relative variations in mean radius squared can be determined.Type: GrantFiled: December 11, 2000Date of Patent: July 23, 2002Assignee: Riverside Research InstituteInventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng
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Patent number: 6312383Abstract: A dual-frequency band ultrasonic apparatus provides a first ultrasound signal to a region at a first frequency band and a second ultrasound signal at a second frequency band for monitoring the region. A processor controls the first and second ultrasound signals such that a predetermined phase relationship is achieved between the first frequency band signal and the second frequency band signal. The apparatus can employ a single transducer operable at both frequency bands or separate transducers for the first and second frequency bands.Type: GrantFiled: December 11, 2000Date of Patent: November 6, 2001Assignee: Riverside Research InstituteInventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng
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Patent number: 6238342Abstract: Clinical data, ultrasonic radio frequency (RF) backscatter spectral data and histological results of corresponding biopsy sites are stored in a database and are used to train a classifier suitable for real-time tissue classification and imaging. In clinical use, clinical data and ultrasonic RF backscatter data are applied as input variables to the trained classifier which assigns a likelihood of cancer (LOC) score to each pixel location in an ultrasound image. The LOC scores are then categorized by ranges, which can be established by user selected threshold values, to apply different colors or grey scale values distinguishing varying levels of suspicion (LOS) to each pixel position in real-time. This classification and display technique is especially valuable for guiding a person performing a needle biopsy of the prostate.Type: GrantFiled: May 26, 1999Date of Patent: May 29, 2001Assignee: Riverside Research InstituteInventors: Ernest Joseph Feleppa, Frederic Louis Lizzi, Tian Liu
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Publication number: 20010001108Abstract: The concentration and/or radii of a contrast agent in a fluid can be estimated by acquiring ultrasound spectral data, performing spectral analysis to generate a linear estimation of the power spectrum, and correlating at least one spectral parameter to a predetermined distribution function for the contrast agent. If the mean radius squared of particles is known, then the concentration of contrast agent particles can be calculated. If the concentration is constant, then relative variations in mean radius squared can be determined.Type: ApplicationFiled: December 11, 2000Publication date: May 10, 2001Applicant: Riverside Research InstituteInventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng
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Patent number: 6186951Abstract: Fluid flow rate and perfusion rate are measured using ultrasound techniques by introducing a contrast agent into a fluid stream and then selectively modifying the contrast agent particles within a target area by the application of a focused pulse of relatively low frequency ultrasonic energy, thus creating a zone of reduced backscatter in the target area. The restoration of the zone of reduced backscatter or the movement of the zone of reduced backscatter is monitored, preferably using high frequency ultrasound, to determine the flow rate or perfusion rate of the fluid. Spectral parameters of ultrasound return signals are evaluated to determine an estimate of contrast agent concentration and/or mean particle size.Type: GrantFiled: May 26, 1999Date of Patent: February 13, 2001Assignee: Riverside Research InstituteInventors: Frederic Louis Lizzi, Cheri Xiaoyu Deng