Abstract: The use of a genetic method to down-regulate RBO/EFR3/EFR3A/EFR3B proteins, TTC7 protein or PI4KIII? enzyme protein which interacts with RBO/EFR3/EFR3A/EFR3B proteins and TTC7 protein, or the use of a drug to inhibit PI4KIII? protein kinase activity reduces the accumulation of A?42 within neurons and age-dependent synaptic transmission failure and other obstacles in a fruit fly AD model, and obtains an effect of improving the learning and memory abilities of AD model mice. Provided is a method for using an RBO/EFR3/EFR3A/EFR3B inhibitor, a TTC7 inhibitor and a PI4KIII? inhibitor to treat Alzheimer's disease. Also provided is a method for screening a drug treating Alzheimer's disease by whether A? secretion by nerve cells is promoted or not.

Abstract: The invention provides a special launching carrier with variable position platform and a method for bridge erection using the same. The special launching carrier with variable position platform comprises a special carrier for erection bridge beam and an under-bridge machine with platform. The special carrier for erecting beam comprises a main beam, a front wheel group, a rear wheel group and a lifting device; the under-bridge machine with platform comprises a under-bridge, a rotatable rear leg, a front roller, a middle roller, a rear roller and an erecting trolley arranged on the under-bridge, and the variable position platforms are installed on both sides of tail portion of the under-bridge. When erecting bridge beam, the front wheel group moves onto the variable position platforms, which may be elevated and folded in terms of conditions of the first and last spans of different bridges, so that the bridge erection is achieved.

Abstract: The invention provides a special launching carrier with variable position platform and a method for bridge erection using the same. The special launching carrier with variable position platform comprises a special carrier for erection bridge beam and an under-bridge machine with platform. The special carrier for erecting beam comprises a main beam, a front wheel group, a rear wheel group and a lifting device; the under-bridge machine with platform comprises a under-bridge, a rotatable rear leg, a front roller, a middle roller, a rear roller and an erecting trolley arranged on the under-bridge, and the variable position platforms are installed on both sides of tail portion of the under-bridge. When erecting bridge beam, the front wheel group moves onto the variable position platforms, which may be elevated and folded in terms of conditions of the first and last spans of different bridges, so that the bridge erection is achieved.