Abstract: Provided herein is a method of administering levoketoconazole, or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the subject is also being administered a multidrug and toxin extrusion transporter 1 (MATE1) substrate or an organic cation transporter 2 (OCT2) substrate.

Abstract: Provided herein is a method of administering levoketoconazole, or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the subject is also being administered a multidrug and toxin extrusion transporter 1 (MATE1) substrate or an organic cation transporter 2 (OCT2) substrate.

Abstract: Provided herein is a method of administering levoketoconazole, or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the subject is also being administered a multidrug and toxin extrusion transporter 1 (MATE1) substrate or an organic cation transporter 2 (OCT2) substrate.

Abstract: A controller for a valve assembly that is configured to meet requirements for use in hazardous areas. These configurations may regulate flow of instrument air to a pneumatic actuator to operate a valve. The controller may comprise enclosures, including a first enclosure and a second enclosure, each having a peripheral wall forming an interior space, and circuitry comprising a barrier circuit disposed in the interior space of one of the enclosures that power limits digital signals that exits that enclosure. In one example, the peripheral wall of enclosures are configured to allow instrument air into the interior space of the first enclosure but to prevent instrument air from the interior space of the second enclosure.

Abstract: Provided herein is a method of administering levoketoconazole, or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the subject is also being administered a multidrug and toxin extrusion transporter 1 (MATE1) substrate or an organic cation transporter 2 (OCT2) substrate.

Abstract: Provided herein is a method of administering levoketoconazole, or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the subject is also being administered a multidrug and toxin extrusion transporter 1 (MATE1) substrate or an organic cation transporter 2 (OCT2) substrate.

Abstract: Provided herein is a method of administering levoketoconazole, or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the subject is also being administered a multidrug and toxin extrusion transporter 1 (MATE1) substrate or an organic cation transporter 2 (OCT2) substrate.

Abstract: Provided herein is a method of administering levoketoconazole, or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the subject is also being administered a multidrug and toxin extrusion transporter 1 (MATE1) substrate or an organic cation transporter 2 (OCT2) substrate.

Abstract: A controller for a valve assembly that is configured to meet requirements for use in hazardous areas. These configurations may regulate flow of instrument air to a pneumatic actuator to operate a valve. The controller may comprise enclosures, including a first enclosure and a second enclosure, each having a peripheral wall forming an interior space, and circuitry comprising a barrier circuit disposed in the interior space of one of the enclosures that power limits digital signals that exits that enclosure. In one example, the peripheral wall of enclosures are configured to allow instrument air into the interior space of the first enclosure but to prevent instrument air from the interior space of the second enclosure.

Abstract: A controller for a valve assembly that is configured to meet requirements for use in hazardous areas. These configurations may regulate flow of instrument air to a pneumatic actuator to operate a valve. The controller may comprise enclosures, including a first enclosure and a second enclosure, each having a peripheral wall forming an interior space, and circuitry comprising a barrier circuit disposed in the interior space of one of the enclosures that power limits digital signals that exits that enclosure. In one example, the peripheral wall of enclosures are configured to allow instrument air into the interior space of the first enclosure but to prevent instrument air from the interior space of the second enclosure.

Abstract: A controller for a valve assembly that is configured to meet requirements for use in hazardous areas. These configurations may regulate flow of instrument air to a pneumatic actuator to operate a valve. The controller may comprise enclosures, including a first enclosure and a second enclosure, each having a peripheral wall forming an interior space, and circuitry comprising a barrier circuit disposed in the interior space of one of the enclosures that power limits digital signals that exits that enclosure. In one example, the peripheral wall of enclosures are configured to allow instrument air into the interior space of the first enclosure but to prevent instrument air from the interior space of the second enclosure.

Abstract: A system and a method for capturing, storing and replaying data describing application of an event-based process to an event are described. As an event processing engine processes an input event, specified data is captured by a store monitor included in the event processing engine. Hence, while the event processing engine processes an input event, data describing the event processing is contemporaneously captured without affecting processing of the input event. The captured data is then stored for later access and can be used later simulate or analyze the event processing. In one embodiment, the stored data is also classified or grouped based on one or more grouping criteria (e.g., event type, timestamp) to simplify later access to the data.

Abstract: A system and a method for capturing, storing and replaying data describing application of an event-based process to an event are described. As an event processing engine processes an input event, specified data is captured by a store monitor included in the event processing engine. Hence, while the event processing engine processes an input event, data describing the event processing is contemporaneously captured without affecting processing of the input event. The captured data is then stored for later access and can be used later simulate or analyze the event processing. In one embodiment, the stored data is also classified or grouped based on one or more grouping criteria (e.g., event type, timestamp) to simplify later access to the data.