Abstract: The present disclosure provides, for example, a compound represented by the general formula below or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of the compound or salt: wherein X1, X2, X3 and X4 are each independently —CR2? or N?, R2 is, for example, a halogen atom, R1 is, for example, —S(?O)2—NH—R8, R8 is, for example, a C1-6 alkyl group, R3 is, for example, a hydrogen atom, R5 is, for example, a halogen atom, R6 is, for example, a hydrogen atom, and R4 is, for example, a cyclopropyl group. The compounds, salts or solvates provided by the present disclosure exhibit high RAF/MEK complex-stabilizing activity and can be used for the treatment or prevention of cell proliferative disorders, particularly cancers.

Abstract: Remote manipulation method and system of the master-slave type in which an operation procedure plan is prepared for defining each of a sequence of pieces of work as being performed by manual operation or automatic operation at least on the basis of information on the level of skill of a human operator and the sequence of pieces of work is performed in accordance with the plan, whereby work can be done efficiently with human operator's skill taken into consideration.

Abstract: A method of and apparatus for determining a position of a working original point at which working characteristics of a multi-joint manipulator are at optimum. According to the method and apparatus, a working point at which a hand mounted on the multi-joint manipulator works and a workspace needed for the work are assigned. Subsequently, a set of positions of the working original point of the multi-joint manipulator at which the hand may reach the workspace is calculated. Also, values of evaluation functions representative of preference of the working characteristics of the multi-joint manipulator are calculated with respect to the respective positions of the set. Then, the values of the evaluation functions are compared with each other, thereby selecting the position of the working original point at which the working characteristics are at optimum.

Abstract: An apparatus for automatically charging scrap into an arc furnace wherein an inactive position at which a scrap bucket charged with the scrap is normally placed is provided adjacent to the arc furnace; a transport mechanism is provided so that the scrap bucket is moved between said position and the arc furnace; and the scrap bucket is brought to and stopped at a position right above the arc furnace so as to charge immediately the scrap into the arc furnace within a short time and without overflowing.

Abstract: Disclosed is a television camera having good color reproducibility which is secured to be maintained for a long time even in an atmosphere of high radiation, and in which the degree of deterioration in each color component signal due to radiation exposure is detected and the amplification degree of each color component signal is corrected in accordance with the detected degree of deterioration so as to make the color reproducibility come back to the state before radiation exposure.

Abstract: A trackless scanner for examination of pipings comprises an annular base removably mountable to a plant pipe to be examined, and a plurality of drive wheels for running supported on the base and being in contact with the plant pipe. Each of the drive wheels is associated with a sensor for detecting an angle which the annular base makes when it turns circumferentially of the pipe, a mechanism responsive to a detection signal from the sensor to control the axial running of the drive wheel for running, and a sensor for detecting a curvature of the pipe.

Abstract: A suction duct having two opposed suction ports is disposed at the top wall of a shroud for a steel making arc furnace such that the two suction ports are in opposed relationship with respect to each other across an opening formed through the top wall of the shroud for permitting the lateral movement of a scrap bucket suspension device. An injection pipe or pipes are horizontally disposed in the suction port such that the injection pipes disposed in one of the suction ports are staggered vertically with respect to those disposed in the other suction port. A fluid is horizontally sprayed from a nozzle or nozzles of the injection pipes across the opening so that vertically spaced fluid shelves are formed across the opening.

Abstract: A multiarticulated manipulator including a multijoint connecting mechanism having a plurality of arms, each arm having a joint capable of being bent in one plane and all the arms being connected with one another in positions spaced apart from one another by circumferential extent of 90 degrees. A plurality of wires are provided, each wire being connected to one of the arms and all the wires being supported and guided by wire guides and driven by a drive. The multiarticulated manipulator incorporated in a movable type remoted-controlled visual monitor system further includes a lens fixed to a forward end of the multijoint connecting mechanism, a fiberscope connected to the lens, and a movable member having the drive mounted therein and supporting the multijoint connecting mechanism, and a camera mounted in the movable member and connected to the lens through the fiberscope.

Abstract: In the present invention, many cooling pipes are arranged horizontally at least in any one of the walls or roof of a furnace, to be fitted at the respective ends on both sides with supporting pipes provided outside the furnace, to let the cooling medium flow in one system for high cooling efficiency and long life. The cooling pipes may be arranged in ladder fashion or in a similar way, to keep the splash film stable, thereby preventing the decrease of the thermal efficiency of the furnace.

Abstract: This invention relates to a shroud for a steel making electric-arc furnace which surrounds the electric-arc furnace main body for sound- and dust-proofing, having doors provided in the side wall of the shroud to permit the scrap bucket to move in and out of the shroud and an opening of a minimum width in the suction port of a dust collecting suction duct on the top wall to permit transverse movement of the bucket lifting means to the center of the electric-arc furnace main body.

Abstract: In a reactor, fine iron ore solids are made to descend through the fluidized bed of fine carbon bearing particles sustained within the reactor so that the fine iron ore solids may be reduced and simultaneously the reducing gas may be produced. The direct reduction efficiency may be considerably improved.