Patents by Inventor Fumio Toda

Fumio Toda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5618978
    Abstract: A method of producing a choline having a high purity without containing by-products by using a molecule-inclusion complex of the choline as a starting material. A choline inclusion complex without containing by-products is obtained by reacting an aqueous solution of the choline containing, as by-products, those cholines to which are added ethylene oxides with host molecules such as of 1,1'-bis-.beta.-naphthol, and is further reacted with a carbon dioxide gas in order to obtain an aqueous solution of a choline carbonate and/or a choline bicarbonate of a high purity, which is then subjected to the electrolysis using a cation-exchange membrane as a diaphragm, in order to obtain an aqueous solution of the choline of a high purity without containing by-products. The choline that is obtained is a strongly basic compound having a high purity and is very useful as a photoresist-developing solution.
    Type: Grant
    Filed: March 26, 1996
    Date of Patent: April 8, 1997
    Assignee: Japan Hydrazine Co., Ltd.
    Inventors: Shunji Hyoda, Youichi Hasegawa, Fumio Toda
  • Patent number: 5395977
    Abstract: A process for producing optically active 4-hydroxy-2-cyclopentenone [1] which comprises reacting 4-hydroxy-2-cyclopentenone represented by the formula: ##STR1## with an optically active propargyl alcohol derivative represented by the general formula: ##STR2## wherein R and R.sup.1 each independently represent a halogenated phenyl group, an alkylphenyl group, or an alkyl group which may be substituted with one or more halogen atom(s), and * indicates an asymmetric carbon atom, to form an optically active complex [3] consisting essentially of optically active 4-hydroxy-2-cyclopentenone represented by the formula [1] ##STR3## wherein * indicates an asymmetric carbon atom, and the optically active propargyl alcohol derivative [2], and then decomposing the optically active complex [3].
    Type: Grant
    Filed: March 12, 1993
    Date of Patent: March 7, 1995
    Assignee: Sumitomo Chemical Company, Ltd.
    Inventors: Fumio Toda, Yorihiko Inoue, Masayoshi Minai
  • Patent number: 5395985
    Abstract: A compound represented by the general formula (I) and a separating agent comprising the same: ##STR1## wherein Ar and Ar' are each an aromatic group; and the positional relationship of the two substituents on the central benzene ring may be any of ortho, meta and para.The above compound is effective in the separation and purification of many compounds to and enables the provision of various compounds (such as intermediates of drugs) which are useful in the field of fine chemicals, particularly optically active substances, at high purities and in large amounts.
    Type: Grant
    Filed: March 4, 1994
    Date of Patent: March 7, 1995
    Assignee: Daicel Chemical Industries, Ltd.
    Inventor: Fumio Toda
  • Patent number: 5334776
    Abstract: A compound represented by the general formula (I) and a separating agent comprising the same: ##STR1## wherein Ar and Ar' are each an aromatic group; and the positional relationship of the two substituents on the central benzene ring may be any of ortho, meta and para.The above compound is effective in the separation and purification of many compounds and enables the provision of various compounds (such as intermediates of drugs) which are useful in the field of fine chemicals, particularly optically active substances, at high purities and in large amounts.
    Type: Grant
    Filed: March 12, 1993
    Date of Patent: August 2, 1994
    Assignee: Daicel Chemical Industries, Ltd.
    Inventor: Fumio Toda
  • Patent number: 5306844
    Abstract: A d- or l-tartaric acid amide derivative serving as a host compound and a method of producing the amide derivative which combines with a guest compound to form a clathrate compound and which is expressed by the following Formula (A) or (B): ##STR1##
    Type: Grant
    Filed: May 11, 1990
    Date of Patent: April 26, 1994
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Fumio Toda, Koichi Tanaka
  • Patent number: 5276214
    Abstract: A biphenyl compound having the formula (I) is newly separated into its optical active compound, and useful as an optically separating agent: ##STR1## wherein W, X and Y are each an atom or atomic group selected from among H, F, Cl, Br, I, CH.sub.3, CF.sub.3, OH, OCH.sub.3, NH.sub.2 and N(CH.sub.3).sub.2 and Z is an atom or atomic group selected from among Cl, Br, I, CH.sub.3 and OCH.sub.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: January 4, 1994
    Assignee: Daicel Chemical Industries, Ltd.
