Patents by Inventor Frederick Sheedy

Frederick Sheedy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MiR-33 inhibitors and uses thereof to decrease inflammation
    Patent number: 9241950
    Abstract: The inhibition of miRNA miR-33 is shown to promote the polarization of macrophages from an M1 to an M2 phenotype. MiR-33 inhibitors are therefore useful for treating inflammation in subjects. Endogenous microRNAs can be silenced using antagomirs. The miR-33 inhibitor is preferably an antagomir having a single-stranded nucleic acid sequence that is complementary to at least 12 contiguous nucleotides in miR-33 and therefore forms a duplex with miR-33 under physiological conditions.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: January 26, 2016
    Assignee: New York University
    Inventors: Kathryn J. Moore, Katey J. Rayner, Frederick Sheedy, Carlos Fernandez-Hernando, Yajaira Suarez
  • miR-33 Inhibitors and Uses Thereof to Decrease Inflammation
    Publication number: 20140080899
    Abstract: The inhibition of miRNA miR-33 is shown to promote the polarization of macrophages from an M1 to an M2 phenotype. MiR-33 inhibitors are therefore useful for treating inflammation in subjects. Endogenous microRNAs can be silenced using antagomirs. The miR-33 inhibitor is preferably an antagomir having a single-stranded nucleic acid sequence that is complementary to at least 12 contiguous nucleotides in miR-33 and therefore forms a duplex with miR-33 under physiological conditions.
    Type: Application
    Filed: April 30, 2012
    Publication date: March 20, 2014
    Applicant: NEW YORK UNIVERSITY
    Inventors: Kathryn J. Moore, Katey J. Rayner, Frederick Sheedy, Carlos Fernandez-Hernando, Yajaira Suarez