Patents by Inventor Gérard Adam

Gérard Adam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-aminochroman spiro compounds
    Patent number: 5376661
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, A and m are as defined in the description.Medicinal product which is useful for treating depression and anxiety.
    Type: Grant
    Filed: March 24, 1993
    Date of Patent: December 27, 1994
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Tchao Podona, Gerard Adam, Beatrice Guardiola, Pierre Renard
  • Thiochroman compounds
    Patent number: 5371103
    Abstract: The invention relates to compounds of the formula I: ##STR1## in which R.sub.1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, andmedicinal products which are useful for treating Central Nervous System disorders.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: December 6, 1994
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Gerard Coudert, Tchao Podona, Beatrice Guardiola-Lemaitre, Pierre Renard, Gerard Adam, Daniel Henri-Caignard
  • New 1-(alkoxybenzyl)piperazine amide compounds
    Patent number: 5340809
    Abstract: A compound selected from those of formula (I): ##STR1## with R.sub.1, R.sub.2 and n as defined in the description, and medicinal products containing the same useful in treating or in preventing a disorder resulting from cellular damages following upon ischemia, hypoxia, or anoxia.
    Type: Grant
    Filed: August 13, 1992
    Date of Patent: August 23, 1994
    Assignee: ADIR et Compagnie
    Inventors: Michel Gaudry, Bruno Pfeiffer, Pierre Renard, Jean-Francois Renaud de la Faverie, Gerard Adam
  • Thiochroman compounds
    Patent number: 5332741
    Abstract: The invention relates to compounds of the formula I: ##STR1## in which R.sub.1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, andmedicinal products which are useful for treating Central Nervous System disorders.
    Type: Grant
    Filed: May 17, 1993
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Gerard Coudert, Tchao Podona, Beatrice Guardiola-Lemaitre, Pierre Renard, Gerard Adam, Daniel Henri-Caignard
  • Compounds of N-benzoylpyroline
    Patent number: 5332735
    Abstract: Compounds of the general formula (I): ##STR1## where A, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are defined in the description.Medicinal products.
    Type: Grant
    Filed: November 14, 1991
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Marie P. Foloppe, Max Robba, Michel Boulouard, Pierre Renard, Michelle Devissaguet, Gerard Adam
  • Naphthalene amides and sulphonamides, processes for their preparation and pharmaceutical compositions containing them
    Patent number: 5332759
    Abstract: The invention relates to compounds of the general formula (I): ##STR1## wherein R.sub.3 represents a group ##STR2## R.sub.1, R.sub.2, R.sub.6, R.sub.7 being as defined in the description. Medicinal product useful in treating a disorder due to vasodilatation of the vascular system.
    Type: Grant
    Filed: January 21, 1993
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Patrick Depreux, Daniel Lesieur, Habib Abdellaoui, Beatrice Guardiola, Gerard Adam, Pierre Renard, Bruno Pfeiffer
  • Benzoxazolinonyl alkylamides
    Patent number: 5326775
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: July 5, 1994
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzoxazalinonyl and benzothiazolinonyl ethyl isonicotine amides and piperidonamides
    Patent number: 5322849
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: June 21, 1994
    Assignee: Adir Et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzoxazolinonyl and benzothiazolinonyl ethyl morpholinoacetamides
    Patent number: 5322843
    Abstract: Compounds of general formula (I): ##STR1## wherein R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: June 21, 1994
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Process for the synthesis of enantiomers of 3-aminochroman compounds
    Patent number: 5322944
    Abstract: Process for preparing enantiomers of general formula (I): ##STR1## where Z, R.sub.1, R.sub.2, R.sub.3 and n are defined in the description. The compounds obtained according to the invention are useful as medicinal products.
    Type: Grant
    Filed: June 30, 1992
    Date of Patent: June 21, 1994
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Claude Fugier, Jean-Claude J. Souvie, Gerard Adam, Pierre Renard, Daniel-Henri Caignard
  • Benzopyran compounds
    Patent number: 5315017
    Abstract: A compound selected from the group consisting of those of formula I ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, X and n are defined in the description, an optical isomer thereof, and an addition salt thereof with a pharmaceutically-acceptable base or acid.Medicinal product which is useful in treating or in preventing a disorder due to or linked to the phenomena of peroxidation and to the disturbance of the eicosanoid biosynthesis.
    Type: Grant
    Filed: May 1, 1992
    Date of Patent: May 24, 1994
    Assignee: Adir Et Compagnie
    Inventors: Guillaume Le Baut, Jean-Paul Babingui, Jacqueline Courant, Jean-Michel Robert, Pierre Renard, Daniel-Henri Caignard, Jean-Francois R. de la Faverie, Gerard Adam
  • 1-amidooctahydropyrido[2,1-c][1,4]oxazine compounds
    Patent number: 5310739
    Abstract: The invention relates to the compounds of general formula ##STR1## in which R.sub.1, R.sub.2, R.sub.4, R.sub.5 and A are as defined in the description.their isomers, diastereoisomers, and enantiomers as well as their addition salts with a pharmaceutically acceptable inorganic or organic acid, andmedicinal products containing the same which are usable for the treatment of psycho-behavioral disorders.
