Patents by Inventor Fuqiang Chen

Fuqiang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UNIVERSAL LIGATION ARRAY FOR ANALYZING GENE EXPRESSION OR GENOMIC VARIATIONS
    Publication number: 20090061424
    Abstract: The present invention provides an array system comprising a plurality of immobilized oligonucleotides comprising artificial sequences and a plurality of complementary ligation templates, as well as methods and kits for using the array system to analyze populations of nucleic acids. In particular, target nucleic acids are ligated to the immobilized oligonucleotides on the array in the presence of the complementary ligation templates.
    Type: Application
    Filed: August 30, 2007
    Publication date: March 5, 2009
    Applicant: SIGMA-ALDRICH COMPANY
    Inventor: Fuqiang CHEN
  • DETECTION OF MATURE SMALL RNA MOLECULES
    Publication number: 20080194416
    Abstract: Methods, compositions, and kits for detecting mature small RNAs are provided herein. The methods comprise ligating at least one linker to a mature small RNA in the presence of a complementary ligation template to generate a ligation product. The ligation product is a hybrid molecule comprising the linker and the mature small RNA.
    Type: Application
    Filed: February 8, 2007
    Publication date: August 14, 2008
    Applicant: SIGMA ALDRICH
    Inventor: Fuqiang Chen
  • Compositions and Methods for Isolation of Biological Molecules
    Publication number: 20080023395
    Abstract: The present invention provides charged separation media, kits comprising the separation media, and methods of using the same to bind and optionally isolate biological molecules. The charged separation media and methods utilize a polyion non-covalently bound to the separation media to bind the desired biological molecule to the separation media.
    Type: Application
    Filed: July 31, 2006
    Publication date: January 31, 2008
    Applicant: SIGMA ALDRICH CO.
    Inventors: Fuqiang Chen, Carol Kreader
  • Compositions and Methods for Isolation of Biological Molecules
    Publication number: 20080026375
    Abstract: The present invention provides charged separation media, kits comprising the separation media, and methods of using the same to bind and optionally isolate biological molecules. The charged separation media and methods utilize a polyion non-covalently bound to the separation media to bind the desired biological molecule to the separation media.
    Type: Application
    Filed: July 31, 2006
    Publication date: January 31, 2008
    Applicant: SIGMA ALDRICH CO.
    Inventors: Fuqiang Chen, Carol Kreader
  • Compositions and Methods for Isolation of Biological Molecules
    Publication number: 20080026374
    Abstract: The present invention provides charged separation media, kits comprising the separation media, and methods of using the same to bind and optionally isolate biological molecules. The charged separation media and methods utilize a polyion non-covalently bound to the separation media to bind the desired biological molecule to the separation media.
    Type: Application
    Filed: July 31, 2006
    Publication date: January 31, 2008
    Applicant: SIGMA ALDRICH CO.
    Inventors: Fuqiang Chen, Carol Kreader
  • Methods and compositions for the rapid isolation of small RNA molecules
    Publication number: 20070202511
    Abstract: The present invention provides extraction compositions and methods for the rapid and efficient isolation of small RNA molecules from a biological sample. In particular, the extraction compositions, when contacted with a biological sample, releases the small RNA molecules from the other molecules in a biological sample, and the released small RNA molecules may then be isolated.
    Type: Application
    Filed: February 28, 2006
    Publication date: August 30, 2007
    Inventors: Fuqiang Chen, Carol Kreader
  • Method for the Isolation of RNA from Biological Sources
    Publication number: 20070087369
    Abstract: Methods and kits for isolating RNA are provided that enable rapid RNA preparation from biological sources. In one aspect, RNA is isolated from difficult plant tissues and cells that contain high levels of secondary metabolites, without employing organic extraction or salt precipitation procedures. This method employs novel lysing and binding conditions to allow preparation of RNA free from secondary metabolites.
    Type: Application
    Filed: November 29, 2006
    Publication date: April 19, 2007
    Applicant: SIGMA ALDRICH CO.
    Inventors: Fuqiang Chen, David Cutter
  • Method for the isolation of RNA from biological sources
    Publication number: 20070015165
    Abstract: Methods and kits for isolating RNA are provided that enable rapid RNA preparation from biological sources. In one aspect, RNA is isolated from difficult plant tissues and cells that contain high levels of secondary metabolites, without employing organic extraction or salt precipitation procedures. This method employs novel lysing and binding conditions to allow preparation of RNA free from secondary metabolites.
    Type: Application
    Filed: July 13, 2005
    Publication date: January 18, 2007
    Applicant: Sigma-Aldrich Co.
    Inventors: Fuqiang Chen, David Cutter
  • Process for the reduction of endotoxins in a plasmid preparation using a carbohydrate non-ionic detergent with silica chromatography
    Publication number: 20050245733
    Abstract: The present invention provides methods for the reduction of endotoxins in a plasmid preparation using a carbohydrate non-ionic detergent with silica chromatography.
    Type: Application
    Filed: April 18, 2005
    Publication date: November 3, 2005
    Inventors: Kevin Ray, Carol Kreader, Fuqiang Chen, David Cutter
  • Rapid preparation of nucleic acids by enzymatic digestion
    Publication number: 20050164260
    Abstract: The present invention provides methods, compositions and kits for isolating and purifying at least one nucleic acid directly from a biological sample, or for preparing a biological sample for subsequent isolation and purification of at least one nucleic acid, without removal of the biological sample's cell culture medium or cellular fluid.
    Type: Application
    Filed: December 30, 2004
    Publication date: July 28, 2005
    Applicant: Sigma-Aldrich Co.
    Inventor: Fuqiang Chen