Abstract: The invention provides novel 6-heterocyclyl-4-morpholin-4-yl-pyridine-2-one compounds of formula (I), pharmaceutical compositions containing such compounds, and methods for using such compounds in treatment of diseases including cancer, diabetes, inflammatory disease, neurodegenerative disorders, cardiovascular disorders and viral infections; wherein R1, R2, R3 and A are as defined in the specification.

Abstract: The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula: wherein A, X, Y, Z, Q, R1, R2, R3, R4, R5, and n are described herein.

Abstract: A fuel supply system for small two-stroke internal combustion engines for e.g. chain saws, line trimmers and similar hand-held power-tools including a diaphragm carburetor (20) equipped with a purging system (80a, 81a) or priming system (80b, 81b) for facilitating starting of the engine (1). Downstream of the diaphragm (30), the carburetor has a fuel valve (60) with a fuel cavity (73), which when the valve is not closed being connected via a fuel conduit (37) to a fuel nozzle (35, 36) in a main air passage (21) in the carburetor. The purging system or priming system including a fuel line (80a; 80b), which is provided with a manually operated pump (81a; 81b) and is connected between a fuel tank (26) and either the fuel cavity (73) or the fuel conduit (37).

Abstract: A magnet holder (10) for use in an analogous or digital throttle position sensor for sensing the angle of a butterfly valve in a fuel supply unit of an internal combustion engine, said magnet holder (10) including a throttle lever member (11) adapted to be fixed to a shaft of the butterfly valve and carrying at least one magnet (17). A recess (12) for the magnet (17), or for each magnets if more than one magnet is used, is provided in the throttle lever member (11), the magnet (17) is located in said recess (12), or the magnets are located in said recesses if more than one magnet is used, and throttle lever member material (18) located around an entrance to the recess (12) or entrances to the recesses is staked over the magnet (17) or magnets, respectively, to cover each magnet (17) sufficiently to retain it in its associated recess (12).

Abstract: A magnet holder (10) for use in an analogous or digital throttle position sensor for sensing the angle of a butterfly valve in a fuel supply unit of an internal combustion engine, said magnet holder (10) including a throttle lever member (11) adapted to be fixed to a shaft of the butterfly valve and carrying at least one magnet (17). A recess (12) for the magnet (17), or for each magnets if more than one magnet is used, is provided in the throttle lever member (11), the magnet (17) is located in said recess (12), or the magnets are located in said recesses if more than one magnet is used, and throttle lever member material (18) located around an entrance to the recess (12) or entrances to the recesses is staked over the magnet (17) or magnets, respectively, to cover each magnet (17) sufficiently to retain it in its associated recess (12).

Abstract: A fuel supply system for small two-stroke internal combustion engines for e.g. chain saws, line trimmers and similar hand-held power-tools including a diaphragm carburetor (20) equipped with a purging system (80a, 81a) or priming system (80b, 81b) for facilitating starting of the engine (1). Downstream of the diaphragm (30), the carburetor has a fuel valve (60) with a fuel cavity (73), which when the valve is not closed being connected via a fuel conduit (37) to a fuel nozzle (35, 36) in a main air passage (21) in the carburetor. The purging system or priming system including a fuel line (80a; 80b), which is provided with a manually operated pump (81a; 81b) and is connected between a fuel tank (26) and either the fuel cavity (73) or the fuel conduit (37).