    Inventor: Fumio Toda
  • Patent number: 5202504
    Abstract: A biphenyl compound having the formula (I) is newly separated into its optical active compound and useful as an optically separating agent: ##STR1## wherein W, X and Y are each an atom or atomic group selected from among H, F, Cl, Br, I, CH.sub.3, CF.sub.3, OH, OCH.sub.3, NH.sub.2 and N(CH.sub.3).sub.2 and Z is an atom or atomic group selected from among Cl, Br, I, CH.sub.3 and OCH.sub.
    Type: Grant
    Filed: January 25, 1991
    Date of Patent: April 13, 1993
    Assignee: Daicel Chemical Industries, Ltd.
    Inventor: Fumio Toda
  • Patent number: 5091400
    Abstract: 2,2'-Bis(.alpha.-hydroxydiphenylemthyl)biphenyl of formula: ##STR1## Clathrate compound is composed of the above compound as the host compound and a microbicide, 5-chloro-2-methyl-4-isothiazolin-3-one as the guest compound. The compound is formed such that, where diphenic acid is reacted with an alcohol for diesterification and then reacted with a Grignard reagent comprising a phenylmagnesium halide.
    Type: Grant
    Filed: August 7, 1990
    Date of Patent: February 25, 1992
    Assignee: Kurita Water Industries Ltd.
    Inventors: Minoru Yagi, Fumio Toda
  • Patent number: 5043495
    Abstract: A process of separation and purification of a propargyl alcohol which comprises treating a propargyl alcohol represented by Formula (I): ##STR1## wherein each of R.sub.1 and R.sub.2 represents a substituent which is different from each other, and is selected from the group consisting of a C.sub.1 -C.sub.8 alkyl group, a phenyl group; a halophenyl group, a phenyl group having at least one methyl substituent, an aralkyl group and a cycloalkyl group,which is chemically or optically impure,with a tertiary diamine represented by Formula (II): ##STR2## wherein each of R.sub.3, R.sub.4, R.sub.5 and R.sub.6 may be the same or different and represents an aralkyl group or an alkyl group having 1 to 6 carbon atoms; and R.sub.3, R.sub.4, R.sub.5 and R.sub.
    Type: Grant
    Filed: January 30, 1990
    Date of Patent: August 27, 1991
    Assignee: Ube Industries, Ltd.
    Inventors: Fumio Toda, Koichi Tanaka, Kikuo Ataka
  • Patent number: 5041620
    Abstract: A method for producing an optically active 2-cyclopenten-4-one-1-ol ester useful as an intermediate for medicines, agricultural chemicals and represented by the general formula (I), ##STR1## wherein R represents a saturated or unsaturated aliphatic hydrocarbon residue which may or may not be substituted with a halogen atom, and a mark * represents an asymmetric carbon,which comprises bringing a 2-cyclopenten-4-one-1-ol ester represented by the general formula ##STR2## wherein R represents a saturated or unsaturated aliphatic hydrocarbon residue which may or may not be substituted with a halogen atom, into contact with an optically active 1,6-diphenyl-2,4-hexadiyne-1,6-diol derivative represented by the general formula (II), ##STR3## wherein R' represents a halogenated phenyl, lower alkylphenyl, naphthyl or tertiary lower alkyl group, and a mark * represents an asymmetric carbon,in an organic solvent to obtain an optically active cyclopentenone ester complex which is a bound product of the optically active 2-c
    Type: Grant
    Filed: August 4, 1986
    Date of Patent: August 20, 1991
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Fumio Toda, Masayoshi Minai
  • Patent number: 4976834
    Abstract: An optically active substance having an optical purity of at least 50% e.e. is obtained by an asymmetric photochemical reaction by converting a starting, achiral material in a chiral crystalline form and irradiating light to the chiral crystalline form to effect the photocyclization of the starting material.
