Abstract: A fluid connector includes an extending section having a spiked end to pierce a container port. The extending section includes at least one air conduit and at least one fluid conduit therethrough. The extending section further includes first and second abutment members. The first abutment member is adapted to abut a first or air side of the container port upon piercing of the container port, and the second abutment member, which is spaced from the first abutment member, is adapted to abut a second or fluid side of the container port. The fluid connector can further include grasping members extending from the extending section to facilitate rotation of the extending section relative to the container port during piercing thereof. The fluid connector can also include a check valve in fluid connection with the at least one air conduit. The check valve may be positioned within the extending section.

Abstract: An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

Abstract: A medical connector includes a body defining a lumen for fluid flow through the medical connector. The medical connector includes a luer member and an annular member disposed about the luer member. The annular member includes internal and/or external engagement structures. The medical connector may be provided on the outlet of a syringe or on a catheter. A fluid path is disclosed including a first section and a second section. The first and second sections may each include a medical connector to provide a removable connection with a syringe and a catheter, respectively. The medical connector may provide a removable connection between the first and second sections. A fluid delivery system is disclosed including an injector, a syringe operatively associated with the injector, and a fluid path connecting the syringe and a source of injection. The medical connector may provide a removable connection between the syringe and fluid path.

Abstract: A fluid path set including a multi-patient use section adapted for connection with a pump device and a source of injection fluid, and a per-patient use section adapted for removable fluid communication with the multi-patient use section. The per-patient use section includes a pressure isolation mechanism having a first port adapted for connection to the pump device via the multi-patient use section, a second port adapted for connection to a patient, and a pressure isolation port adapted for connection to a source of medical fluid via the multi-patient use section. The per-patient use section includes a valve member biased to a normally open position permitting fluid communication between the first port, the second port, and the pressure isolation port, and movable to a closed position to close the pressure isolation port when fluid pressure reaches a predetermined pressure level sufficient to overcome a biasing force applied to the valve member.

Abstract: A fluid path set for use with an injection device has a single-patient disposable set and a patency check device. A proximal end of the single-patient disposable set is configured for connecting with the injection device. The patency check device has a proximal end configured for connecting with a distal end of the single-patient disposable set and a distal end configured for connecting with a patient fluid delivery device. The patency check device has a body extending between the proximal end and the distal end. The body has a reversibly expandable interior chamber configured for drawing fluid through the patient fluid delivery device during a patency check. The patency check device further has a locking mechanism configured for controlling the volume of the interior chamber during an injection procedure.

Abstract: A container adapted to store and transport an injectate is disclosed. The container includes a divider which extends from an open top end toward a closed bottom end, the divider spaced apart from the closed bottom end to define an opening and separating the container into a first fluid path on a first side of the divider through which fluid can enter the container through the inlet port and a second fluid path on a second side of the divider through which fluid can enter the opening and exit the container through the outlet port. The second fluid path includes at least one filter between the opening and the open top end through which fluid can pass from the first fluid path to the second fluid path but through which at least one component of the injectate cannot pass.

Abstract: A catheter including an outer conduit and an inner conduit positioned within the outer conduit, the inner conduit having a smaller diameter that that of the outer conduit. A volume between the outer conduit and the inner conduit define a first lumen which may deliver a first fluid to a patient, and an inside diameter of the inner conduit defines a second lumen which may deliver a second fluid to the patient such that the fluid flow of the first fluid and the second fluid exiting the catheter has a flow profile where the first fluid surrounds the second fluid and the second fluid is prevented from contact with inner walls of a blood vessel of the patient in a vicinity of a tip of the catheter.

Abstract: An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.

Abstract: A fluid connector includes an extending section including a spiked end to pierce the container port. The extending section includes at least one air conduit and at least one fluid conduit therethrough. The extending section further includes a first abutment member and second abutment member. The first abutment member is adapted to abut a first or air side of the container port upon piercing of the container port. The second abutment member is spaced from the first abutment member and is adapted to abut a second or fluid sided of the container port. The fluid connector can further include grasping members extending from the extending section to facilitate rotation of the extending section relative to the container port during piercing thereof. The fluid connector can also include a check valve in fluid connection with the air line. In several embodiments, the check valve is positioned within the extending section.

Abstract: A medical connector for delivering a liquid at a high flow rate to a patient. The connector includes a gas inlet passage that is configured for connecting to a source of pressurized gas, a spike configured for piercing a stopper of a container, and a liquid outlet passage in fluid communication with the spike. The liquid outlet passage is configured for connecting to tubing through which the liquid in the container can be administered to a patient. The spike has a shield having a first closed end and a second open end such that the first closed end is breakable by the spike when the spike is inserted through the stopper of the container, and the second open end has an annular elastomeric member that attaches to the spike via compressive pressure applied by the annular elastomeric member.

