Patents by Inventor Frederick F. Becker
Frederick F. Becker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9395331Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: July 22, 2015Date of Patent: July 19, 2016Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Publication number: 20150336111Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: July 22, 2015Publication date: November 26, 2015Inventors: Frederick F. BECKER, Peter GASCOYNE, Xiaobo WANG, Jody Valentine VYKOUKAL, Giovanni De GASPERIS
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Publication number: 20150321201Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: July 22, 2015Publication date: November 12, 2015Inventors: Frederick F. BECKER, Peter GASCOYNE, Xiaobo WANG, Jody Valentine VYKOUKAL, Giovanni De GASPERIS
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Publication number: 20150323497Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: July 22, 2015Publication date: November 12, 2015Inventors: Frederick F. BECKER, Peter GASCOYNE, Xiaobo WANG, Jody Valentine VYKOUKAL, Giovanni De GASPERIS
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Patent number: 8946409Abstract: Provided herein are polycyclic ?-lactam compounds, compositions thereof and methods for the treatment and prevention of diseases such as cancer, including pancreatic cancer and pancreatic cancers resistant to mainline chemotherapeutic agents.Type: GrantFiled: January 27, 2012Date of Patent: February 3, 2015Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F. Becker, Bimal K. Banik
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Publication number: 20150027895Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: August 5, 2014Publication date: January 29, 2015Inventors: Frederick F. BECKER, Peter GASCOYNE, Xiaobo WANG, Jody Valentine VYKOUKAL, Giovanni De GASPERIS
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Patent number: 8834810Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: July 10, 2012Date of Patent: September 16, 2014Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Publication number: 20140066423Abstract: Provided herein are polycyclic ?-lactam compounds, compositions thereof and methods for the treatment and prevention of diseases such as cancer, including pancreatic cancer and pancreatic cancers resistant to mainline chemotherapeutic agents.Type: ApplicationFiled: January 27, 2012Publication date: March 6, 2014Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Frederick F. Becker, Bimal K. Banik
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Publication number: 20130118903Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: July 10, 2012Publication date: May 16, 2013Inventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Patent number: 8216513Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: November 20, 2009Date of Patent: July 10, 2012Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F Becker, Peter Gascoyne, Xiaobo Wang, Jody Vykoukal, Giovanni De Gasperis
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Patent number: 7862702Abstract: Methods and apparatus for preparing a smear for cytopathology or other analysis. In a representative embodiment, cells of a sample are subjected to a dielectrophoretic force to segregate the cells into two or more zones of a surface. The particles are attached to the surface, thereby defining a “segregated smear.” The segregated smear is then fixed and stained for cytopathology analysis.Type: GrantFiled: July 24, 2006Date of Patent: January 4, 2011Assignee: Board of Regents, The University of Texas SystemInventors: Peter R. C. Gascoyne, Jody V. Vykoukal, Chandra Das, Frederick F. Becker
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Publication number: 20100084273Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: November 20, 2009Publication date: April 8, 2010Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Patent number: 7641779Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: May 23, 2005Date of Patent: January 5, 2010Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Patent number: 7105081Abstract: Methods and apparatus for preparing a smear for cytopathology or other analysis. In a representative embodiment, cells of a sample are subjected to a dielectrophoretic force to segregate the cells into two or more zones of a surface. The particles are attached to the surface, thereby defining a “segregated smear.” The segregated smear is then fixed and stained for cytopathology analysis.Type: GrantFiled: December 22, 2003Date of Patent: September 12, 2006Assignee: Board of Regents, The University of Texas SystemInventors: Peter R. C. Gascoyne, Jody V. Vykoukal, Chandra Das, Frederick F. Becker
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Patent number: 7033473Abstract: Methods and apparatuses for discriminating matter utilizing dielectrophoresis combined with magnetophoresis. A sample having one or more constituents is injected into an inlet port of a chamber. A carrier medium flow is initiated at the inlet port to establish a flow within the chamber. A dielectrophoretic force is generated to act on the constituents of the sample. A magnetophoretic force is generated to act on the constituents of the sample. The dielectrophoretic force and magnetophoretic forces are balanced to position the constituents within the chamber. The constituents are then collected at one or more outlet ports of the chamber according to the dielectric and magnetic characteristics of the constituents. The constituents may be collected as a function of time-of-exit from the chamber and/or position within the chamber.Type: GrantFiled: June 14, 2001Date of Patent: April 25, 2006Assignee: Board of Regents, University of TexasInventors: Peter R. C. Gascoyne, Jody V. Vykoukal, Frederick F. Becker
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Patent number: 6977033Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: July 10, 2001Date of Patent: December 20, 2005Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Vykoukal, Giovanni De Gasperis
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Patent number: 6893547Abstract: Methods and apparatuses for metered injection of a fluid packet. A vessel containing a fluid is pressurized to a pressure less than or equal to a hold-off pressure. The fluid is subjected to an extraction force to form the fluid packet and extract the fluid packet from the vessel onto a surface.Type: GrantFiled: June 14, 2001Date of Patent: May 17, 2005Assignee: Board of Regents, The University of Texas SystemInventors: Peter Gascoyne, Jody V. Vykoukal, Jon Schwartz, Frederick F. Becker
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Patent number: 6866762Abstract: A dielectric gate and related systems and methods for controlling fluid flow. A dielectric gate includes one or more electrodes coupled between an inlet fluid pathway and an outlet fluid pathway. The electrodes are configured to draw fluid from the inlet fluid pathway to the outlet fluid pathway in a precise manner by using dielectric forces arising from electrical signals applied to the electrodes.Type: GrantFiled: December 20, 2001Date of Patent: March 15, 2005Assignee: Board of Regents, University of Texas SystemInventors: Peter Gascoyne, Jon Schwartz, Jody V. Vykoukal, Frederick F. Becker
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Publication number: 20040178068Abstract: Methods and apparatus for preparing a smear for cytopathology or other analysis. In a representative embodiment, cells of a sample are subjected to a dielectrophoretic force to segregate the cells into two or more zones of a surface. The particles are attached to the surface, thereby defining a “segregated smear.” The segregated smear is then fixed and stained for cytopathology analysis.Type: ApplicationFiled: December 22, 2003Publication date: September 16, 2004Applicant: The University of Texas SystemInventors: Peter R.C. Gascoyne, Jody V. Vykoukal, Chandra Das, Frederick F. Becker
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Patent number: 6790330Abstract: Systems, apparatuses and methods for cell isolation and analysis. Cells are introduced into a dielectrophoretic prefilter including one or more trapping electrodes configured to trap at least a portion of the cells with a dielectrophoretic force. The cells trapped from the prefilter are directed into a dielectrophoretic field-flow fractionation separator coupled to the prefilter. The cells are discriminated by balancing a dielectrophoretic force (and optionally a magnetophoretic force) with a gravitational force to displace the cells to positions within a velocity profile in the separator. At least a portion of the cells are trapped as a function of the cells' time of emergence from the separator with two or more spiral electrode segments coupled to the separator.Type: GrantFiled: June 14, 2001Date of Patent: September 14, 2004Assignee: Board of Regents, The University of Texas SystemInventors: Peter Gascoyne, Jody V. Vykoukal, Frederick F. Becker