    Type: Grant
    Filed: March 28, 1988
    Date of Patent: December 11, 1990
    Assignee: Daicel Chemical Industries, Ltd.
    Inventor: Fumio Toda
  • Patent number: 4962274
    Abstract: A process for the separation of an alkyl-substituted naphthalene from a mixture containing the desired alkyl-substituted naphthalene and at least one isomer thereof comprises placing 9,9'-bianthracene in contact with the mixture to form a clathrate complex of the formula ##STR1## wherein A represents 2-methylnaphthalene, 2-isopropyl-naphthalene of 2,6-diisopropylnaphthalene, collecting the clathrate complex by filtration, subjecting the clathrate complex to thermal decomposition, and then recovering the alkyl-substituted naphthalene derivative.
    Type: Grant
    Filed: September 7, 1989
    Date of Patent: October 9, 1990
    Assignee: Kureha Kagaku Kogyo K.K.
    Inventor: Fumio Toda
  • Patent number: 4918190
    Abstract: Disclosed are a crystalline complex compound of a propargyl alcohol represented by Formula (I): ##STR1## wherein each of R.sub.1 and R.sub.2 represents a substituent which is different from each otherand a tertiary diamine represented by Formula (II): ##STR2## wherein A represents a group having two carbon atoms as a chain member which may be branched; each of R.sub.3, R.sub.4, R.sub.5 and R.sub.6 may be the same or different and represents an aralkyl group or an alkyl group having 1 to 6 carbon atoms; and A, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 may be bonded to each other,and a process of separation and purification of the propargyl alcohol using the crystalline complex compound described above.
    Type: Grant
    Filed: July 30, 1987
    Date of Patent: April 17, 1990
    Assignee: Ube Industries, Ltd.
    Inventors: Fumio Toda, Koichi Tanaka, Kikuo Ataka
  • Patent number: 4898654
    Abstract: Disclosed is a method of producing an optically active .beta.-lactam derivative of the formula ##STR1## comprising irradiating with light, in solid phase, an inclusion complex of a compound of the formula ##STR2## with an optically active host compound.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: February 6, 1990
    Assignee: Otsuka Kagaku Kabushiki Kaisha
    Inventors: Fumio Toda, Kouichi Tanaka, Masatoshi Taniguchi, Michio Sasaoka
  • Patent number: 4841081
    Abstract: A method of optically resolving a racemate, or a diastereomeric mixture, of a substituted or unsubstituted glycidyl ester or ether compound having at least one glycidylic structure represented by the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, independently from each other, represent H or CH.sub.3, and 1 to 3 asymmetric carbon atoms in the molecule, or a racemate of a beta-dihalohydrin ester compound, which comprises contacting said racemate or diastereomeric mixture with an optically active form of a compound having the following formula (I) ##STR2## wherein X represents a halogen atom, to form an inclusion complex compound having the optically active compound of formula (I) as a host, and separating the resulting complex compound.
    Type: Grant
    Filed: October 14, 1986
    Date of Patent: June 20, 1989
    Assignee: Osaka Soda Co., Ltd.
    Inventors: Fumio Toda, Koichi Tanaka, Tetsuya Nakata
  • Patent number: 4818771
    Abstract: Diphenic acid bis(dicyclohexylamide) represented by the following formula: ##STR1## A process for producing diphenic acid bis(dicyclohexylamide) represented by the above formula, which comprises dimerizing a diazonium salt of o-aminobenzoic acid in the presence of a reducing agent, followed by acidification to give 2,6'-dicarboxylbiphenyl; converting this dicarboxylic acid to 2,6'-dichloroformylbiphenyl by chlorination; and reacting this acid chloride with dicyclohexylamine.Sustained release antimicrobial compositions comprising a clathrate compound consisting of a microbial agent and diphenic acid bis(dicyclohexylamide) represented by the above formula.