Abstract: A hazardous fluid handling system which includes a housing having a radiation shielded internal chamber disposed therein which may accommodate a container holding a radioactive fluid, one or more radioactivity detectors positioned within the shielded internal chamber in operational proximity to the radioactive fluid in the container, and a dosimeter control device electronically coupled to the radioactivity detector(s) is disclosed. The dosimeter control device is operational for determining information regarding the radioactive fluid in the container based on individual measurements received from the one or more radioactivity detectors. The hazardous fluid handling system may be integrated into a patient support platform which includes a patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with the patient, and an integrated system controller.

Abstract: A system for delivering fluid to a patient includes a container suitable for holding a fluid and an enclosure to shield the fluid. The system further includes a pump device capable of pumping fluid from the container and delivering the fluid to the patient, and the container adapted to be attachable to the pump device.

Abstract: A hazardous fluid transport container and a hazardous fluid delivery system are disclosed. The hazardous fluid transport container includes a housing enclosing an at least partially shielded enclosure. First and second fluid path elements are disposed within the housing, with the first fluid path element and second fluid path element fluidly coupled together. A pump unit may be provided for dispensing fluid from the first and second fluid path elements optionally into a third fluid path element. Also, methods for priming the hazardous fluid transport container and for mitigating laminar flow injection bolus spreading are disclosed. Additionally, disclosed is a radioactive fluid transport container for a syringe or other container. The radioactive fluid transport container allows the syringe or container to be used in an injection procedure without removal from the container.

Abstract: A system for delivering fluid to a patient includes a hazardous material enclosure suitable for holding a first container comprising a first fluid, and a pump device capable of pumping the first fluid from the first container and a second fluid from a second container. The hazardous materials enclosure has a cap which includes a flexible sealing member that cooperates with the first container to create a biohazard seal during connection of the first container to the cap. The system further includes a mixing device associated with the pump for mixing the first and second fluids for delivering the fluid mixture to the patient.

Abstract: A medical connector includes a body defining a lumen for fluid flow through the medical connector. The medical connector includes a luer member and an annular member disposed about the luer member. The annular member includes internal and/or external engagement structures. The medical connector may be provided on the outlet of a syringe or on a catheter. A fluid path is disclosed including a first section and a second section. The first and second sections may each include a medical connector to provide a removable connection with a syringe and a catheter, respectively. The medical connector may provide a removable connection between the first and second sections. A fluid delivery system is disclosed including an injector, a syringe operatively associated with the injector, and a fluid path connecting the syringe and a source of injection. The medical connector may provide a removable connection between the syringe and fluid path.

Abstract: A system includes at least one pressurizing mechanism, a fluid path adapted to be placed in operative connection with the pressurizing mechanism to deliver an injectate to a patient, wherein the injectate includes cells, a control system operably associated with the at least one pressurizing mechanism; and at least one parameter generation system in operative connection with the control system. The parameter generation system includes an input system to receive data of a type of cells to be injected and is adapted to generate at least one parameter for the injection procedure at least in part on the basis of the data of the type of cells. The at least one parameter for the injection procedure may, for example, be a variable associated with the injectate, a variable associated with an injection protocol or a variable associated with at least one component of the fluid path.

Abstract: A medical connector includes a body defining a lumen for fluid flow through the medical connector. The medical connector includes a luer member and an annular member disposed about the luer member. The annular member includes internal and/or external engagement structures. The medical connector may be provided on the outlet of a syringe or on a catheter. A fluid path is disclosed including a first section and a second section. The first and second sections may each include a medical connector to provide a removable connection with a syringe and a catheter, respectively. The medical connector may provide a removable connection between the first and second sections. A fluid delivery system is disclosed including an injector, a syringe operatively associated with the injector, and a fluid path connecting the syringe and a source of injection. The medical connector may provide a removable connection between the syringe and fluid path.

Abstract: An injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injection, a fluid path in fluid communication with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection therewith. An injection system for use in angiography includes a source of saline, a pump in fluid connection with the source of saline to pressurized the saline, a source of contrast, a contrast valve in fluid connection with the source of contrast, a powered injector in fluid connection with the contrast valve, and a pressure isolation mechanism.

Abstract: A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.

Abstract: An injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injection, a fluid path in fluid communication with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection therewith. An injection system for use in angiography includes a source of saline, a pump in fluid connection with the source of saline to pressurized the saline, a source of contrast, a contrast valve in fluid connection with the source of contrast, a powered injector in fluid connection with the contrast valve, and a pressure isolation mechanism.