    Type: Grant
    Filed: May 13, 1992
    Date of Patent: May 10, 1994
    Assignee: Adir et Compagnie
    Inventors: Henri P. Husson, Jean C. Quirion, Martine Bonin, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzofuran ethylamine compounds
    Patent number: 5308866
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which Ar', R.sub.1 and R.sub.2 are as defined in the specification, an optical isomer,and an addition salt thereof with a pharmaceutically-acceptable acid or base.Medicinal product which is useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: July 19, 1993
    Date of Patent: May 3, 1994
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Jean Andrieux, Gerard Adam, Daniel H. Caignard, Beatrice Guardiola
  • New heterocycle-substituted alkylamides
    Patent number: 5300507
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleeping disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: April 5, 1994
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Aminoalkyl benzoxazine and benzthiazine compounds having a high 5-HT.sub.1A affinity
    Patent number: 5296477
    Abstract: Compounds of general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, n, X and A are defined in the description.Medicinal products containing the same are useful as antidepressives or anxiolytics due to their 5-HT1A receptor agonist activity.
    Type: Grant
    Filed: December 1, 1992
    Date of Patent: March 22, 1994
    Assignee: Adir et Compagnie
    Inventors: Thierry Taverne, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzopyran compounds
    Patent number: 5290797
    Abstract: A compound selected from those of the formula I: ##STR1## in which: R.sub.1 represents hydrogen or alkyl having 1 to 3 inclusive carbon atoms,R represents hydrogen, alkyl having 1 to 4 inclusive carbon atoms, or acyl --CO--R' in which R' represents alkyl having 1 to 4 inclusive carbon atoms,X represents O or H.sub.2,an isomer,and an addition salt thereof with a pharmaceutically-acceptable acid or base, andmedicinal products containing the same which are useful in treating or in preventing disorder resulting from or associated with phenomena of peroxidation and disturbance of the synthesis of eicosanoids.
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: March 1, 1994
    Assignee: Adir et Compagnie
    Inventors: Guillaume Le Baut, Jean-Paul Babingui, Jean-Michel Robert, Pierre Renard, Jean-Francois Renaud de la Faverie, Gerard Adam
  • Arylethylamine compounds
    Patent number: 5276051
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which Ar', R.sub.1 and R.sub.2 are as defined in the specification, an optical isomer,and an addition salt thereof with a pharmaceutically-acceptable acid or base.Medicinal product which is useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: August 12, 1992
    Date of Patent: January 4, 1994
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Jean Andrieux, Gerard Adam, Daniel H. Caignard, Beatrice Guardiola
  • Aminoalkyl-benzothiazolinone and -benzoxazolinone compounds having a high 5-HT1A affinity
    Patent number: 5268381
    Abstract: Compounds of general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, n, X and A are defined in the description. Medicinal products containing the same are useful as antidepressives or anxiolytics due to their 5-HT1A receptor agonist activity.
    Type: Grant
    Filed: September 16, 1992
    Date of Patent: December 7, 1993
    Assignee: Adir et Compagnie
    Inventors: Thierry Taverne, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Compounds having an aryltriazine structure
    Patent number: 5254548
    Abstract: A compound having an aryltriazine structure selected from those of formula (I): ##STR1## for which the meaning of the substituents Ar, R.sub.1, R.sub.5, R.sub.6, and R.sub.6 ' is given in the description.The compound of the invention is useful as medicinal product for disorders associated with a cholinergic dysfunction.
    Type: Grant
    Filed: January 14, 1992
    Date of Patent: October 19, 1993
    Assignee: Adir et Compagnie
    Inventors: Camille-Georges Wermuth, Jean-Jacques Bourguignon, Isabelle Morin, Pierre Renard, Michelle Devissaguet, Jean-Francois R. de La Faverie, Gerard Adam
  • New benzoselenazolinone compounds
    Patent number: 5246951
    Abstract: Compounds of general formula (I): ##STR1## where R.sub.1, R.sub.2, R.sub.4, A and B are defined in the description. Medicinal products.
    Type: Grant
    Filed: November 22, 1991
    Date of Patent: September 21, 1993
    Assignee: Adir et Compagnie
    Inventors: Vincent Galet, Marie-Pierre Vaccher, Daniel Lesieur, Pierre Renard, Daniel H. Caignard, Jean-Francois Renaud de la Faverie, Gerard Adam