    Type: Grant
    Filed: December 12, 1986
    Date of Patent: April 4, 1989
    Assignee: Kurita Water Industries, Ltd.
    Inventors: Fumio Toda, Ayako Sekikawa, Hideo Sugi, Kenji Tahara
  • Patent number: 4785111
    Abstract: This invention provides novel N-cyclohexyl-polycarboxamide compounds having inclusion power for a variety of compounds, the N-cyclohexyl-polycarboxamide compound being of the general formula ##STR1## where R is a benzene ring, an ethylidene group, a benzylidene group, a 1,2-cyclohexylene group, a 1,2-cyclohexenylene-4 group, or a 2,3-, 2,5- or 2,6-pyridinediyl group, and n is equal to 2, 3 or 4 when R is a benzene ring, and equal to 2 when R is one of the aforesaid groups excluding a benzene ring. These compounds exhibit the host function of taking up a variety of compounds as guest compounds to form inclusion complexes, and can be utilized for the separation and purification thereof.
    Type: Grant
    Filed: March 10, 1986
    Date of Patent: November 15, 1988
    Assignee: Mitsubishi Corporation
    Inventor: Fumio Toda
  • Patent number: 4780317
    Abstract: A sustained release antimicrobial agent comprises a clathrate compound composed of a water-soluble microbicide and at least one of the compounds shown at (I) to (V) below:(I) 1,1'-bi-2-naphthol;(II) 1,1,4,4-tetraphenyl-2-butyn-1,4-diol;(III) 9,10-di(4-methylphenyl)-9,10-dihydroznthracene-9,10-diol;(IV) 1,1-bis(4-hydroxyphenyl)-cyclohexane; and(V) 1,1,6,6-tetra(2,4-dimethylphenyl)-2,4-hexadiyne-1,6-diol.A method which uses it for preventing the fouling of a water system is also disclosed.
    Type: Grant
    Filed: January 22, 1987
    Date of Patent: October 25, 1988
    Assignee: Kurita Water Industries Ltd.
    Inventors: Ayako Sekikawa, Hideo Sugi, Kenji Tahara, Fumio Toda
  • Patent number: 4769502
    Abstract: Alkynol type compounds of the following formula (I): ##STR1## [wherein R.sub.1 -R.sub.5 and R.sub.6 -R.sub.10 each represent hydrogen atoms or lower alkyl group and R.sub.11 represents a lower alkyl group or a group of the formula: ##STR2## (wherein R.sub.1 -R.sub.5 and R.sub.6 -R.sub.10 are as hereinbefore defined); at least one of R.sub.1 -R.sub.5 and at least one of R.sub.6 -R.sub.10 being lower alkyl grops.] These compounds are capable of forming and precipitating crystalline complexes with alcohols when added to an aqueous solution of alcohol. Thus, these compounds are useful for separating alcohols from aqueous solutions of alcohols.
    Type: Grant
    Filed: May 8, 1987
    Date of Patent: September 6, 1988
    Inventors: Fumio Toda, Koichi Tanaka
  • Patent number: 4644021
    Abstract: Sustained release antimicrobial agents comprising a clathrate compound composed of a water-soluble antimicrobial agent, and 1,1,6,6-tetraphenyl-2,4-hexadiyne-1,6-diol or 1,1-di(2,4-dimethylphenyl)-2-propyne-1-ol, and methods of fouling control using the same.
    Type: Grant
    Filed: August 16, 1985
    Date of Patent: February 17, 1987
    Assignee: Kurita Water Industries Ltd.
    Inventors: Fumio Toda, Masaru Okamoto, Fujiaki Mochizuki