Abstract: A method of selectively enhancing the effect of photothermal vascular targeting on tumor regression by administration of a bioreductive agent is disclosed.

Abstract: A method of selectively enhancing the effect of photothermal vascular targeting on tumor regression by administration of a bioreductive agent is disclosed.

Abstract: The optical design of a laser resonator smooths out the intensity beam profile of the generated laser beam and prevents the formation of "hot-spots." The active laser resonator containing the active laser medium is optically coupled to a free space passive optical resonator to provide mixing and filtering of the spatial modes.

Abstract: A method is disclosed for producing a superimposed fast transient grating on a permanent holographic grating which provides high scattering ability, fast modulation response times, and the capability of writing and erasing signals therein. A glass host is doped with trivalent rare earth ions, and is then placed in the crossed field of two coherent radiation beams to resonantly pump the trivalent rare earth ions at a frequency in resonance with one of the absorption transitions thereof. This produces two types of laser induced gratings, a transient population grating associated with the excited rare earth ions, and a permanent holographic grating associated with a structural modification of the glass host. The superposition of these gratings result in a four wave mixing signal with enhanced strength and the capability of amplitude or frequency modulation.