Patents by Inventor Frederick S. BUCKNER

Frederick S. BUCKNER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them
    Patent number: 11584744
    Abstract: The present disclosure is generally directed to compositions useful in the inhibition of MetRS and methods for treating diseases that are ameliorated by the inhibition of MetRS.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 21, 2023
    Assignee: University of Washington
    Inventors: Erkang Fan, Zhongsheng Zhang, Wenlin Huang, Frederick S. Buckner
  • INHIBITORS OF TYPE l METHIONYL-TRNA SYNTHETASE AND METHODS OF USING THEM
    Publication number: 20210155617
    Abstract: The present disclosure is generally directed to compositions useful in the inhibition of MetRS and methods for treating diseases that are ameliorated by the inhibition of MetRS.
    Type: Application
    Filed: June 22, 2018
    Publication date: May 27, 2021
    Inventors: Erkang FAN, Zhongsheng ZHANG, Wenlin HUANG, Frederick S. BUCKNER
  • Specific inhibitors of methionyl-tRNA synthetase
    Patent number: 10913736
    Abstract: The present disclosure is generally directed to compositions useful in the inhibition of MetRS and methods for treating diseases that are ameliorated by the inhibition of MetRS.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: February 9, 2021
    Assignee: University of Washington
    Inventors: Frederick S. Buckner, Ximena Barros Alvarez, Erkang Fan, John Robert Gillespie, Wilhelmus G.J. Hol, Wenlin Huang, Cho Yeow Koh, Ranae M. Ranade, Sayaka Shibata, Christophe L.M. Verlinde, Zhongsheng Zhang
  • Compounds for treatment of trypanosomes and neurological pathogens and uses thereof
    Patent number: 10399966
    Abstract: The present invention relates to novel compounds that cross the blood-brain barrier and are effective inhibitors of neurological pathogens such as trypanosomes. The invention further relates to the use of these compounds for treating disorders related to trypanosomes and neurological pathogens.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: September 3, 2019
    Assignees: University of Washington, The University of North Carolina at Chapel Hill
    Inventors: Richard Ray Tidwell, Donald Alan Patrick, Frederick S. Buckner, Michael H. Gelb, John R. Gillespie, Daniel Gedder Silva
  • COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF
    Publication number: 20190031649
    Abstract: The present invention relates to novel compounds that cross the blood-brain barrier and are effective inhibitors of neurological pathogens such as trypanosomes. The invention further relates to the use of these compounds for treating disorders related to trypanosomes and neurological pathogens.
    Type: Application
    Filed: January 20, 2017
    Publication date: January 31, 2019
    Applicants: The University of North Carolina at Chapel Hill, University of Washington
    Inventors: Richard Ray Tidwell, Donald Alan Patrick, Frederick S. Buckner, Michael H. Gelb, John R. Gillespie, Daniel Gedder Silva
  • SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE
    Publication number: 20170275279
    Abstract: The present disclosure is generally directed to compositions useful in the inhibition of MetRS and methods for treating diseases that are ameliorated by the inhibition of MetRS.
    Type: Application
    Filed: August 21, 2015
    Publication date: September 28, 2017
    Inventors: Frederick S. BUCKNER, Ximena Barros ALVAREZ, Erkang FAN, John Robert GILLESPIE, Wilhelmus G.J. HOL, Wenlin HUANG, Cho Yeow KOH, Ranae M. RANADE, Sayaka SHIBATA, Christophe L.M. VERLINDE, Zhongsheng ZHANG