Abstract: The present invention provides a calibration device for an optical detector comprising a light emitting diode 1, and an electronic circuit 3 for driving the light emitting diode 1, wherein the electronic circuit 3 is a constant current generator configured to supply a constant driving current to the light emitting diode 1 in the range of 0.5 to 25 ?A. Furthermore, the present invention provides a setting device for setting at least one calibration point for a calibration device as described above. The setting device comprises a light detector 51 configured to output a signal representing the light emission intensity of a calibration device under examination, a controller 53 for controlling the constant driving current of the calibration device under examination, and a calibration point setting means 55 for setting at least one calibration point for the calibration device under examination.

Abstract: A device for imaging a bioluminescence reaction of a sample is provided, containing a reflector having a parametric form and extending about a first longitudinal axis (C), a receptacle into which a sample container with a second longitudinal axis can be inserted to be held therein, and a photo sensor with a photosensitive portion. The reflector has an opening through which the sample container can be inserted to a position where the sample container is held in the receptacle. The receptacle is arranged such that, when the sample container with the sample is held in the receptacle, the sample is surrounded by the reflector so that the light emitted from the sample due to the bioluminescence reaction is reflected by the reflector onto the photosensitive portion of the photo sensor. And an apparatus is provided including the device.

Abstract: The present invention provides a calibration device for an optical detector comprising a light emitting diode 1, and an electronic circuit 3 for driving the light emitting diode 1, wherein the electronic circuit 3 is a constant current generator configured to supply a constant driving current to the light emitting diode 1 in the range of 0.5 to 25 ?A. Furthermore, the present invention provides a setting device for setting at least one calibration point for a calibration device as described above. The setting device comprises a light detector 51 configured to output a signal representing the light emission intensity of a calibration device under examination, a controller 53 for controlling the constant driving current of the calibration device under examination, and a calibration point setting means 55 for setting at least one calibration point for the calibration device under examination.

Abstract: A camera for capturing an image of an object, for example an eye. The camera has at least two light sources and an image-sensing system having two image sensors. A multiple branch optical system transmits outgoing light from the light sources to the object, and transmits incoming light from the object to the image-sensing system. The multiple branch optical system includes an autofocusing element such as a variable power optical element that varies the focus of the incoming light. There is also an image display. There is a controller that controls the operation of the light sources, controls acquisition of images by the image-sensing system, and controls the display of images on the image display. The controller activates an autofocus light source and uses the resulting captured image to automatically adjust the image exposure parameters.

Abstract: This invention relates to a filtration apparatus and method for the separation of microscopic entities from a fluid (liquid or gas) and subsequent visual or imaging microscopic analysis of the entities separated thereon either directly or after treatment of the entities whilst on the apparatus in order to enhance their subsequent visualization and/or imaging. Such treatment can comprise reaction with reagents contained in other solutions that can be made to imbibe and/or pass through the filtration apparatus and which can be washed with solutions that can be made to imbibe and/or pass through the filtration apparatus. An example of a specific area of application is in the microbiological testing of fluids in order to detect, identify and/or enumerate microorganisms contained in a fluid test sample.

Abstract: A cartridge device for processing a sample mounted on a surface of or entrapped within the matrix of a support member and comprising a housing having a cavity therein and an aperture providing access for the introduction of said support member into said cavity so as to define two compartments when said support member is inserted therein, one of which compartments (called the first one) being defined by the sample bearing surface of the support member, an inner surface of the cavity and spacing means therebetween of such size, form and configuration that the dimension of said first compartment perpendicular to the sample bearing surface of the support member and the said inner surface of the cavity is of capillary dimensions, the other one compartment (called the second compartment) being defined by opposite surface(s) to the sample bearing surface of the support member and the remaining inner surface(s) of the said cavity, there being provided within said cavity elastically means engaging said support member

Abstract: A filtration member transfer apparatus is provided for transferring one or a plurality of discrete reaction or isolation zones such as filtration membranes from a sample isolation step to an analytical apparatus. The transfer apparatus includes a template, preferably which is electrically conductive, having holes or depressions of a size, shape and position corresponding to the reaction or isolation zones. An electrically conductive adhesive is exposed in the holes or depressions of the template.

Abstract: An affinity matrix and a method for the detection of low molecular weight compositions such as aflatoxins are provided utilizing specific monoclonal IgM antibody having an affinity constant not less than about 1.times.10.sup.9 liters per mole. Methods for the preparation and use of such affinity matrices are also given. The detection is rapid, accurate, reproducible, and allows for quantitative recovery of the composition of interest.