Patents by Inventor Géraldine Agusti

Géraldine Agusti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of embolization using a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of polyl(vinyl alcohol)
    Patent number: 9434800
    Abstract: A method of embolizing an area of treatment includes providing a composition that includes a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of poly(vinyl alcohol) consisting of a poly(vinyl alcohol) (PVA) having covalently grafted thereon iodinated benzyl groups comprising from 1 to 4 iodine atoms per benzyl group as the only substituents wherein a grafted repeating unit has formula (I) wherein n is from 1 to 4: and introducing the composition into the area of treatment.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: September 6, 2016
    Assignees: ANTIA THERAPEUTICS S.A., UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Yves Chevalier, Géraldine Agusti, Coralie Nyffenegger, Eric Doelker, Olivier Jordan, Gert Andersen
  • Method of Embolization using a Radiopaque, Non-Biodegradable, Water-Insoluble Iodinated Benzyl Ether of PolyI(Vinyl Alcohol)
    Publication number: 20150335779
    Abstract: A method of embolizing an area of treatment includes providing a composition that includes a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of poly(vinyl alcohol) consisting of a poly(vinyl alcohol) (PVA) having covalently grafted thereon iodinated benzyl groups comprising from 1 to 4 iodine atoms per benzyl group as the only substituents wherein a grafted repeating unit has formula (I) wherein n is from 1 to 4: and introducing the composition into the area of treatment.
    Type: Application
    Filed: July 8, 2015
    Publication date: November 26, 2015
    Applicants: ANTIA THERAPEUTICS S.A., UNIVERSITÈ CLAUDE BERNARD LYON 1 (UCBL), Centre National de la Recherche Scientifique (CNRS)
    Inventors: Yves Chevalier, Géraldine Agusti, Coralie Nyffenegger, Eric Doelker, Olivier Jordan, Gert Andersen
  • Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof
    Patent number: 9115230
    Abstract: The invention concerns a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of poly(vinyl alcohol) consisting of a PVA having covalently grafted thereon iodinated benzyl groups comprising 1-4 iodine atoms per benzyl group, a process for preparing the same comprising reacting a 0-100% hydrolyzed PVA with a iodinated benzyl derivative comprising 1-4 iodine atoms per benzyl group in a polar aprotic solvent in the presence of a base in anhydrous conditions. Said iodo-benzylether-PVA is particularly useful as embolic agent in an injectable embolizing composition. The invention also concerns an injectable embolizing composition comprising said iodo-benzylether-PVA and capable of forming a cohesive mass upon contact with a body fluid by precipitation of the iodo-benzylether-PVA. Said injectable embolizing composition is particularly useful for forming in-situ a cohesive mass in a blood vessel or into a tumor.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: August 25, 2015
    Assignees: ANTIA THERAPEUTICS S.A., UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Yves Chevalier, Géraldine Agusti, Coralie Nyffenegger, Eric Doelker, Olivier Jordan, Gert Andersen
  • RADIOPAQUE, NON-BIODEGRADABLE, WATER-INSOLUBLE IODINATED BENZYL ETHERS OF POLY(VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF
    Publication number: 20130108574
    Abstract: The invention concerns a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of poly(vinyl alcohol) consisting of a PVA having covalently grafted thereon iodinated benzyl groups comprising 1-4 iodine atoms per benzyl group, a process for preparing the same comprising reacting a 0-100% hydrolyzed PVA with a iodinated benzyl derivative comprising 1-4 iodine atoms per benzyl group in a polar aprotic solvent in the presence of a base in anhydrous conditions. Said iodo-benzylether-PVA is particularly useful as embolic agent in an injectable embolizing composition. The invention also concerns an injectable embolizing composition comprising said iodo-benzylether-PVA and capable of forming a cohesive mass upon contact with a body fluid by precipitation of the iodo-benzylether-PVA. Said injectable embolizing composition is particularly useful for forming in-situ a cohesive mass in a blood vessel or into a tumor.
    Type: Application
    Filed: March 9, 2011
    Publication date: May 2, 2013
    Inventors: Yves Chevalier, Géraldine Agusti, Coralie Nyffenegger, Eric Doelker, Olivier Jordan, Gert Andersen